| Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors PYS Lam, PK Jadhav, CJ Eyermann, CN Hodge, Y Ru, LT Bacheler, ... Science 263 (5145), 380-384, 1994 | 1146 | 1994 |
| Core-electron binding energies for gaseous atoms and molecules WL Jolly, KD Bomben, CJ Eyermann Atomic Data and Nuclear Data Tables 31 (3), 433-493, 1984 | 434 | 1984 |
| Identification of 4-substituted 1, 2, 3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A F Reck, F Zhou, M Girardot, G Kern, CJ Eyermann, NJ Hales, RR Ramsay, ... Journal of medicinal chemistry 48 (2), 499-506, 2005 | 345 | 2005 |
| Cyclic HIV protease inhibitors: synthesis, conformational analysis, P2/P2 ‘structure− activity relationship, and molecular recognition of cyclic ureas PYS Lam, Y Ru, PK Jadhav, PE Aldrich, GV DeLucca, CJ Eyermann, ... Journal of medicinal chemistry 39 (18), 3514-3525, 1996 | 258 | 1996 |
| Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450 CN Hodge, PE Aldrich, LT Bacheler, CH Chang, CJ Eyermann, S Garber, ... Chemistry & biology 3 (4), 301-314, 1996 | 178 | 1996 |
| SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids J Jansen, KC Reimer, JS Nagai, FS Varghese, GJ Overheul, M de Beer, ... Cell Stem Cell 29 (2), 217-231. e8, 2022 | 173 | 2022 |
| NMR and X-ray evidence that the HIV protease catalytic aspartyl groups are protonated in the complex formed by the protease and a non-peptide cyclic urea-based inhibitor T Yamazaki, LK Nicholson, P Wingfield, SJ Stahl, JD Kaufman, ... Journal of the American Chemical Society 116 (23), 10791-10792, 1994 | 166 | 1994 |
| Structural studies of a family of high affinity ligands for GPIIb/IIIa AC Bach, CJ Eyermann, JD Gross, MJ Bower, RL Harlow, PC Weber, ... Journal of the American Chemical Society 116 (8), 3207-3219, 1994 | 144 | 1994 |
| Discovery of potent and selective SH2 inhibitors of the tyrosine kinase ZAP-70 CB Vu, EG Corpuz, TJ Merry, SG Pradeepan, C Bartlett, RS Bohacek, ... Journal of medicinal chemistry 42 (20), 4088-4098, 1999 | 128 | 1999 |
| Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: broad-spectrum antibacterial agents with reduced hERG activity F Reck, R Alm, P Brassil, J Newman, B DeJonge, CJ Eyermann, G Breault, ... Journal of medicinal chemistry 54 (22), 7834-7847, 2011 | 116 | 2011 |
| Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors PYS Lam, PK Jadhav, CJ Eyermann, CN Hodge, GV De Lucca, ... US Patent 5,811,422, 1998 | 79 | 1998 |
| NMR evidence for the displacement of a conserved interior water molecule in HIV protease by a non-peptide cyclic urea-based inhibitor S Grzesiek, A Bax, LK Nicholson, T Yamazaki, P Wingfield, SJ Stahl, ... Journal of the American Chemical Society 116 (4), 1581-1582, 1994 | 78 | 1994 |
| Molecular recognition of cyclic urea HIV-1 protease inhibitors PJ Ala, RJ DeLoskey, EE Huston, PK Jadhav, PYS Lam, CJ Eyermann, ... Journal of Biological Chemistry 273 (20), 12325-12331, 1998 | 76 | 1998 |
| SRC homology-2 inhibitors: peptidomimetic and nonpeptide TK Sawyer, RS Bohacek, DC Dalgarno, CJ Eyermann, N Kawahata, ... Mini reviews in medicinal chemistry 2 (5), 475-488, 2002 | 73 | 2002 |
| Nonpeptide cyclic cyanoguanidines as HIV-1 protease inhibitors: synthesis, structure− activity relationships, and X-ray crystal structure studies PK Jadhav, FJ Woerner, PYS Lam, CN Hodge, CJ Eyermann, HW Man, ... Journal of medicinal chemistry 41 (9), 1446-1455, 1998 | 66 | 1998 |
| Transformations of resin-bound pyridinium ylides: I. A stereoselective synthesis of 2, 2, 3-trisubstituted cyclopropanecarboxylates NH Vo, CJ Eyermann, CN Hodge Tetrahedron letters 38 (46), 7951-7954, 1997 | 64 | 1997 |
| Calculated and experimental low-energy conformations of cyclic urea HIV protease inhibitors CN Hodge, PYS Lam, CJ Eyermann, PK Jadhav, Y Ru, CH Fernandez, ... Journal of the American Chemical Society 120 (19), 4570-4581, 1998 | 56 | 1998 |
| Plasmodial kinase inhibitors: license to cure? DG Cabrera, A Horatscheck, CR Wilson, G Basarab, CJ Eyermann, ... Journal of Medicinal Chemistry 61 (18), 8061-8077, 2018 | 54 | 2018 |
| Novel substituted (pyridin-3-yl) phenyloxazolidinones: antibacterial agents with reduced activity against monoamine oxidase A and increased solubility F Reck, F Zhou, CJ Eyermann, G Kern, D Carcanague, G Ioannidis, ... Journal of medicinal chemistry 50 (20), 4868-4881, 2007 | 53 | 2007 |
| Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines B Geng, G Basarab, J Comita-Prevoir, M Gowravaram, P Hill, A Kiely, ... Bioorganic & medicinal chemistry letters 19 (3), 930-936, 2009 | 52 | 2009 |
