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Amit Roy
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Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3, 3′-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular …
Amit Roy, Agneyo Ganguly, Somdeb BoseDasgupta, Benu Brata Das, Churala Pal ...
Molecular Pharmacology 74 (5), 1292-1307, 2008
1902008
Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani
Rakhee Das, Amit Roy, Neeta Dutta, Hemanta K.Majumder
Apoptosis 13 (7), 867-882, 2008
1762008
Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species–mediated apoptotic topoisomerase I–DNA cleavable complex formation in prostate cancer …
Agneyo Ganguly, Benu Brata Das, Amit Roy, Nilkantha Sen, Somdeb BoseDasgupta ...
Cancer Research 67 (24), 11848-11858, 2007
1132007
Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement
Sissel Juul, Christine Nielsen, Rodrigo Labouriau, Amit Roy, Cinzia Tesauro ...
ACS nano 6 (12), 10676-10683, 2012
982012
Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin …
Benu Brata Das, Nilkantha Sen, Amit Roy, Somdeb BoseDasgupta, Agneyo Ganguly ...
Nucleic Acids Research 34 (4), 1121-1132, 2006
872006
The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA ‘degradesome’
Somdeb BoseDasgupta, Benu Brata Das, Souvik Sengupta, Agneyo Ganguly, Amit ...
Cell Death & Differentiation 15 (10), 1629-1640, 2008
822008
A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania
Somdeb BoseDasgupta, Agneyo Ganguly, Amit Roy, Tanmoy Mukherjee, Hemanta K ...
Molecular and Biochemical Parasitology 158 (2), 176-188, 2008
472008
Withanolide Z, a new chlorinated withanolide from Withania somnifera
Swapan Pramanick, Amit Roy, Shekher Ghosh, Hemanta K.Majumder, Sibabrata ...
Planta Medica 74 (14), 1745, 2008
422008
An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3, 3′-di-indolylmethane, a novel DNA topoisomerase I poison with …
Amit Roy, Benu Brata Das, Agneyo Ganguly, Somdeb Bose Dasgupta, Neeta ...
Biochemical Journal 409 (2), 611-622, 2008
422008
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations
Niels Frank Jensen1, Keli Agama, Amit Roy, David Hersi Smith, Thomas D ...
Journal of Experimental & Clinical Cancer Research 35 (56), 2016
392016
Decreased Camptothecin Sensitivity of the Stem-Cell-like Fraction of Caco2 cells Correlates with an Altered Phosphorylation Pattern of Topoisomerase I
Amit Roy, Cinzia Tesauro, Rikke Frøhlich, Marianne S. Hede, Maria J. Nielsen ...
PLoS ONE 9 (6), e99628, 2014
252014
Copper salisylaldoxime (CuSAL) imparts protective efficacy against visceral leishmaniasis by targeting Leishmania donovani topoisomerase IB
Manoj Kumar Singh,......, Hemanta K. Majumder, Amit Roy*
Experimental Parasitology 175, 8-20, 2017
242017
A tyrosyl DNA phosphodiesterase 1 from kinetoplastid parasite Leishmania donovani (LdTdp1) capable of removing topo I–DNA covalent complexes
Bijoylaxmi Banerjee, Amit Roy, Nilkantha Sen, Hemanta K.Majumder
Molecular Microbiology 78 (1), 119-137, 2010
242010
Development of derivatives of 3, 3′-diindolylmethane as potent Leishmania donovani Bi-subunit topoisomerase IB poisons
Amit Roy, Sayan Chowdhury, Souvik Sengupta, Madhumita Mandal, Parasuraman ...
PloS One 6 (12), e28493, 2011
232011
Topoisomerase I as a biomarker: Detection of activity at the single molecule level
Joanna Proszek, Amit Roy, Ann-Katrine Jakobsen, Magnus Stougaard
Sensors 14, 1195-1207, 2014
222014
‘LeishMan’topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani
Agneyo Ganguly, Benu Brata Das, Nilkantha Sen, Amit Roy, Somdeb BoseDasgupta ...
Nucleic Acids Research 34 (21), 6286-6297, 2006
192006
Peptide inhibition of topoisomerase IB from Plasmodium falciparum
Amit Roy, Ilda D'Annessa, Christine Nielsen, David Tordrup, Rune R Laursen ...
Molecular Biology International 2011, 2011
172011
The large subunit of Leishmania topoisomerase I functions as the ‘molecular steer’in type IB topoisomerase
Somdeb BoseDasgupta, Agneyo Ganguly, Benu Brata Das, Amit Roy, Neeta Khalkho ...
Molecular Microbiology 67 (1), 31-46, 2008
152008
Leishmania donovani bisubunit topoisomerase I gene fusion leads to an active enzyme with conserved type IB enzyme function
Benu Brata Das, Somdeb BoseDasgupta, Agneyo Ganguly, Saumyabrata Mazumder ...
The FEBS Journal 274 (1), 150-163, 2007
152007
Road-map of pre-clinical treatment for Visceral Leishmaniasis
Priyanka Mazire, Vartika Agarwal and Amit Roy*
Drug Development Research 83 (2), 317-327, 2022
13*2022
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