Mitochondria-dependent reactive oxygen species-mediated programmed cell death induced by 3, 3′-diindolylmethane through inhibition of F0F1-ATP synthase in unicellular … Amit Roy, Agneyo Ganguly, Somdeb BoseDasgupta, Benu Brata Das, Churala Pal ... Molecular Pharmacology 74 (5), 1292-1307, 2008 | 190 | 2008 |
Reactive oxygen species and imbalance of calcium homeostasis contributes to curcumin induced programmed cell death in Leishmania donovani Rakhee Das, Amit Roy, Neeta Dutta, Hemanta K.Majumder Apoptosis 13 (7), 867-882, 2008 | 176 | 2008 |
Betulinic acid, a catalytic inhibitor of topoisomerase I, inhibits reactive oxygen species–mediated apoptotic topoisomerase I–DNA cleavable complex formation in prostate cancer … Agneyo Ganguly, Benu Brata Das, Amit Roy, Nilkantha Sen, Somdeb BoseDasgupta ... Cancer Research 67 (24), 11848-11858, 2007 | 113 | 2007 |
Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement Sissel Juul, Christine Nielsen, Rodrigo Labouriau, Amit Roy, Cinzia Tesauro ... ACS nano 6 (12), 10676-10683, 2012 | 98 | 2012 |
Differential induction of Leishmania donovani bi-subunit topoisomerase I–DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin … Benu Brata Das, Nilkantha Sen, Amit Roy, Somdeb BoseDasgupta, Agneyo Ganguly ... Nucleic Acids Research 34 (4), 1121-1132, 2006 | 87 | 2006 |
The caspase-independent algorithm of programmed cell death in Leishmania induced by baicalein: the role of LdEndoG, LdFEN-1 and LdTatD as a DNA ‘degradesome’ Somdeb BoseDasgupta, Benu Brata Das, Souvik Sengupta, Agneyo Ganguly, Amit ... Cell Death & Differentiation 15 (10), 1629-1640, 2008 | 82 | 2008 |
A novel ATP-binding cassette transporter, ABCG6 is involved in chemoresistance of Leishmania Somdeb BoseDasgupta, Agneyo Ganguly, Amit Roy, Tanmoy Mukherjee, Hemanta K ... Molecular and Biochemical Parasitology 158 (2), 176-188, 2008 | 47 | 2008 |
Withanolide Z, a new chlorinated withanolide from Withania somnifera Swapan Pramanick, Amit Roy, Shekher Ghosh, Hemanta K.Majumder, Sibabrata ... Planta Medica 74 (14), 1745, 2008 | 42 | 2008 |
An insight into the mechanism of inhibition of unusual bi-subunit topoisomerase I from Leishmania donovani by 3, 3′-di-indolylmethane, a novel DNA topoisomerase I poison with … Amit Roy, Benu Brata Das, Agneyo Ganguly, Somdeb Bose Dasgupta, Neeta ... Biochemical Journal 409 (2), 611-622, 2008 | 42 | 2008 |
Characterization of DNA topoisomerase I in three SN-38 resistant human colon cancer cell lines reveals a new pair of resistance-associated mutations Niels Frank Jensen1, Keli Agama, Amit Roy, David Hersi Smith, Thomas D ... Journal of Experimental & Clinical Cancer Research 35 (56), 2016 | 39 | 2016 |
Decreased Camptothecin Sensitivity of the Stem-Cell-like Fraction of Caco2 cells Correlates with an Altered Phosphorylation Pattern of Topoisomerase I Amit Roy, Cinzia Tesauro, Rikke Frøhlich, Marianne S. Hede, Maria J. Nielsen ... PLoS ONE 9 (6), e99628, 2014 | 25 | 2014 |
Copper salisylaldoxime (CuSAL) imparts protective efficacy against visceral leishmaniasis by targeting Leishmania donovani topoisomerase IB Manoj Kumar Singh,......, Hemanta K. Majumder, Amit Roy* Experimental Parasitology 175, 8-20, 2017 | 24 | 2017 |
A tyrosyl DNA phosphodiesterase 1 from kinetoplastid parasite Leishmania donovani (LdTdp1) capable of removing topo I–DNA covalent complexes Bijoylaxmi Banerjee, Amit Roy, Nilkantha Sen, Hemanta K.Majumder Molecular Microbiology 78 (1), 119-137, 2010 | 24 | 2010 |
Development of derivatives of 3, 3′-diindolylmethane as potent Leishmania donovani Bi-subunit topoisomerase IB poisons Amit Roy, Sayan Chowdhury, Souvik Sengupta, Madhumita Mandal, Parasuraman ... PloS One 6 (12), e28493, 2011 | 23 | 2011 |
Topoisomerase I as a biomarker: Detection of activity at the single molecule level Joanna Proszek, Amit Roy, Ann-Katrine Jakobsen, Magnus Stougaard Sensors 14, 1195-1207, 2014 | 22 | 2014 |
‘LeishMan’topoisomerase I: an ideal chimera for unraveling the role of the small subunit of unusual bi-subunit topoisomerase I from Leishmania donovani Agneyo Ganguly, Benu Brata Das, Nilkantha Sen, Amit Roy, Somdeb BoseDasgupta ... Nucleic Acids Research 34 (21), 6286-6297, 2006 | 19 | 2006 |
Peptide inhibition of topoisomerase IB from Plasmodium falciparum Amit Roy, Ilda D'Annessa, Christine Nielsen, David Tordrup, Rune R Laursen ... Molecular Biology International 2011, 2011 | 17 | 2011 |
The large subunit of Leishmania topoisomerase I functions as the ‘molecular steer’in type IB topoisomerase Somdeb BoseDasgupta, Agneyo Ganguly, Benu Brata Das, Amit Roy, Neeta Khalkho ... Molecular Microbiology 67 (1), 31-46, 2008 | 15 | 2008 |
Leishmania donovani bisubunit topoisomerase I gene fusion leads to an active enzyme with conserved type IB enzyme function Benu Brata Das, Somdeb BoseDasgupta, Agneyo Ganguly, Saumyabrata Mazumder ... The FEBS Journal 274 (1), 150-163, 2007 | 15 | 2007 |
Road-map of pre-clinical treatment for Visceral Leishmaniasis Priyanka Mazire, Vartika Agarwal and Amit Roy* Drug Development Research 83 (2), 317-327, 2022 | 13* | 2022 |