Tihomir Tomasic
Tihomir Tomasic
Associate Professor of Medicinal Chemistry
Verified email at ffa.uni-lj.si - Homepage
Title
Cited by
Cited by
Year
Rhodanine as a privileged scaffold in drug discovery
T Tomasic, LP Masic
Current Medicinal Chemistry 16 (13), 1596-1629, 2009
2872009
Rhodanine as a scaffold in drug discovery: a critical review of its biological activities and mechanisms of target modulation
T Tomašić, L Peterlin Mašič
Expert opinion on drug discovery 7 (7), 549-560, 2012
1542012
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2, 4-dione inhibitors of MurD ligase
N Zidar, T Tomašić, R Sink, V Rupnik, A Kovac, S Turk, D Patin, D Blanot, ...
Journal of medicinal chemistry 53 (18), 6584-6594, 2010
1062010
Discovery of 4,5,6,7-Tetrahydrobenzo[1,2-d]thiazoles as Novel DNA Gyrase Inhibitors Targeting the ATP-Binding Site
T Tomasic, S Katsamakas, Z Hodnik, J Ilaš, M Brvar, T Solmajer, ...
Journal of medicinal chemistry 58 (14), 5501-5521, 2015
1022015
Prospects for developing new antibacterials targeting bacterial type IIA topoisomerases
T Tomašić, L Peterlin Masic
Current Topics in Medicinal Chemistry 14 (1), 130-151, 2014
1002014
Discovery of benzothiazole scaffold-based DNA gyrase B inhibitors
M Gjorgjieva, T Tomašič, M Barančokova, S Katsamakas, J Ilaš, ...
Journal of medicinal chemistry 59 (19), 8941-8954, 2016
822016
5‐Benzylidenethiazolidin‐4‐ones as multitarget inhibitors of bacterial Mur ligases
T Tomašić, N Zidar, A Kovač, S Turk, M Simčič, D Blanot, ...
ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 286-295, 2010
732010
Synthesis and antibacterial activity of 5-ylidenethiazolidin-4-ones and 5-benzylidene-4, 6-pyrimidinediones
T Tomašić, N Zidar, M Mueller-Premru, D Kikelj, LP Mašič
European journal of medicinal chemistry 45 (4), 1667-1672, 2010
702010
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted†…
A Šmelcerović, K Tomović, Ž Šmelcerović, Ž Petronijević, G Kocić, ...
European journal of medicinal chemistry 135, 491-516, 2017
672017
ATP-binding site of bacterial enzymes as a target for antibacterial drug design
V Škedelj, T Tomašić, LP Mašič, A Zega
Journal of medicinal chemistry 54 (4), 915-929, 2011
602011
Synthesis and biological evaluation of new glutamic acid-based inhibitors of MurD ligase
T Tomašić, N Zidar, V Rupnik, A Kovač, D Blanot, S Gobec, D Kikelj, ...
Bioorganic & medicinal chemistry letters 19 (1), 153-157, 2009
562009
N-Phenyl-4,5-dibromopyrrolamides and N-Phenylindolamides as ATP Competitive DNA Gyrase B Inhibitors: Design, Synthesis, and Evaluation
N Zidar, H Macut, T Tomasic, M Brvar, S Montalvao, P Tammela, ...
Journal of medicinal chemistry 58 (15), 6179-6194, 2015
512015
Structure-Based Design of a New Series of d-Glutamic Acid Based Inhibitors of Bacterial UDP-N-acetylmuramoyl-l-alanine:d-glutamate Ligase (MurD)
T Tomašić, N Zidar, R Sink, A Kovač, D Blanot, C Contreras-Martel, ...
Journal of medicinal chemistry 54 (13), 4600-4610, 2011
512011
New 5-benzylidenethiazolidin-4-one inhibitors of bacterial MurD ligase: design, synthesis, crystal structures, and biological evaluation
N Zidar, T Tomašić, R Šink, A Kovač, D Patin, D Blanot, ...
European journal of medicinal chemistry 46 (11), 5512-5523, 2011
492011
Efflux pump inhibitors of clinically relevant multidrug resistant bacteria
A Lamut, L Peterlin Mašič, D Kikelj, T Tomašič
Medicinal research reviews 39 (6), 2460-2504, 2019
452019
Novel 2-thioxothiazolidin-4-one inhibitors of bacterial MurD ligase targeting D-Glu-and diphosphate-binding sites
T Tomašić, A Kovač, M Simčič, D Blanot, SG Grdadolnik, S Gobec, ...
European journal of medicinal chemistry 46 (9), 3964-3975, 2011
452011
Synthesis and evaluation of N-phenylpyrrolamides as DNA gyrase B inhibitors
M Durcik, PSM Tammela, M BarančokovŠ, T Tomašič, J Ilaš, D Kikelj, ...
ChemMedChem: chemistry enabling drug discovery., 2018
422018
Dual Inhibitor of MurD and MurE Ligases from Escherichia coli and Staphylococcus aureus
T Tomašić, R Šink, N Zidar, A Fic, C Contreras-Martel, A Dessen, ...
ACS medicinal chemistry letters 3 (8), 626-630, 2012
422012
Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors
Ž Jakopin, J Ilaš, M BarančokovŠ, M Brvar, P Tammela, MS Dolenc, ...
European journal of medicinal chemistry 130, 171-184, 2017
402017
Design, synthesis and biological evaluation of 4, 5-dibromo-N-(thiazol-2-yl)-1H-pyrrole-2-carboxamide derivatives as novel DNA gyrase inhibitors
T Tomašič, M Mirt, M BarančokovŠ, J Ilaš, N Zidar, P Tammela, D Kikelj
Bioorganic & medicinal chemistry 25 (1), 338-349, 2017
402017
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