Ziga Jakopin
Ziga Jakopin
Professor of Medicinal Chemistry, Faculty of Pharmacy, University of Ljubljana
Verified email at ffa.uni-lj.si
Cited by
Cited by
Structural features of subtype-selective EP receptor modulators
T Markovič, Ž Jakopin, MS Dolenc, I Mlinarič-Raščan
Drug discovery today 22 (1), 57-71, 2017
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
A Noto, C De Vitis, ME Pisanu, G Roscilli, G Ricci, A Catizone, ...
Oncogene 36 (32), 4573-4584, 2017
Recent advances in the synthesis of 1, 2, 4-and 1, 3, 4-oxadiazoles
Z Jakopin, MS Dolenc
Current organic chemistry 12 (10), 850-898, 2008
Blockade of Stearoyl-CoA-desaturase 1 activity reverts resistance to cisplatin in lung cancer stem cells
ME Pisanu, A Noto, C De Vitis, S Morrone, G Scognamiglio, G Botti, ...
Cancer letters 406, 93-104, 2017
Xanthine oxidase inhibitors beyond allopurinol and febuxostat; an overview and selection of potential leads based on in silico calculated physico-chemical properties, predicted …
A Šmelcerović, K Tomović, Ž Šmelcerović, Ž Petronijević, G Kocić, ...
European journal of medicinal chemistry 135, 491-516, 2017
3,4-Dihydro-2H-1,4-benzoxazine Derivatives Combining Thrombin Inhibitory and Glycoprotein IIb/IIIa Receptor Antagonistic Activity as a Novel Class of …
J Ilaš, Z Jakopin, T Borštnar, M Stegnar, D Kikelj
Journal of medicinal chemistry 51 (18), 5617-5629, 2008
Ferritin heavy chain is a negative regulator of ovarian cancer stem cell expansion and epithelial to mesenchymal transition
N Lobello, F Biamonte, ME Pisanu, MC Faniello, Ž Jakopin, E Chiarella, ...
Oncotarget 7 (38), 62019, 2016
Nucleotide-binding oligomerization domain (NOD) inhibitors: a rational approach toward inhibition of NOD signaling pathway
Z Jakopin
Journal of medicinal chemistry 57 (16), 6897-6918, 2014
Synthesis of 3, 5-disubstituted 1, 2, 4-oxadiazoles as peptidomimetic building blocks
Ž Jakopin, R Roškar, MS Dolenc
Tetrahedron letters 48 (8), 1465-1468, 2007
Discovery of substituted oxadiazoles as a novel scaffold for DNA gyrase inhibitors
Ž Jakopin, J Ilaš, M Barančoková, M Brvar, P Tammela, MS Dolenc, ...
European journal of medicinal chemistry 130, 171-184, 2017
Advances in the chemistry of saccharins: From synthetic novelties towards biologically active compounds
Z Jakopin, MS Dolenc
Current medicinal chemistry 17 (7), 651-671, 2010
Murabutide revisited: a review of its pleiotropic biological effects
Z Jakopin
Current medicinal chemistry 20 (16), 2068-2079, 2013
Inhibition of Stearoyl-CoA desaturase 1 reverts BRAF and MEK inhibition-induced selection of cancer stem cells in BRAF-mutated melanoma
ME Pisanu, M Maugeri-Saccà, L Fattore, S Bruschini, C De Vitis, E Tabbì, ...
Journal of Experimental & Clinical Cancer Research 37 (1), 1-17, 2018
Synthesis of conformationally constrained γ-d-glutamyl-meso-diaminopimelic acid derivatives as ligands of nucleotide-binding oligomerization domain protein 1 (Nod1)
Ž Jakopin, M Gobec, J Kodela, T Hazdovac, I Mlinarič-Raščan, MS Dolenc
European journal of medicinal chemistry 69, 232-243, 2013
Antioxidant and anti-inflammatory properties of 1, 2, 4-oxadiazole analogs of resveratrol
M Gobec, T Tomašič, T Markovič, I Mlinarič-Raščan, MS Dolenc, ...
Chemico-biological interactions 240, 200-207, 2015
Immunomodulatory properties of novel nucleotide oligomerization domain 2 (Nod2) agonistic desmuramyldipeptides
Z Jakopin, M Gobec, I Mlinarič-Raščan, M Sollner Dolenc
Journal of medicinal chemistry 55 (14), 6478-6488, 2012
Inhibition of biofilm formation by conformationally constrained indole-based analogues of the marine alkaloid oroidin
Ž Hodnik, JM Łoś, A Žula, N Zidar, Ž Jakopin, M Łoś, MS Dolenc, J Ilaš, ...
Bioorganic & medicinal chemistry letters 24 (11), 2530-2534, 2014
Structural requirements of acylated Gly-l-Ala-d-Glu analogs for activation of the innate immune receptor NOD2
M Gobec, I Mlinarič-Raščan, MS Dolenc, Ž Jakopin
European journal of medicinal chemistry 116, 1-12, 2016
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
V Schijns, A Fernández‐Tejada, Ž Barjaktarović, I Bouzalas, J Brimnes, ...
Immunological reviews 296 (1), 169-190, 2020
Substituted 4-phenyl-2-aminoimidazoles and 4-phenyl-4, 5-dihydro-2-aminoimidazoles as voltage-gated sodium channel modulators
N Zidar, Ž Jakopin, DJ Madge, F Chan, J Tytgat, S Peigneur, MS Dolenc, ...
European journal of medicinal chemistry 74, 23-30, 2014
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