| Synthesis of novel sulfonamide-1, 2, 4-triazoles, 1, 3, 4-thiadiazoles and 1, 3, 4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and … P Zoumpoulakis, C Camoutsis, G Pairas, M Soković, J Glamočlija, ... Bioorganic & medicinal chemistry 20 (4), 1569-1583, 2012 | 248 | 2012 |
| Structural features of angiotensin-I converting enzyme catalytic sites: conformational studies in solution, homology models and comparison with other zinc metallopeptidases GA Spyroulias, AS Galanis, G Pairas, E Manessi-Zoupa, P Cordopatis Current topics in medicinal chemistry 4 (4), 403-429, 2004 | 53 | 2004 |
| The Isoxazole Ring and Its N‐Oxide: A Privileged Core Structure in Neuropsychiatric Therapeutics GN Pairas, F Perperopoulou, PG Tsoungas, G Varvounis ChemMedChem 12 (6), 408-419, 2017 | 51 | 2017 |
| Rational design, synthesis, and in vivo evaluation of the antileukemic activity of six new alkylating steroidal esters AI Koutsourea, MA Fousteris, ES Arsenou, A Papageorgiou, GN Pairas, ... Bioorganic & medicinal chemistry 16 (9), 5207-5215, 2008 | 45 | 2008 |
| Structural studies and cytotoxicity assays of “aggregation‐prone” IAPP8–16 and its non‐amyloidogenic variants suggest its important role in fibrillogenesis and … NN Louros, PL Tsiolaki, AA Zompra, EV Pappa, V Magafa, G Pairas, ... Peptide Science 104 (3), 196-205, 2015 | 22 | 2015 |
| Monitoring the structural consequences of Phe12→d‐Phe and Leu15→Aib substitution in human/rat corticotropin releasing hormone: Implications for design of … GA Spyroulias, S Papazacharias, G Pairas, P Cordopatis European journal of biochemistry 269 (24), 6009-6019, 2002 | 22 | 2002 |
| H‐Bond: Τhe Chemistry‐Biology H‐Bridge GN Pairas, PG Tsoungas ChemistrySelect 1 (15), 4520-4532, 2016 | 18 | 2016 |
| Enzymatic stability, solution structure, and antiproliferative effect on prostate cancer cells of leuprolide and new gonadotropin‐releasing hormone peptide analogs EV Pappa, AA Zompra, Z Spyranti, Z Diamantopoulou, G Pairas, ... Peptide Science 96 (3), 260-272, 2011 | 17 | 2011 |
| On the formation of 4-[N, N-bis (2-chloroethyl) amino] phenyl acetic acid esters of hecogenin and aza-homo-hecogenin and their antileukemic activity C Camoutsis, D Trafalis, G Pairas, A Papageorgiou Il Farmaco 60 (10), 826-829, 2005 | 17 | 2005 |
| Cytogenetic and antineoplastic effects by newly synthesised steroidal alkylators in lymphocytic leukaemia P388 cells in vivo C Mourelatos, D Kareli, E Dafa, M Argyraki, A Koutsourea, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 746 (1), 1-6, 2012 | 15 | 2012 |
| Structure–activity studies of lGnRH‐III through rational amino acid substitution and NMR conformational studies EV Pappa, AA Zompra, Z Diamantopoulou, Z Spyranti, G Pairas, ... Peptide Science 98 (6), 525-534, 2012 | 15 | 2012 |
| Synthesis, in vivo antileukemic evaluation and comparative study of novel 5α-7-keto steroidal esters of chlorambucil and its active metabolite AI Koutsourea, MA Fousteris, ES Arsenou, A Papageorgiou, GN Pairas, ... in vivo 22 (3), 345-352, 2008 | 15 | 2008 |
| Steroidal esters of the aromatic nitrogen mustard 2-[4-N, N-bis (2-chloroethyl) amino-phenyl] butanoic acid (2-PHE-BU): synthesis and in-vivo biological evaluation IC Papaconstantinou, MA Fousteris, AI Koutsourea, GN Pairas, ... Anti-cancer drugs 24 (1), 52-65, 2013 | 14 | 2013 |
| Zinc binding in peptide models of angiotensin‐I converting enzyme active sites studied through 1H‐NMR and chemical shift perturbation mapping AS Galanis, GA Spyroulias, R Pierattelli, A Tzakos, A Troganis, ... Biopolymers: Original Research on Biomolecules 69 (2), 244-252, 2003 | 14 | 2003 |
| Xanthones in heterocyclic synthesis: An efficient and general route for the synthesis of regioselectively substituted phthalazines Y Gardikis, PG Tsoungas, C Potamitis, M Zervou, G Pairas, P Cordopatis Heterocycles 83 (6), 1291-1302, 2011 | 13 | 2011 |
| Synthesis, structural study and topological analysis of Zn/Aib and Aib-based small peptide complexes (H-Aib-OH= α-aminoisobutyric acid) E Katsoulakou, GS Papaefstathiou, KF Konidaris, G Pairas, ... Polyhedron 28 (15), 3387-3399, 2009 | 13 | 2009 |
| Synthesis and cytogenetic studies of structure–biological activity relationship of esters of Hecogenin and aza-homo-Hecogenin with N, N-bis (2-chloroethyl) aminocinnamic acid … C Camoutsis, D Mourelatos, G Pairas, E Mioglou, C Gasparinatou, ... Steroids 70 (9), 586-593, 2005 | 12 | 2005 |
| Cytogenetic and antineoplastic effects of modified steroidal alkylators I Karapidaki, A Papageorgiou, G Geromichalos, M Fousteris, ... Genetic Testing and Molecular Biomarkers 14 (1), 93-97, 2010 | 10 | 2010 |
| A new route for the synthesis of steroidal esters of carboxylic derivatives of N, N-bis (2-chloroethyl) aniline with DCC G Pairas, C Camoutsis, P Catsoulacos European journal of medicinal chemistry 20 (3), 287-288, 1985 | 10 | 1985 |
| NMR conformational properties of an Anthrax Lethal Factor domain studied by multiple amino acid-selective labeling DJ Vourtsis, CT Chasapis, G Pairas, D Bentrop, GA Spyroulias Biochemical and Biophysical Research Communications 450 (1), 335-340, 2014 | 9 | 2014 |
Georgios A. SpyrouliasProfessor, University of Patras, Department of PharmacyПідтверджена електронна адреса в upatras.gr
