Stanislav Gobec
Stanislav Gobec
Faculty of Pharmacy, University of Ljubljana
Verified email at ffa.uni-lj.si - Homepage
Title
Cited by
Cited by
Year
Cytoplasmic steps of peptidoglycan biosynthesis
H Barreteau, A Kovač, A Boniface, M Sova, S Gobec, D Blanot
FEMS microbiology reviews 32 (2), 168-207, 2008
6912008
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
B Brus, U Kosak, S Turk, A Pislar, N Coquelle, J Kos, J Stojan, JP Colletier, ...
Journal of medicinal chemistry 57 (19), 8167-8179, 2014
1912014
Inhibitors of cathepsin B
R Frlan, S Gobec
Current medicinal chemistry 13 (19), 2309-2327, 2006
1442006
Discovery of novel 5-benzylidenerhodanine and 5-benzylidenethiazolidine-2, 4-dione inhibitors of MurD ligase
N Zidar, T Tomašić, R Sink, V Rupnik, A Kovac, S Turk, D Patin, D Blanot, ...
Journal of medicinal chemistry 53 (18), 6584-6594, 2010
1062010
Inhibitors of 17β-hydroxysteroid dehydrogenase type 1
S Gobec, P Brozic, TL Rizner
Current medicinal chemistry 15 (2), 137-150, 2008
1012008
False positives in the early stages of drug discovery
R Sink, S Gobec, S Pecar, A Zega
Current medicinal chemistry 17 (34), 4231-4255, 2010
932010
Structural and functional characterization of enantiomeric glutamic acid derivatives as potential transition state analogue inhibitors of MurD ligase
M Kotnik, J Humljan, C Contreras-Martel, M Oblak, K Kristan, M Hervé, ...
Journal of molecular biology 370 (1), 107-115, 2007
902007
Endocrine Disruptome An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding
K Kolšek, J Mavri, M Sollner Dolenc, S Gobec, S Turk
Journal of chemical information and modeling 54 (4), 1254-1267, 2014
872014
Structural characterization and biological evaluation of a clioquinol–ruthenium complex with copper-independent antileukaemic activity
M Gobec, J Kljun, I Sosič, I Mlinarič-Raščan, M Uršič, S Gobec, I Turel
Dalton Transactions 43 (24), 9045-9051, 2014
822014
Novel mechanism of cathepsin B inhibition by antibiotic nitroxoline and related compounds
B Mirković, M Renko, S Turk, I Sosič, Z Jevnikar, N Obermajer, D Turk, ...
ChemMedChem 6 (8), 1351-1356, 2011
792011
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
U Košak, B Brus, D Knez, R Šink, S Žakelj, J Trontelj, A Pišlar, J Šlenc, ...
Scientific reports 6 (1), 1-16, 2016
782016
Novel Naphthalene-N-sulfonyl-d-glutamic Acid Derivatives as Inhibitors of MurD, a Key Peptidoglycan Biosynthesis Enzyme,
J Humljan, M Kotnik, C Contreras-Martel, D Blanot, U Urleb, A Dessen, ...
Journal of medicinal chemistry 51 (23), 7486-7494, 2008
752008
The magic of crystal structure-based inhibitor optimization: development of a butyrylcholinesterase inhibitor with picomolar affinity and in vivo activity
U Kosak, B Brus, D Knez, S Zakelj, J Trontelj, A Pislar, R Sink, M Jukic, ...
Journal of medicinal chemistry 61 (1), 119-139, 2018
732018
5‐Benzylidenethiazolidin‐4‐ones as multitarget inhibitors of bacterial Mur ligases
T Tomašić, N Zidar, A Kovač, S Turk, M Simčič, D Blanot, ...
ChemMedChem: Chemistry Enabling Drug Discovery 5 (2), 286-295, 2010
732010
Discovery of novel benzene 1, 3-dicarboxylic acid inhibitors of bacterial MurD and MurE ligases by structure-based virtual screening approach
A Perdih, A Kovač, G Wolber, D Blanot, S Gobec, T Solmajer
Bioorganic & medicinal chemistry letters 19 (10), 2668-2673, 2009
732009
Inhibitors of the peptidoglycan biosynthesis enzymes MurA-F
M Hrast, I Sosič, R Šink, S Gobec
Bioorganic chemistry 55, 2-15, 2014
712014
Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta …
D Panek, A Więckowska, T Wichur, M Bajda, J Godyń, J Jończyk, K Mika, ...
European journal of medicinal chemistry 125, 676-695, 2017
672017
Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure–activity relationships of nitroxoline derivatives
I Sosič, B Mirkovic, K Arenz, B Stefane, J Kos, S Gobec
Journal of medicinal chemistry 56 (2), 521-533, 2013
672013
Design, synthesis and structure–activity relationships of new phosphinate inhibitors of MurD
K Štrancar, D Blanot, S Gobec
Bioorganic & medicinal chemistry letters 16 (2), 343-348, 2006
672006
A new approach towards peptidosulfonamides: synthesis of potential inhibitors of bacterial peptidoglycan biosynthesis enzymes MurD and MurE
J Humljan, M Kotnik, A Boniface, T Šolmajer, U Urleb, D Blanot, S Gobec
Tetrahedron 62 (47), 10980-10988, 2006
662006
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