Plasma cells require autophagy for sustainable immunoglobulin production N Pengo, M Scolari, L Oliva, E Milan, F Mainoldi, A Raimondi, C Fagioli, ... Nature immunology 14 (3), 298-305, 2013 | 435 | 2013 |
The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition G Bianchi, L Oliva, P Cascio, N Pengo, F Fontana, F Cerruti, A Orsi, ... Blood, The Journal of the American Society of Hematology 113 (13), 3040-3049, 2009 | 272 | 2009 |
Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells A Agrotis, N Pengo, JJ Burden, R Ketteler Autophagy 15 (6), 976-997, 2019 | 167 | 2019 |
A reversible phospho-switch mediated by ULK1 regulates the activity of autophagy protease ATG4B N Pengo, A Agrotis, K Prak, J Jones, R Ketteler Nature communications 8 (1), 294, 2017 | 132 | 2017 |
CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells S Masciarelli, AM Fra, N Pengo, M Bertolotti, S Cenci, C Fagioli, D Ron, ... Molecular immunology 47 (6), 1356-1365, 2010 | 81 | 2010 |
Production of H2O2 in the Endoplasmic Reticulum Promotes In Vivo Disulfide Bond Formation É Margittai, P Löw, I Stiller, A Greco, JM Garcia-Manteiga, N Pengo, ... Antioxidants & Redox Signaling 16 (10), 1088-1099, 2012 | 30 | 2012 |
A new fluorogenic peptide determines proteasome activity in single cells SAM Urru, P Veglianese, A De Luigi, E Fumagalli, E Erba, ... Journal of medicinal chemistry 53 (20), 7452-7460, 2010 | 25 | 2010 |
Identification of kinases and phosphatases that regulate ATG4B activity by siRNA and small molecule screening in cells N Pengo, K Prak, JR Costa, C Luft, A Agrotis, J Freeman, CA Gewinner, ... Frontiers in Cell and Developmental Biology 6, 148, 2018 | 22 | 2018 |
The role of autophagy in plasma cell ontogenesis N Pengo, S Cenci Autophagy 9 (6), 942-944, 2013 | 21 | 2013 |
Benzobisthiazoles represent a novel scaffold for kinase inhibitors of CLK family members K Prak, J Kriston-Vizi, AWE Chan, C Luft, JR Costa, N Pengo, R Ketteler Biochemistry 55 (3), 608-617, 2016 | 16 | 2016 |
Proteotoxic stress and cell lifespan control S Cenci, N Pengo, R Sitia Molecules and Cells 26 (4), 323-328, 2008 | 14 | 2008 |
Proteasome activity and stress in light chain amyloidosis L Oliva, N Pengo, G Palladini, P Cascio, E Pasqualetto, G Merlini, R Sitia, ... Amyloid 17, 99-99, 2010 | 11 | 2010 |
Targeting Ara h 2 with human‐derived monoclonal antibodies prevents peanut‐induced anaphylaxis in mice M Paolucci, N Wuillemin, V Homère, D Bieli, A Köhli, B Ballmer‐Weber, ... Allergy 78 (6), 1605-1614, 2023 | 9 | 2023 |
Assessing proteostasis and proteasome stress in light chain amyloidosis L Oliva, G Palladini, F Cerruti, N Pengo, P Cascio, G Merlini, R Sitia, ... Blood 116 (21), 3992, 2010 | 9 | 2010 |
Investigating vulnerability to proteasome inhibition in primary light chain amyloidosis L Oliva, F Cerruti, G Palladini, U Orfanelli, N Pengo, P Cascio, P Rognoni, ... From Misfolded Proteins to Well-Designed Treatment, 31-32, 2012 | 5 | 2012 |
Strain matters in mouse models of peanut‐allergic anaphylaxis: Systemic IgE‐dependent and Ara h 2‐dominant sensitization in C3H mice M Paolucci, V Homère, Y Waeckerle‐Men, N Wuillemin, D Bieli, N Pengo, ... Clinical & Experimental Allergy 53 (5), 550-560, 2023 | 4 | 2023 |
Antibodies as drugs—a Keystone Symposia report J Cable, EO Saphire, AC Hayday, TD Wiltshire, JJ Mousa, DP Humphreys, ... Annals of the New York Academy of Sciences 1519 (1), 153-166, 2023 | 2 | 2023 |
Anti-allergen monoclonal antibodies for the treatment of allergies N Pengo, N Wuillemin, D Bieli, P Gasser Allergo Journal International 32 (7), 289-295, 2023 | 1 | 2023 |
The ASC inflammasome adapter controls the severity of inflammation-related AA amyloidosis M Losa, M Emmenegger, P De Rossi, PM Schuerch, T Serdiuk, N Pengo, ... | 1 | 2021 |
Proteasome stress causes apoptotic sensitivity of multiple myeloma cells to proteasome inhibition G Bianchi, L Oliva, P Cascio, N Pengo, A Orsi, F Fontana, E Pasqualetto, ... Blood, The Journal of the American Society of Hematology 112 (11), 247-247, 2008 | 1 | 2008 |