| A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib) relationships among protein conformation, inhibitor off-rate, and receptor activity in … ER Wood, AT Truesdale, OB McDonald, D Yuan, A Hassell, SH Dickerson, ... Cancer research 64 (18), 6652-6659, 2004 | 1333 | 2004 |
| The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in … DW Rusnak, K Lackey, K Affleck, ER Wood, KJ Alligood, N Rhodes, ... Molecular cancer therapeutics 1 (2), 85-94, 2001 | 957 | 2001 |
| Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and … JB Weinberg, MA Misukonis, PJ Shami, SN Mason, DL Sauls, WA Dittman, ... | 530 | 1995 |
| The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr … JB Weinberg, DL Granger, DS Pisetsky, MF Seldin, MA Misukonis, ... The Journal of experimental medicine 179 (2), 651-660, 1994 | 521 | 1994 |
| The characterization of novel, dual ErbB-2/EGFR, tyrosine kinase inhibitors: potential therapy for cancer DW Rusnak, K Affleck, SG Cockerill, C Stubberfield, R Harris, M Page, ... Cancer research 61 (19), 7196-7203, 2001 | 409 | 2001 |
| Characterization of an Akt kinase inhibitor with potent pharmacodynamic and antitumor activity N Rhodes, DA Heerding, DR Duckett, DJ Eberwein, VB Knick, TJ Lansing, ... Cancer research 68 (7), 2366-2374, 2008 | 341 | 2008 |
| ScII: an abundant chromosome scaffold protein is a member of a family of putative ATPases with an unusual predicted tertiary structure. N Saitoh, IG Goldberg, ER Wood, WC Earnshaw The Journal of cell biology 127 (2), 303-318, 1994 | 332 | 1994 |
| The discovery of potent cRaf1 kinase inhibitors K Lackey, M Cory, R Davis, SV Frye, PA Harris, RN Hunter, DK Jung, ... Bioorganic & medicinal chemistry letters 10 (3), 223-226, 2000 | 293 | 2000 |
| Purification and cDNA sequence of an inducible nitric oxide synthase from a human tumor cell line PA Sherman, VE Laubach, BR Reep, ER Wood Biochemistry 32 (43), 11600-11605, 1993 | 253 | 1993 |
| Mitotic chromatin condensation in vitro using somatic cell extracts and nuclei with variable levels of endogenous topoisomerase II. ER Wood, WC Earnshaw The Journal of cell biology 111 (6), 2839-2850, 1990 | 216 | 1990 |
| Optimization and SAR for dual ErbB-1/ErbB-2 tyrosine kinase inhibition in the 6-furanylquinazoline series KG Petrov, YM Zhang, M Carter, GS Cockerill, S Dickerson, CA Gauthier, ... Bioorganic & medicinal chemistry letters 16 (17), 4686-4691, 2006 | 213 | 2006 |
| Identification of 4-(2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a … DA Heerding, N Rhodes, JD Leber, TJ Clark, RM Keenan, LV Lafrance, ... Journal of medicinal chemistry 51 (18), 5663-5679, 2008 | 175 | 2008 |
| Hepatocytes and macrophages express an identical cytokine-inducible nitric oxide synthase gene ER Wood, H Berger, PA Sherman, EG Lapetina Biochemical and biophysical research communications 191 (3), 767-774, 1993 | 169 | 1993 |
| Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles ER Wood, L Kuyper, KG Petrov, RN Hunter III, PA Harris, K Lackey Bioorganic & medicinal chemistry letters 14 (4), 953-957, 2004 | 149 | 2004 |
| Purification and characterization of the constitutive nitric-oxide synthase from human placenta EP Garvey, JV Tuttle, K Covington, BM Merrill, ER Wood, SA Baylis, ... Archives of biochemistry and biophysics 311 (2), 235-241, 1994 | 138 | 1994 |
| 6-Ethynylthieno [3, 2-d]-and 6-ethynylthieno [2, 3-d] pyrimidin-4-anilines as tunable covalent modifiers of ErbB kinases ER Wood, LM Shewchuk, B Ellis, P Brignola, RL Brashear, TR Caferro, ... Proceedings of the National Academy of Sciences 105 (8), 2773-2778, 2008 | 132 | 2008 |
| Thienopyrimidine-based dual EGFR/ErbB-2 inhibitors TR Rheault, TR Caferro, SH Dickerson, KH Donaldson, MD Gaul, ... Bioorganic & medicinal chemistry letters 19 (3), 817-820, 2009 | 101 | 2009 |
| Expression of a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase-Gr, in rat thymus. MV Frangakis, T Chatila, ER Wood, N Sahyoun Journal of Biological Chemistry 266 (26), 17592-17596, 1991 | 92 | 1991 |
| A scintillation proximity assay for the Raf/MEK/ERK kinase cascade: high-throughput screening and identification of selective enzyme inhibitors OB McDonald, WJ Chen, B Ellis, C Hoffman, L Overton, M Rink, A Smith, ... Analytical biochemistry 268 (2), 318-329, 1999 | 91 | 1999 |
| Association of phosphorylated insulin-like growth factor-I receptor with the SH2 domains of phosphatidylinositol 3-kinase p85. K Yamamoto, D Altschuler, E Wood, K Horlick, S Jacobs, EG Lapetina Journal of Biological Chemistry 267 (16), 11337-11343, 1992 | 90 | 1992 |
