Jennifer Doudna
Jennifer Doudna
Professor of Molecular and Cell Biology and Chemistry, UC Berkeley
Підтверджена електронна адреса в berkeley.edu
НазваПосиланняРік
A programmable dual-RNA–guided DNA endonuclease in adaptive bacterial immunity
M Jinek, K Chylinski, I Fonfara, M Hauer, JA Doudna, E Charpentier
Science 337 (6096), 816-821, 2012
65722012
The new frontier of genome engineering with CRISPR-Cas9
JA Doudna, E Charpentier
Science 346 (6213), 1258096, 2014
23962014
Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression
LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ...
Cell 152 (5), 1173-1183, 2013
22242013
CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes
LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ...
Cell 154 (2), 442-451, 2013
15882013
Crystal structure of a group I ribozyme domain: principles of RNA packing
JH Cate, AR Gooding, E Podell, K Zhou, BL Golden, CE Kundrot, ...
Science 273 (5282), 1678-1685, 1996
14511996
RNA-programmed genome editing in human cells
M Jinek, A East, A Cheng, S Lin, E Ma, J Doudna
elife 2, e00471, 2013
14392013
RNA-guided genetic silencing systems in bacteria and archaea
B Wiedenheft, SH Sternberg, JA Doudna
Nature 482 (7385), 331, 2012
14132012
High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity
V Pattanayak, S Lin, JP Guilinger, E Ma, JA Doudna, DR Liu
Nature biotechnology 31 (9), 839, 2013
9512013
Structural basis for double-stranded RNA processing by Dicer
IJ MacRae, K Zhou, F Li, A Repic, AN Brooks, WZ Cande, PD Adams, ...
Science 311 (5758), 195-198, 2006
9362006
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
SH Sternberg, S Redding, M Jinek, EC Greene, JA Doudna
Nature 507 (7490), 62, 2014
8802014
Crystal structure of a hepatitis delta virus ribozyme
AR Ferré-D'Amaré, K Zhou, JA Doudna
Nature 395 (6702), 567, 1998
8111998
The chemical repertoire of natural ribozymes
JA Doudna, TR Cech
Nature 418 (6894), 222, 2002
7892002
A three-dimensional view of the molecular machinery of RNA interference
M Jinek, JA Doudna
nature 457 (7228), 405, 2008
7372008
Structures of Cas9 endonucleases reveal RNA-mediated conformational activation
M Jinek, F Jiang, DW Taylor, SH Sternberg, E Kaya, E Ma, C Anders, ...
Science 343 (6176), 1247997, 2014
5882014
Molecular mechanisms of RNA interference
RC Wilson, JA Doudna
Annual review of biophysics 42, 217-239, 2013
5722013
Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit
CMT Spahn, JS Kieft, RA Grassucci, PA Penczek, K Zhou, JA Doudna, ...
Science 291 (5510), 1959-1962, 2001
5662001
Sequence-and structure-specific RNA processing by a CRISPR endonuclease
RE Haurwitz, M Jinek, B Wiedenheft, K Zhou, JA Doudna
Science 329 (5997), 1355-1358, 2010
5482010
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
S Lin, BT Staahl, RK Alla, JA Doudna
elife 3, e04766, 2014
4812014
A prudent path forward for genomic engineering and germline gene modification
D Baltimore, P Berg, M Botchan, D Carroll, RA Charo, G Church, JE Corn, ...
Science 348 (6230), 36-38, 2015
4692015
Biology and applications of CRISPR systems: harnessing nature’s toolbox for genome engineering
AV Wright, JK Nuñez, JA Doudna
Cell 164 (1-2), 29-44, 2016
4642016
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