Direct conversion of human fibroblasts to dopaminergic neurons U Pfisterer, A Kirkeby, O Torper, J Wood, J Nelander, A Dufour, ... Proceedings of the National Academy of Sciences 108 (25), 10343-10348, 2011 | 900 | 2011 |
Generation of regionally specified neural progenitors and functional neurons from human embryonic stem cells under defined conditions A Kirkeby, S Grealish, DA Wolf, J Nelander, J Wood, M Lundblad, ... Cell reports 1 (6), 703-714, 2012 | 738 | 2012 |
Human iPS cell-derived dopaminergic neurons function in a primate Parkinson’s disease model T Kikuchi, A Morizane, D Doi, H Magotani, H Onoe, T Hayashi, H Mizuma, ... Nature 548 (7669), 592-596, 2017 | 680 | 2017 |
Generation of induced neurons via direct conversion in vivo O Torper, U Pfisterer, DA Wolf, M Pereira, S Lau, J Jakobsson, ... Proceedings of the National Academy of Sciences 110 (17), 7038-7043, 2013 | 492 | 2013 |
Isolation of human induced pluripotent stem cell-derived dopaminergic progenitors by cell sorting for successful transplantation D Doi, B Samata, M Katsukawa, T Kikuchi, A Morizane, Y Ono, ... Stem cell reports 2 (3), 337-350, 2014 | 480 | 2014 |
Human ESC-derived dopamine neurons show similar preclinical efficacy and potency to fetal neurons when grafted in a rat model of Parkinson’s disease S Grealish, E Diguet, A Kirkeby, B Mattsson, A Heuer, Y Bramoulle, ... Cell stem cell 15 (5), 653-665, 2014 | 470 | 2014 |
Human trials of stem cell-derived dopamine neurons for Parkinson’s disease: dawn of a new era RA Barker, M Parmar, L Studer, J Takahashi Cell stem cell 21 (5), 569-573, 2017 | 350 | 2017 |
Cell-based therapies for Parkinson disease—past insights and future potential RA Barker, J Drouin-Ouellet, M Parmar Nature Reviews Neurology 11 (9), 492-503, 2015 | 346 | 2015 |
Strengths and limitations of the neurosphere culture system JB Jensen, M Parmar Molecular neurobiology 34, 153-161, 2006 | 320 | 2006 |
Predictive markers guide differentiation to improve graft outcome in clinical translation of hESC-based therapy for Parkinson’s disease A Kirkeby, S Nolbrant, K Tiklova, A Heuer, N Kee, T Cardoso, ... Cell stem cell 20 (1), 135-148, 2017 | 277 | 2017 |
The future of stem cell therapies for Parkinson disease M Parmar, S Grealish, C Henchcliffe Nature Reviews Neuroscience 21 (2), 103-115, 2020 | 250 | 2020 |
Generation of high-purity human ventral midbrain dopaminergic progenitors for in vitro maturation and intracerebral transplantation S Nolbrant, A Heuer, M Parmar, A Kirkeby Nature protocols 12 (9), 1962-1979, 2017 | 220 | 2017 |
Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development K Tiklová, ÅK Björklund, L Lahti, A Fiorenzano, S Nolbrant, L Gillberg, ... Nature communications 10 (1), 581, 2019 | 214 | 2019 |
Advances in stem cell research and therapeutic development M De Luca, A Aiuti, G Cossu, M Parmar, G Pellegrini, PG Robey Nature Cell Biology 21 (7), 801-811, 2019 | 200 | 2019 |
Development of the mesencephalic dopaminergic neuron system is compromised in the absence of neurogenin 2 E Andersson, JB Jensen, M Parmar, F Guillemot, A Bjorklund Oxford University Press for The Company of Biologists Limited 133 (3), 507-516, 2006 | 199 | 2006 |
In vivo reprogramming of striatal NG2 glia into functional neurons that integrate into local host circuitry O Torper, DR Ottosson, M Pereira, S Lau, T Cardoso, S Grealish, ... Cell reports 12 (3), 474-481, 2015 | 194 | 2015 |
New approaches for brain repair—from rescue to reprogramming RA Barker, M Götz, M Parmar Nature 557 (7705), 329-334, 2018 | 189 | 2018 |
Identification of embryonic stem cell–derived midbrain dopaminergic neurons for engraftment YM Ganat, EL Calder, S Kriks, J Nelander, EY Tu, F Jia, D Battista, ... The Journal of clinical investigation 122 (8), 2928-2939, 2012 | 173 | 2012 |
Neural grafting in Parkinson’s disease: problems and possibilities P Brundin, RA Barker, M Parmar Progress in brain research 184, 265-294, 2010 | 173 | 2010 |
Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuli D Tornero, O Tsupykov, M Granmo, C Rodriguez, M Grønning-Hansen, ... Brain 140 (3), 692-706, 2017 | 144 | 2017 |