| Mutation allele burden remains unchanged in chronic myelomonocytic leukaemia responding to hypomethylating agents J Merlevede, N Droin, T Qin, K Meldi, K Yoshida, M Morabito, E Chautard, ... Nature communications 7 (1), 10767, 2016 | 225 | 2016 |
| IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response FJ Núñez, FM Mendez, P Kadiyala, MS Alghamri, MG Savelieff, ... Science translational medicine 11 (479), eaaq1427, 2019 | 208 | 2019 |
| Specific molecular signatures predict decitabine response in chronic myelomonocytic leukemia K Meldi, T Qin, F Buchi, N Droin, J Sotzen, JB Micol, D Selimoglu-Buet, ... The Journal of clinical investigation 125 (5), 1857-1872, 2015 | 192 | 2015 |
| Aging human hematopoietic stem cells manifest profound epigenetic reprogramming of enhancers that may predispose to leukemia ER Adelman, HT Huang, A Roisman, A Olsson, A Colaprico, T Qin, ... Cancer discovery 9 (8), 1080-1101, 2019 | 151 | 2019 |
| Epigenetic identity in AML depends on disruption of nonpromoter regulatory elements and is affected by antagonistic effects of mutations in epigenetic modifiers JL Glass, D Hassane, BJ Wouters, H Kunimoto, R Avellino, ... Cancer discovery 7 (8), 868-883, 2017 | 111 | 2017 |
| Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic pontine gliomas C Chung, SR Sweha, D Pratt, B Tamrazi, P Panwalkar, A Banda, J Bayliss, ... Cancer cell 38 (3), 334-349. e9, 2020 | 105 | 2020 |
| Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker SM Rachidi, T Qin, S Sun, WJ Zheng, Z Li PloS one 8 (3), e57911, 2013 | 94 | 2013 |
| DNMT3A Haploinsufficiency Transforms FLT3ITD Myeloproliferative Disease into a Rapid, Spontaneous, and Fully Penetrant Acute Myeloid Leukemia SE Meyer, T Qin, DE Muench, K Masuda, M Venkatasubramanian, E Orr, ... Cancer discovery 6 (5), 501-515, 2016 | 88 | 2016 |
| The role of the histone H3 variant CENPA in prostate cancer AK Saha, R Contreras-Galindo, YS Niknafs, M Iyer, T Qin, ... Journal of Biological Chemistry 295 (25), 8537-8549, 2020 | 55 | 2020 |
| A genome-wide MeSH-based literature mining system predicts implicit gene-to-gene relationships and networks Z Xiang, T Qin, ZS Qin, Y He BMC systems biology 7, 1-15, 2013 | 42 | 2013 |
| Expressed HNSCC variants by HPV-status in a well-characterized Michigan cohort T Qin, Y Zhang, KR Zarins, TR Jones, S Virani, LA Peterson, JB McHugh, ... Scientific reports 8 (1), 11458, 2018 | 39 | 2018 |
| ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization T Qin, B Mullan, R Ravindran, D Messinger, R Siada, JR Cummings, ... Cell reports 38 (2), 2022 | 34 | 2022 |
| Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ... Cancer discovery 13 (11), 2370-2393, 2023 | 26 | 2023 |
| Signaling network prediction by the Ontology Fingerprint enhanced Bayesian network T Qin, LC Tsoi, KJ Sims, X Lu, WJ Zheng BMC systems biology 6, 1-13, 2012 | 24 | 2012 |
| Novel role of ASH1L histone methyltransferase in anaplastic thyroid carcinoma B Xu, T Qin, J Yu, TJ Giordano, MA Sartor, RJ Koenig Journal of Biological Chemistry 295 (26), 8834-8845, 2020 | 23 | 2020 |
| Aging human hematopoietic stem cells manifest profound epigenetic reprogramming of enhancers that may predispose to leukemia. Cancer Discov. 2019; 9: 1080–1101. doi: 10.1158 … ER Adelman, HT Huang, A Roisman, A Olsson, A Colaprico, T Qin, ... CD-18-1474.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 22 | |
| Oncogenic N-Ras and Tet2 haploinsufficiency collaborate to dysregulate hematopoietic stem and progenitor cells X Jin, T Qin, M Zhao, N Bailey, L Liu, K Yang, V Ng, T Higashimoto, ... Blood advances 2 (11), 1259-1271, 2018 | 20 | 2018 |
| DNMT3A haploinsufficiency transforms FLT3ITD myeloproliferative disease into a rapid, spontaneous, and fully penetrant acute myeloid leukemia. Cancer Discov. 2016; 6 (5): 501 … SE Meyer, T Qin, DE Muench, K Masuda, M Venkatasubramanian, E Orr, ... CD-16-0008.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 20 | |
| Epigenetically defined therapeutic targeting in H3. 3G34R/V high-grade gliomas SR Sweha, C Chung, SK Natarajan, P Panwalkar, M Pun, A Ghali, ... Science translational medicine 13 (615), eabf7860, 2021 | 19 | 2021 |
| Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer Y Zhang, J Yu, V Grachtchouk, T Qin, CN Lumeng, MA Sartor, RJ Koenig Oncotarget 8 (4), 5761, 2017 | 18 | 2017 |
Alex Lam TsoiAssistant Professor, University of MichiganПідтверджена електронна адреса в umich.edu
