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Jiawen Chen
Jiawen Chen
Verified email at email.unc.edu
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Year
Estimating genetic nurture with summary statistics of multigenerational genome-wide association studies
Y Wu, X Zhong, Y Lin, Z Zhao, J Chen, B Zheng, JJ Li, JM Fletcher, Q Lu
Proceedings of the National Academy of Sciences 118 (25), e2023184118, 2021
432021
Leveraging base-pair mammalian constraint to understand genetic variation and human disease
PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ...
Science 380 (6643), eabn2937, 2023
372023
TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data
L Huang, JD Rosen, Q Sun, J Chen, MM Wheeler, Y Zhou, YI Min, ...
The American Journal of Human Genetics 109 (6), 1175-1181, 2022
292022
A comprehensive comparison on cell-type composition inference for spatial transcriptomics data
J Chen, W Liu, T Luo, Z Yu, M Jiang, J Wen, GP Gupta, P Giusti, H Zhu, ...
Briefings in Bioinformatics 23 (4), bbac245, 2022
262022
From GWAS variant to function: A study of∼ 148,000 variants for blood cell traits
Q Sun, CA Crowley, L Huang, J Wen, J Chen, EL Bao, PL Auer, G Lettre, ...
Human Genetics and Genomics Advances 3 (1), 2022
182022
Transcriptome-wide transmission disequilibrium analysis identifies novel risk genes for autism spectrum disorder
K Huang, Y Wu, J Shin, Y Zheng, AF Siahpirani, Y Lin, Z Ni, J Chen, J You, ...
PLoS genetics 17 (2), e1009309, 2021
152021
Transcriptome-Wide association study of blood cell traits in African ancestry and Hispanic/Latino populations
J Wen, M Xie, B Rowland, JD Rosen, Q Sun, J Chen, AL Tapia, H Qian, ...
Genes 12 (7), 1049, 2021
122021
MagicalRsq: Machine-learning-based genotype imputation quality calibration
Q Sun, Y Yang, JD Rosen, MZ Jiang, J Chen, W Liu, J Wen, LM Raffield, ...
The American Journal of Human Genetics 109 (11), 1986-1997, 2022
102022
Understanding the function of regulatory DNA interactions in the interpretation of non-coding GWAS variants
W Zhong, W Liu, J Chen, Q Sun, M Hu, Y Li
Frontiers in cell and developmental biology 10, 957292, 2022
102022
Understanding regulatory mechanisms of brain function and disease through 3d genome organization
W Liu, W Zhong, J Chen, B Huang, M Hu, Y Li
Genes 13 (4), 586, 2022
82022
Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-specific effects via GAUDI
Q Sun, BT Rowland, J Chen, AV Mikhaylova, C Avery, U Peters, J Lundin, ...
bioRxiv, 2022.10. 06.511219, 2022
72022
Canonical correlation analysis for multi-omics: Application to cross-cohort analysis
MZ Jiang, F Aguet, K Ardlie, J Chen, E Cornell, D Cruz, P Durda, ...
PLoS genetics 19 (5), e1010517, 2023
52023
Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS
J Chen, T Luo, M Jiang, J Liu, GP Gupta, Y Li
Science Advances 9 (9), eadd9818, 2023
52023
Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
YA Jakubek, Y Zhou, A Stilp, J Bacon, JW Wong, Z Ozcan, D Arnett, ...
Nature genetics 55 (11), 1912-1919, 2023
42023
DeepGWAS: Enhance GWAS Signals for Neuropsychiatric Disorders via Deep Neural Network
Y Li, J Wen, G Li, J Chen, Q Sun, W Liu, W Guan, B Lai, J Szatkiewicz, ...
Research Square, 2023
42023
Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types
J Wen, TM Lagler, Q Sun, Y Yang, J Chen, Y Harigaya, VG Sankaran, ...
Plos Genetics 18 (1), e1009984, 2022
42022
HPRep: quantifying reproducibility in HiChIP and PLAC-seq datasets
JD Rosen, Y Yang, A Abnousi, J Chen, M Song, IR Jones, Y Shen, M Hu, ...
Current Issues in Molecular Biology 43 (2), 1156-1170, 2021
42021
Gamete simulation improves polygenic transmission disequilibrium analysis
J Chen, J You, Z Zhao, Z Ni, K Huang, Y Wu, JM Fletcher, Q Lu
bioRxiv, 2020.10. 26.355602, 2020
42020
SnapFISH: a computational pipeline to identify chromatin loops from multiplexed DNA FISH data
L Lee, H Yu, BB Jia, A Jussila, C Zhu, J Chen, L Xie, A Hafner, S Mishra, ...
Nature Communications 14 (1), 4873, 2023
22023
HPTAD: A computational method to identify topologically associating domains from HiChIP and PLAC-seq datasets
J Rosen, L Lee, A Abnousi, J Chen, J Wen, M Hu, Y Li
Computational and Structural Biotechnology Journal 21, 931-939, 2023
12023
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