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Onkar Sharma
Onkar Sharma
Boston Children's Hospital
Verified email at childrens.harvard.edu
Title
Cited by
Cited by
Year
Crystal structures of the OmpF porin: function in a colicin translocon
E Yamashita, MV Zhalnina, SD Zakharov, O Sharma, WA Cramer
The EMBO journal 27 (15), 2171-2180, 2008
1752008
Colicin occlusion of OmpF and TolC channels: outer membrane translocons for colicin import
SD Zakharov, VY Eroukova, TI Rokitskaya, MV Zhalnina, O Sharma, ...
Biophysical journal 87 (6), 3901-3911, 2004
962004
Structure of the complex of the colicin E2 R-domain and its BtuB receptor: the outer membrane colicin translocon
O Sharma, E Yamashita, MV Zhalnina, SD Zakharov, KA Datsenko, ...
Journal of Biological Chemistry 282 (32), 23163-23170, 2007
682007
Mobility of BtuB and OmpF in the Escherichia coli outer membrane: implications for dynamic formation of a translocon complex
J Spector, S Zakharov, Y Lill, O Sharma, WA Cramer, K Ritchie
Biophysical journal 99 (12), 3880-3886, 2010
622010
Conformational switching of the diphtheria toxin T domain
MV Rodnin, A Kyrychenko, P Kienker, O Sharma, YO Posokhov, ...
Journal of molecular biology 402 (1), 1-7, 2010
622010
Chemical dissection of protein translocation through the anthrax toxin pore
BL Pentelute, O Sharma, RJ Collier
Angewandte Chemie (International ed. in English) 50 (10), 2294, 2011
582011
Genome‐wide screens: novel mechanisms in colicin import and cytotoxicity
O Sharma, KA Datsenko, SC Ess, MV Zhalnina, BL Wanner, WA Cramer
Molecular microbiology 73 (4), 571-585, 2009
512009
On mechanisms of colicin import: the outer membrane quandary
WA Cramer, O Sharma, SD Zakharov
Biochemical Journal 475 (23), 3903-3915, 2018
412018
NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus
O Sharma, M O’Seaghdha, JJ Velarde, MR Wessels
PLoS pathogens 12 (3), e1005468, 2016
412016
The colicin E3 outer membrane translocon: immunity protein release allows interaction of the cytotoxic domain with OmpF porin
SD Zakharov, MV Zhalnina, O Sharma, WA Cramer
Biochemistry 45 (34), 10199-10207, 2006
402006
Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity
D Hancz, E Westerlund, B Bastiat-Sempe, O Sharma, C Valfridsson, ...
MBio 8 (4), 10.1128/mbio. 00756-17, 2017
372017
Replacement of C-terminal histidines uncouples membrane insertion and translocation in diphtheria toxin T-domain
MV Rodnin, A Kyrychenko, P Kienker, O Sharma, M Vargas-Uribe, ...
Biophysical journal 101 (10), L41-L43, 2011
352011
Cellular entry of the diphtheria toxin does not require the formation of the open-channel state by its translocation domain
AS Ladokhin, M Vargas-Uribe, MV Rodnin, C Ghatak, O Sharma
Toxins 9 (10), 299, 2017
192017
Primary events in the colicin translocon: FRET analysis of colicin unfolding initiated by binding to BtuB and OmpF
SD Zakharov, O Sharma, MV Zhalnina, WA Cramer
Biochemistry 47 (48), 12802-12809, 2008
192008
Pathways of colicin import: utilization of BtuB, OmpF porin and the TolC drug-export protein
SD Zakharov, O Sharma, M Zhalnina, E Yamashita, WA Cramer
Biochemical Society Transactions 40 (6), 1463-1468, 2012
172012
Minimum length requirement of the flexible N-terminal translocation subdomain of colicin E3
O Sharma, WA Cramer
Journal of bacteriology 189 (2), 363-368, 2007
142007
Membrane proteins in four acts: Function precedes structure determination
WA Cramer, SD Zakharov, SS Hasan, H Zhang, D Baniulis, MV Zhalnina, ...
Methods 55 (4), 415-420, 2011
112011
Colicins: Bacterial/antibiotic peptides
O Sharma, SD Zakharov, WA Cramer
Handbook of biologically active peptides, 115-123, 2006
102006
Polylysine-mediated translocation of the diphtheria toxin catalytic domain through the anthrax protective antigen pore
O Sharma, RJ Collier
Biochemistry 53 (44), 6934-6940, 2014
82014
Comparison of Various Methods for Determining Functional Activity of the Diphtheria Toxin T-Domain
MV Rodnin, A Kyrychenko, PK Kienker, O Sharma, M Vargas-Uribe, ...
Biophysical Journal 102 (3), 244a-245a, 2012
2012
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