An expanded genome-wide association study of type 2 diabetes in Europeans RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ... Diabetes 66 (11), 2888-2902, 2017 | 717 | 2017 |
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M Van De Bunt, ... Nature genetics 49 (1), 17-26, 2017 | 524 | 2017 |
Structure, function and evolution of multidomain proteins C Vogel, M Bashton, ND Kerrison, C Chothia, SA Teichmann Current opinion in structural biology 14 (2), 208-216, 2004 | 480 | 2004 |
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ... Nature genetics 47 (12), 1415-1425, 2015 | 408 | 2015 |
The link between family history and risk of type 2 diabetes is not explained by anthropometric, lifestyle or genetic risk factors: the EPIC-InterAct study InterAct Consortium robert. scott@ mrc-epid. cam. ac. uk Diabetologia 56, 60-69, 2013 | 408 | 2013 |
Long-term risk of incident type 2 diabetes and measures of overall and regional obesity: the EPIC-InterAct case-cohort study InterAct Consortium PLoS medicine 9 (6), e1001230, 2012 | 253 | 2012 |
Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study C Langenberg, SJ Sharp, PW Franks, RA Scott, P Deloukas, NG Forouhi, ... PLoS medicine 11 (5), e1001647, 2014 | 251 | 2014 |
Human gain-of-function MC4R variants show signaling bias and protect against obesity LA Lotta, J Mokrosiński, EM de Oliveira, C Li, SJ Sharp, J Luan, ... Cell 177 (3), 597-607. e9, 2019 | 230 | 2019 |
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility J Wessel, AY Chu, SM Willems, S Wang, H Yaghootkar, JA Brody, ... Nature communications 6 (1), 5897, 2015 | 225 | 2015 |
Validity of a short questionnaire to assess physical activity in 10 European countries T Peters, S Brage, K Westgate, PW Franks, A Gradmark, MJT Diaz, ... European Journal of Epidemiology 27 (1), 15-25, 2012 | 222 | 2012 |
Design and cohort description of the InterAct Project: an examination of the interaction of genetic and lifestyle factors on the incidence of type 2 diabetes in the EPIC Study C Langenberg, S Sharp, NG Forouhi, PW Franks, MB Schulze, N Kerrison, ... Diabetologia 54 (9), 2272-2282, 2011 | 222 | 2011 |
Genetic predisposition to mosaic Y chromosome loss in blood DJ Thompson, G Genovese, J Halvardson, JC Ulirsch, DJ Wright, C Terao, ... Nature 575 (7784), 652-657, 2019 | 213 | 2019 |
Mapping the proteo-genomic convergence of human diseases M Pietzner, E Wheeler, J Carrasco-Zanini, A Cortes, M Koprulu, ... Science 374 (6569), eabj1541, 2021 | 208 | 2021 |
A Neanderthal OAS1 isoform protects individuals of European ancestry against COVID-19 susceptibility and severity S Zhou, G Butler-Laporte, T Nakanishi, DR Morrison, J Afilalo, M Afilalo, ... Nature medicine 27 (4), 659-667, 2021 | 206 | 2021 |
A large-scale multi-ancestry genome-wide study accounting for smoking behavior identifies multiple significant loci for blood pressure YJ Sung, TW Winkler, L de Las Fuentes, AR Bentley, MR Brown, AT Kraja, ... The American Journal of Human Genetics 102 (3), 375-400, 2018 | 146 | 2018 |
Genetic variants associated with mosaic Y chromosome loss highlight cell cycle genes and overlap with cancer susceptibility DJ Wright, FR Day, ND Kerrison, F Zink, A Cardona, P Sulem, ... Nature genetics 49 (5), 674-679, 2017 | 141 | 2017 |
Genome-wide association analysis in humans links nucleotide metabolism to leukocyte telomere length C Li, S Stoma, LA Lotta, S Warner, E Albrecht, A Allione, PP Arp, L Broer, ... The American Journal of Human Genetics 106 (3), 389-404, 2020 | 140 | 2020 |
Coordinated multitissue transcriptional and plasma metabonomic profiles following acute caloric restriction in mice C Selman, ND Kerrison, A Cooray, MDW Piper, SJ Lingard, RH Barton, ... Physiological genomics 27 (3), 187-200, 2006 | 131 | 2006 |
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease RA Scott, DF Freitag, L Li, AY Chu, P Surendran, R Young, N Grarup, ... Science translational medicine 8 (341), 341ra76-341ra76, 2016 | 122 | 2016 |
Synergistic insights into human health from aptamer-and antibody-based proteomic profiling M Pietzner, E Wheeler, J Carrasco-Zanini, ND Kerrison, E Oerton, ... Nature communications 12 (1), 6822, 2021 | 106 | 2021 |