Adeno-associated virus serotype 9 transduction in the central nervous system of nonhuman primates L Samaranch, EA Salegio, W San Sebastian, AP Kells, KD Foust, ... Human gene therapy 23 (4), 382-389, 2012 | 330 | 2012 |
Long-term evaluation of a phase 1 study of AADC gene therapy for Parkinson's disease G Mittermeyer, CW Christine, KH Rosenbluth, SL Baker, P Starr, P Larson, ... Human gene therapy 23 (4), 377-381, 2012 | 323 | 2012 |
Long-term clinical improvement in MPTP-lesioned primates after gene therapy with AAV-hAADC KS Bankiewicz, J Forsayeth, JL Eberling, R Sanchez-Pernaute, P Pivirotto, ... Molecular Therapy 14 (4), 564-570, 2006 | 317 | 2006 |
An open rectifier potassium channel with two pore domains in tandem cloned from rat cerebellum D Leonoudakis, AT Gray, BD Winegar, CH Kindler, M Harada, DM Taylor, ... Journal of Neuroscience 18 (3), 868-877, 1998 | 297 | 1998 |
Engineering GPCR signaling pathways with RASSLs BR Conklin, EC Hsiao, S Claeysen, A Dumuis, S Srinivasan, ... Nature methods 5 (8), 673-678, 2008 | 293 | 2008 |
Controlling pathological pain by adenovirally driven spinal production of the anti‐inflammatory cytokine, interleukin‐10 ED Milligan, SJ Langer, EM Sloane, L He, J Wieseler‐Frank, K O'Connor, ... European Journal of Neuroscience 21 (8), 2136-2148, 2005 | 261 | 2005 |
Controlling neuropathic pain by adeno-associated virus driven production of the anti-inflammatory cytokine, interleukin-10 ED Milligan, EM Sloane, SJ Langer, PE Cruz, M Chacur, L Spataro, ... Molecular pain 1, 1744-8069-1-9, 2005 | 233 | 2005 |
Axonal transport of adeno-associated viral vectors is serotype-dependent EA Salegio, L Samaranch, AP Kells, G Mittermeyer, W San Sebastian, ... Gene therapy 20 (3), 348-352, 2013 | 190 | 2013 |
Eight years of clinical improvement in MPTP-lesioned primates after gene therapy with AAV2-hAADC P Hadaczek, JL Eberling, P Pivirotto, J Bringas, J Forsayeth, ... Molecular Therapy 18 (8), 1458-1461, 2010 | 186 | 2010 |
TWIK-2, a new weak inward rectifying member of the tandem pore domain potassium channel family RA Chavez, AT Gray, BB Zhao, CH Kindler, MJ Mazurek, Y Mehta, ... Journal of Biological Chemistry 274 (12), 7887-7892, 1999 | 174 | 1999 |
Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates L Samaranch, EA Salegio, W San Sebastian, AP Kells, JR Bringas, ... Human gene therapy 24 (5), 526-532, 2013 | 163 | 2013 |
Efficient gene therapy-based method for the delivery of therapeutics to primate cortex AP Kells, P Hadaczek, D Yin, J Bringas, V Varenika, J Forsayeth, ... Proceedings of the National Academy of Sciences 106 (7), 2407-2411, 2009 | 162 | 2009 |
AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction L Samaranch, W San Sebastian, AP Kells, EA Salegio, G Heller, ... Molecular Therapy 22 (2), 329-337, 2014 | 160 | 2014 |
Interventional MRI-guided putaminal delivery of AAV2-GDNF for a planned clinical trial in Parkinson's disease RM Richardson, AP Kells, KH Rosenbluth, EA Salegio, MS Fiandaca, ... Molecular Therapy 19 (6), 1048-1057, 2011 | 151 | 2011 |
Image-guided convection-enhanced delivery platform in the treatment of neurological diseases MS Fiandaca, JR Forsayeth, PJ Dickinson, KS Bankiewicz Neurotherapeutics 5, 123-127, 2008 | 149 | 2008 |
Assembly of the mammalian muscle acetylcholine receptor in transfected COS cells. Y Gu, JR Forsayeth, S Verrall, XM Yu, ZW Hall The Journal of cell biology 114 (4), 799-807, 1991 | 149 | 1991 |
Convection-enhanced delivery of nanoliposomal CPT-11 (irinotecan) and PEGylated liposomal doxorubicin (Doxil) in rodent intracranial brain tumor xenografts MT Krauze, CO Noble, T Kawaguchi, D Drummond, DB Kirpotin, ... Neuro-oncology 9 (4), 393-403, 2007 | 148 | 2007 |
Regeneration of the MPTP-lesioned dopaminergic system after convection-enhanced delivery of AAV2-GDNF AP Kells, J Eberling, X Su, P Pivirotto, J Bringas, P Hadaczek, WC Narrow, ... Journal of Neuroscience 30 (28), 9567-9577, 2010 | 135 | 2010 |
Canine spontaneous glioma: a translational model system for convection-enhanced delivery PJ Dickinson, RA LeCouteur, RJ Higgins, JR Bringas, RF Larson, ... Neuro-oncology 12 (9), 928-940, 2010 | 132 | 2010 |
Cerebral infusion of AAV9 vector-encoding non-self proteins can elicit cell-mediated immune responses A Ciesielska, P Hadaczek, G Mittermeyer, S Zhou, JF Wright, ... Molecular Therapy 21 (1), 158-166, 2013 | 126 | 2013 |