Jan Näslund
Jan Näslund
Підтверджена електронна адреса в ki.se - Домашня сторінка
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Посилання
Рік
Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline
J Näslund, V Haroutunian, R Mohs, KL Davis, P Davies, P Greengard, ...
Jama 283 (12), 1571-1577, 2000
15402000
The'Arctic'APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation
C Nilsberth, A Westlind-Danielsson, CB Eckman, MM Condron, ...
Nature neuroscience 4 (9), 887, 2001
12802001
Arrest of-amyloid fibril formation by a pentapeptide ligand
LO Tjernberg, J Näslund, F Lindqvist, J Johansson, AR Karlström, ...
Journal of Biological Chemistry 271 (15), 8545-8548, 1996
10681996
Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease
WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ...
J Cell Biol 171 (1), 87-98, 2005
9972005
Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging
J Näslund, A Schierhorn, U Hellman, L Lannfelt, AD Roses, LO Tjernberg, ...
Proceedings of the National Academy of Sciences 91 (18), 8378-8382, 1994
5051994
Controlling amyloid β-peptide fibril formation with protease-stable ligands
LO Tjernberg, C Lilliehöök, DJE Callaway, J Näslund, S Hahne, ...
Journal of Biological Chemistry 272 (19), 12601-12605, 1997
2981997
A nine-transmembrane domain topology for presenilin 1
H Laudon, EM Hansson, K Melén, A Bergman, MR Farmery, B Winblad, ...
Journal of Biological Chemistry 280 (42), 35352-35360, 2005
2432005
Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain
J Näslund, J Thyberg, LO Tjernberg, C Wernstedt, AR Karlström, ...
Neuron 15 (1), 219-228, 1995
2281995
Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid
B Häggqvist, J Näslund, K Sletten, GT Westermark, G Mucchiano, ...
Proceedings of the National Academy of Sciences 96 (15), 8669-8674, 1999
2211999
Partial purification and characterization of γ-secretase from post-mortem human brain
MR Farmery, LO Tjernberg, SE Pursglove, A Bergman, B Winblad, ...
Journal of Biological Chemistry 278 (27), 24277-24284, 2003
1732003
Endogenous proteins controlling amyloid β-peptide polymerization possible implications for β-amyloid formation in the central nervous system and in peripheral tissues
B Bohrmann, L Tjernberg, P Kuner, S Poli, B Levet-Trafit, J Näslund, ...
Journal of Biological Chemistry 274 (23), 15990-15995, 1999
1691999
Amyloid fibril formation by pulmonary surfactant protein C
M Gustafsson, J Thyberg, J Näslund, E Eliasson, J Johansson
FEBS letters 464 (3), 138-142, 1999
1341999
The Alzheimer A beta peptide develops protease resistance in association with its polymerization into fibrils.
C Nordstedt, J Näslund, LO Tjernberg, AR Karlström, J Thyberg, ...
Journal of Biological Chemistry 269 (49), 30773-30776, 1994
1241994
Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease
H Basun, N Bogdanovic, M Ingelsson, O Almkvist, J Näslund, K Axelman, ...
Archives of neurology 65 (4), 499-505, 2008
1102008
A sensitive and quantitative assay for measuring cleavage of presenilin substrates
H Karlström, A Bergman, U Lendahl, J Näslund, J Lundkvist
Journal of Biological Chemistry 277 (9), 6763-6766, 2002
1082002
Controlling polymerization of β-amyloid and prion-derived peptides with synthetic small molecule ligands
P Kuner, B Bohrmann, LO Tjernberg, J Näslund, G Huber, S Celenk, ...
Journal of Biological Chemistry 275 (3), 1673-1678, 2000
1082000
Treatment of alzheimer's disease
L Lannfelt, C Nilsberth, A Westlind-Danielsson, J Näslund
US Patent 7,179,463, 2007
1042007
Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin
A Bergman, EM Hansson, SE Pursglove, MR Farmery, L Lannfelt, ...
Journal of Biological Chemistry 279 (16), 16744-16753, 2004
1042004
Quantification of Alzheimer Amyloid β Peptides Ending at Residues 40 and 42 by Novel ELISA Systems
M Jensen, T Hartmann, B Engvall, R Wang, SN Uljon, K Sennvik, ...
Molecular Medicine 6 (4), 291-302, 2000
972000
γ-Secretase: a complex target for Alzheimer's disease
J Lundkvist, J Näslund
Current opinion in pharmacology 7 (1), 112-118, 2007
742007
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