| Correlation between elevated levels of amyloid β-peptide in the brain and cognitive decline J Näslund, V Haroutunian, R Mohs, KL Davis, P Davies, P Greengard, ... Jama 283 (12), 1571-1577, 2000 | 1719 | 2000 |
| The'Arctic'APP mutation (E693G) causes Alzheimer's disease by enhanced Aβ protofibril formation C Nilsberth, A Westlind-Danielsson, CB Eckman, MM Condron, ... Nature neuroscience 4 (9), 887-893, 2001 | 1508 | 2001 |
| Arrest of-Amyloid Fibril Formation by a Pentapeptide Ligand (∗) LO Tjernberg, J Näslund, F Lindqvist, J Johansson, AR Karlström, ... Journal of Biological Chemistry 271 (15), 8545-8548, 1996 | 1187 | 1996 |
| Macroautophagy—a novel β-amyloid peptide-generating pathway activated in Alzheimer's disease WH Yu, AM Cuervo, A Kumar, CM Peterhoff, SD Schmidt, JH Lee, ... The Journal of cell biology 171 (1), 87-98, 2005 | 1159 | 2005 |
| Relative abundance of Alzheimer A beta amyloid peptide variants in Alzheimer disease and normal aging. J Näslund, A Schierhorn, U Hellman, L Lannfelt, AD Roses, LO Tjernberg, ... Proceedings of the National Academy of Sciences 91 (18), 8378-8382, 1994 | 575 | 1994 |
| Controlling amyloid β-peptide fibril formation with protease-stable ligands LO Tjernberg, C Lilliehöök, DJE Callaway, J Näslund, S Hahne, ... Journal of Biological Chemistry 272 (19), 12601-12605, 1997 | 321 | 1997 |
| A nine-transmembrane domain topology for presenilin 1 H Laudon, EM Hansson, K Melén, A Bergman, MR Farmery, B Winblad, ... Journal of Biological Chemistry 280 (42), 35352-35360, 2005 | 269 | 2005 |
| Medin: an integral fragment of aortic smooth muscle cell-produced lactadherin forms the most common human amyloid BO Häggqvist, J Näslund, K Sletten, GT Westermark, G Mucchiano, ... Proceedings of the National Academy of Sciences 96 (15), 8669-8674, 1999 | 257 | 1999 |
| Characterization of stable complexes involving apolipoprotein E and the amyloid β peptide in Alzheimer's disease brain J Näslund, J Thyberg, LO Tjernberg, C Wernstedt, AR Karlström, ... Neuron 15 (1), 219-228, 1995 | 239 | 1995 |
| Endogenous proteins controlling amyloid β-peptide polymerization: possible implications for β-amyloid formation in the central nervous system and in peripheral tissues B Bohrmann, L Tjernberg, P Kuner, S Poli, B Levet-Trafit, J Näslund, ... Journal of Biological Chemistry 274 (23), 15990-15995, 1999 | 185 | 1999 |
| Partial purification and characterization of γ-secretase from post-mortem human brain MR Farmery, LO Tjernberg, SE Pursglove, A Bergman, B Winblad, ... Journal of Biological Chemistry 278 (27), 24277-24284, 2003 | 177 | 2003 |
| Amyloid fibril formation by pulmonary surfactant protein C M Gustafsson, J Thyberg, J Näslund, E Eliasson, J Johansson FEBS letters 464 (3), 138-142, 1999 | 147 | 1999 |
| Clinical and neuropathological features of the arctic APP gene mutation causing early-onset Alzheimer disease H Basun, N Bogdanovic, M Ingelsson, O Almkvist, J Näslund, K Axelman, ... Archives of neurology 65 (4), 499-505, 2008 | 133 | 2008 |
| The Alzheimer A beta peptide develops protease resistance in association with its polymerization into fibrils. C Nordstedt, J Näslund, LO Tjernberg, AR Karlström, J Thyberg, ... Journal of Biological Chemistry 269 (49), 30773-30776, 1994 | 132 | 1994 |
| Controlling polymerization of β-amyloid and prion-derived peptides with synthetic small molecule ligands P Kuner, B Bohrmann, LO Tjernberg, J Näslund, G Huber, S Celenk, ... Journal of Biological Chemistry 275 (3), 1673-1678, 2000 | 114 | 2000 |
| Pen-2 is sequestered in the endoplasmic reticulum and subjected to ubiquitylation and proteasome-mediated degradation in the absence of presenilin A Bergman, EM Hansson, SE Pursglove, MR Farmery, L Lannfelt, ... Journal of Biological Chemistry 279 (16), 16744-16753, 2004 | 112 | 2004 |
| A sensitive and quantitative assay for measuring cleavage of presenilin substrates H Karlström, A Bergman, U Lendahl, J Näslund, J Lundkvist Journal of Biological Chemistry 277 (9), 6763-6766, 2002 | 111 | 2002 |
| Treatment of alzheimer's disease L Lannfelt, C Nilsberth, A Westlind-Danielsson, J Näslund US Patent 7,179,463, 2007 | 110 | 2007 |
| Quantification of Alzheimer Amyloid β Peptides Ending at Residues 40 and 42 by Novel ELISA Systems M Jensen, T Hartmann, B Engvall, R Wang, SN Uljon, K Sennvik, ... Molecular Medicine 6, 291-302, 2000 | 100 | 2000 |
| γ-Secretase: a complex target for Alzheimer's disease J Lundkvist, J Näslund Current Opinion in Pharmacology 7 (1), 112-118, 2007 | 82 | 2007 |
Samuel GandyIcahn School of Medicine at Mount SinaiПідтверджена електронна адреса в mssm.edu
