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Jan Ludwiczak
Jan Ludwiczak
Prescient Design, Genentech, Roche
Verified email at roche.com
Title
Cited by
Cited by
Year
DeepCoil—a fast and accurate prediction of coiled-coil domains in protein sequences
J Ludwiczak, A Winski, K Szczepaniak, V Alva, S Dunin-Horkawicz
Bioinformatics 35 (16), 2790-2795, 2019
1432019
Rossmann-toolbox: a deep learning-based protocol for the prediction and design of cofactor specificity in Rossmann fold proteins
K Kamiński, J Ludwiczak, M Jasiński, A Bukala, R Madaj, K Szczepaniak, ...
Briefings in Bioinformatics 23 (1), bbab371, 2022
302022
Combining Rosetta with molecular dynamics (MD): a benchmark of the MD-based ensemble protein design
J Ludwiczak, A Jarmula, S Dunin-Horkawicz
Journal of Structural Biology 203 (1), 54-61, 2018
232018
A library of coiled-coil domains: from regular bundles to peculiar twists
K Szczepaniak, A Bukala, AM da Silva Neto, J Ludwiczak, ...
Bioinformatics 36 (22-23), 5368-5376, 2020
192020
Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N 4-hydroxy-dCMP
J Ludwiczak, P Maj, P Wilk, T Frączyk, T Ruman, B Kierdaszuk, A Jarmuła, ...
Molecular BioSystems 12 (4), 1333-1341, 2016
172016
PiPred–a deep-learning method for prediction of π-helices in protein sequences
J Ludwiczak, A Winski, AM da Silva Neto, K Szczepaniak, V Alva, ...
Scientific Reports 9 (1), 6888, 2019
162019
AbDiffuser: full-atom generation of in-vitro functioning antibodies
K Martinkus, J Ludwiczak, WEIC LIANG, J Lafrance-Vanasse, I Hotzel, ...
Advances in Neural Information Processing Systems 36, 2024
142024
pLM-BLAST: distant homology detection based on direct comparison of sequence representations from protein language models
K Kaminski, J Ludwiczak, K Pawlicki, V Alva, S Dunin-Horkawicz
Bioinformatics 39 (10), btad579, 2023
142023
Interplay between DsbA1, DsbA2 and C8J_1298 periplasmic oxidoreductases of Campylobacter jejuni and their impact on bacterial physiology and pathogenesis
AM Banaś, KM Bocian-Ostrzycka, S Dunin-Horkawicz, J Ludwiczak, ...
International Journal of Molecular Sciences 22 (24), 13451, 2021
72021
C8J_1298, a bifunctional thiol oxidoreductase of Campylobacter jejuni, affects Dsb (disulfide bond) network functioning
AM Banaś, KM Bocian-Ostrzycka, M Plichta, S Dunin-Horkawicz, ...
Plos one 15 (3), e0230366, 2020
72020
Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics …
A Jarmuła, P Wilk, P Maj, J Ludwiczak, A Dowierciał, K Banaszak, ...
Journal of Molecular Graphics and Modelling 77, 33-50, 2017
72017
Siah-1-interacting protein regulates mutated huntingtin protein aggregation in Huntington’s disease models
E Latoszek, M Wiweger, J Ludwiczak, S Dunin-Horkawicz, J Kuznicki, ...
Cell & Bioscience 12 (1), 34, 2022
62022
Variability of the core geometry in parallel coiled-coil bundles
K Szczepaniak, J Ludwiczak, A Winski, S Dunin-Horkawicz
Journal of Structural Biology 204 (1), 117-124, 2018
62018
β‐sheet breakers with consecutive phenylalanines: Insights into mechanism of dissolution of β‐amyloid fibrils
A Jarmuła, J Ludwiczak, D Stępkowski
Proteins: Structure, Function, and Bioinformatics 89 (7), 762-780, 2021
42021
Self-analysis of repeat proteins reveals evolutionarily conserved patterns
M Merski, K Młynarczyk, J Ludwiczak, J Skrzeczkowski, ...
Bmc Bioinformatics 21, 1-17, 2020
42020
AlphaFold2 captures the conformational landscape of the HAMP signaling domain
A Winski, J Ludwiczak, M Orlowska, R Madaj, K Kaminski, ...
Protein Science 33 (1), e4846, 2024
32024
localpdb—a Python package to manage protein structures and their annotations
J Ludwiczak, A Winski, S Dunin-Horkawicz
Bioinformatics 38 (9), 2633-2635, 2022
32022
Revealing biophysical properties of KfrA-type proteins as a novel class of cytoskeletal, coiled-coil plasmid-encoded proteins
M Adamczyk, E Lewicka, R Szatkowska, H Nieznanska, J Ludwiczak, ...
BMC microbiology 21, 1-16, 2021
22021
Applicability of AlphaFold2 in the modelling of coiled-coil domains
R Madaj, M Martinez-Goikoetxea, K Kaminski, J Ludwiczak, ...
bioRxiv, 2024.03. 07.583852, 2024
2024
TREM2 Gene Compound Heterozygosity in Neurodegenerative Disorders
M Berdyński, J Ludwiczak, A Barczak, M Barcikowska-Kotowicz, ...
Journal of Alzheimer's Disease 89 (4), 1211-1219, 2022
2022
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