| Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia Cancer Genome Atlas Research Network New England Journal of Medicine 368 (22), 2059-2074, 2013 | 4625 | 2013 |
| The origin and evolution of mutations in acute myeloid leukemia JS Welch, TJ Ley, DC Link, CA Miller, DE Larson, DC Koboldt, ... Cell 150 (2), 264-278, 2012 | 1824 | 2012 |
| Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein K Kondo, J Klco, E Nakamura, M Lechpammer, WG Kaelin Cancer cell 1 (3), 237-246, 2002 | 917 | 2002 |
| Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia TN Wong, G Ramsingh, AL Young, CA Miller, W Touma, JS Welch, ... Nature 518 (7540), 552-555, 2015 | 818 | 2015 |
| Suppression of tumor growth through disruption of hypoxia-inducible transcription AL Kung, S Wang, JM Klco, WG Kaelin, DM Livingston Nature medicine 6 (12), 1335-1340, 2000 | 690 | 2000 |
| von Hippel-Lindau protein mutants linked to type 2C VHL disease preserve the ability to downregulate HIF MA Hoffman, M Ohh, H Yang, JM Klco, M Ivan, WG Kaelin Jr Human molecular genetics 10 (10), 1019-1027, 2001 | 456 | 2001 |
| Functional heterogeneity of genetically defined subclones in acute myeloid leukemia JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ... Cancer cell 25 (3), 379-392, 2014 | 431 | 2014 |
| Immune escape of relapsed AML cells after allogeneic transplantation MJ Christopher, AA Petti, MP Rettig, CA Miller, E Chendamarai, ... New England Journal of Medicine 379 (24), 2330-2341, 2018 | 384 | 2018 |
| Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ... Jama 314 (8), 811-822, 2015 | 379 | 2015 |
| Use of whole-genome sequencing to diagnose a cryptic fusion oncogene JS Welch, P Westervelt, L Ding, DE Larson, JM Klco, S Kulkarni, J Wallis, ... Jama 305 (15), 1577-1584, 2011 | 296 | 2011 |
| Inhibition of vascular endothelial growth factor with a sequence-specific hypoxia response element antagonist BZ Olenyuk, GJ Zhang, JM Klco, NG Nickols, WG Kaelin Jr, PB Dervan Proceedings of the National Academy of Sciences 101 (48), 16768-16773, 2004 | 286 | 2004 |
| The genomic landscape of core-binding factor acute myeloid leukemias ZJ Faber, X Chen, AL Gedman, K Boggs, J Cheng, J Ma, I Radtke, ... Nature genetics 48 (12), 1551-1556, 2016 | 259 | 2016 |
| pVHL modification by NEDD8 is required for fibronectin matrix assembly and suppression of tumor development NH Stickle, J Chung, JM Klco, RP Hill, WG Kaelin Jr, M Ohh Molecular and cellular biology 24 (8), 3251-3261, 2004 | 235 | 2004 |
| Optimizing cancer genome sequencing and analysis M Griffith, CA Miller, OL Griffith, K Krysiak, ZL Skidmore, A Ramu, ... Cell systems 1 (3), 210-223, 2015 | 218 | 2015 |
| Essential role for the second extracellular loop in C5a receptor activation JM Klco, CB Wiegand, K Narzinski, TJ Baranski Nature structural & molecular biology 12 (4), 320-326, 2005 | 192 | 2005 |
| TAK1 restricts spontaneous NLRP3 activation and cell death to control myeloid proliferation RKS Malireddi, P Gurung, J Mavuluri, TK Dasari, JM Klco, H Chi, ... Journal of Experimental Medicine 215 (4), 1023-1034, 2018 | 187 | 2018 |
| The genomic landscape of pediatric myelodysplastic syndromes JR Schwartz, J Ma, T Lamprecht, M Walsh, S Wang, V Bryant, G Song, ... Nature communications 8 (1), 1557, 2017 | 183 | 2017 |
| Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome M Rusch, J Nakitandwe, S Shurtleff, S Newman, Z Zhang, MN Edmonson, ... Nature communications 9 (1), 3962, 2018 | 169 | 2018 |
| Genomic impact of transient low-dose decitabine treatment on primary AML cells JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ... Blood, The Journal of the American Society of Hematology 121 (9), 1633-1643, 2013 | 168 | 2013 |
| Gene expression profiling in a renal cell carcinoma cell line: dissecting VHL and hypoxia-dependent pathways Y Jiang, W Zhang, K Kondo, JM Klco, TB St. Martin, MR Dufault, ... Molecular Cancer Research 1 (6), 453-462, 2003 | 162 | 2003 |
