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Stephen T Buckley
Stephen T Buckley
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Transcellular stomach absorption of a derivatized glucagon-like peptide-1 receptor agonist
ST Buckley, TA Bækdal, A Vegge, SJ Maarbjerg, C Pyke, J Ahnfelt-Rønne, ...
Science translational medicine 10 (467), eaar7047, 2018
3862018
An ingestible self-orienting system for oral delivery of macromolecules
A Abramson, E Caffarel-Salvador, M Khang, D Dellal, D Silverstein, Y Gao, ...
Science 363 (6427), 611-615, 2019
3432019
Semaglutide lowers body weight in rodents via distributed neural pathways
S Gabery, CG Salinas, SJ Paulsen, J Ahnfelt-Rønne, T Alanentalo, ...
JCI insight 5 (6), 2020
2992020
The receptor for advanced glycation end products (RAGE) and the lung
ST Buckley, C Ehrhardt
BioMed Research International 2010, 2010
2892010
Biopharmaceutical classification of poorly soluble drugs with respect to “enabling formulations”
ST Buckley, KJ Frank, G Fricker, M Brandl
European journal of pharmaceutical sciences 50 (1), 8-16, 2013
2112013
In vitro models to evaluate the permeability of poorly soluble drug entities: challenges and perspectives
ST Buckley, SM Fischer, G Fricker, M Brandl
European journal of pharmaceutical sciences 45 (3), 235-250, 2012
1542012
The role of citric acid in oral peptide and protein formulations: relationship between calcium chelation and proteolysis inhibition
SH Welling, F Hubálek, J Jacobsen, DJ Brayden, UL Rahbek, ST Buckley
European journal of pharmaceutics and biopharmaceutics 86 (3), 544-551, 2014
772014
Elucidating the mechanism of absorption of fast-acting insulin aspart: the role of niacinamide
J Kildegaard, ST Buckley, RH Nielsen, GK Povlsen, T Seested, U Ribel, ...
Pharmaceutical research 36, 1-14, 2019
752019
Oral delivery of systemic monoclonal antibodies, peptides and small molecules using gastric auto-injectors
A Abramson, MR Frederiksen, A Vegge, B Jensen, M Poulsen, ...
Nature biotechnology 40 (1), 103-109, 2022
732022
Ligand‐independent transforming growth factor‐β type I receptor signalling mediates type I collagen‐induced epithelial–mesenchymal transition
L DeMaio, ST Buckley, MS Krishnaveni, P Flodby, M Dubourd, A Banfalvi, ...
The Journal of pathology 226 (4), 633-644, 2012
662012
Transport of the fluorescent organic cation 4-(4-(dimethylamino) styryl)-N-methylpyridinium iodide (ASP+) in human respiratory epithelial cells
JJ Salomon, S Endter, G Tachon, F Falson, ST Buckley, C Ehrhardt
European journal of pharmaceutics and biopharmaceutics 81 (2), 351-359, 2012
572012
Interplay between RAGE, CD44, and focal adhesion molecules in epithelial-mesenchymal transition of alveolar epithelial cells
ST Buckley, C Medina, M Kasper, C Ehrhardt
American Journal of Physiology-Lung Cellular and Molecular Physiology 300 (4 …, 2011
572011
Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor …
ST Buckley, C Medina, C Ehrhardt
Cell and tissue research 342 (1), 39-51, 2010
542010
Cytoskeletal re-arrangement in TGF-β1-induced alveolar epithelial-mesenchymal transition studied by atomic force microscopy and high-content analysis
ST Buckley, C Medina, AM Davies, C Ehrhardt
Nanomedicine: Nanotechnology, Biology and Medicine 8 (3), 355-364, 2012
492012
Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism
B Zhou, ST Buckley, V Patel, Y Liu, J Luo, MS Krishnaveni, M Ivan, ...
PloS one 7 (6), e38827, 2012
482012
The insulin receptor is expressed and functional in cultured blood-brain barrier endothelial cells but does not mediate insulin entry from blood to brain
M Hersom, HC Helms, C Schmalz, TÅ Pedersen, ST Buckley, B Brodin
American Journal of Physiology-Endocrinology and Metabolism 315 (4), E531-E542, 2018
462018
Chemically modified peptides and proteins-critical considerations for oral delivery
ST Buckley, F Hubálek, UL Rahbek
Tissue barriers 4 (2), e1156805, 2016
432016
Interaction with mixed micelles in the intestine attenuates the permeation enhancing potential of alkyl-maltosides
K Gradauer, A Nishiumi, K Unrinin, H Higashino, M Kataoka, BL Pedersen, ...
Molecular pharmaceutics 12 (7), 2245-2253, 2015
392015
Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain—a Game Changing Parameter for CNS Drug Discovery and Development
I Loryan, A Reichel, B Feng, C Bundgaard, C Shaffer, C Kalvass, ...
Pharmaceutical research 39 (7), 1321-1341, 2022
382022
In silico modelling of permeation enhancement potency in Caco-2 monolayers based on molecular descriptors and random forest
SH Welling, LKH Clemmensen, ST Buckley, L Hovgaard, PB Brockhoff, ...
European Journal of Pharmaceutics and Biopharmaceutics 94, 152-159, 2015
262015
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