| Causal mechanistic regulatory network for glioblastoma deciphered using systems genetics network analysis CL Plaisier, S O’Brien, B Bernard, S Reynolds, Z Simon, CM Toledo, ... Cell systems 3 (2), 172-186, 2016 | 105 | 2016 |
| Recurring genomic structural variation leads to clonal instability and loss of productivity AA Bandyopadhyay, SA O’Brien, L Zhao, HY Fu, N Vishwanathan, WS Hu Biotechnology and bioengineering 116 (1), 41-53, 2019 | 45 | 2019 |
| Single copy transgene integration in a transcriptionally active site for recombinant protein synthesis SA O'Brien, K Lee, HY Fu, Z Lee, TS Le, CS Stach, MG McCann, ... Biotechnology journal 13 (10), 1800226, 2018 | 39 | 2018 |
| Antagonistic donor density effect conserved in multiple enterococcal conjugative plasmids A Bandyopadhyay, S O'Brien, KL Frank, GM Dunny, WS Hu Applied and environmental microbiology 82 (15), 4537-4545, 2016 | 24 | 2016 |
| Stochasticity in the enterococcal sex pheromone response revealed by quantitative analysis of transcription in single cells RJ Breuer, A Bandyopadhyay, SA O’Brien, AMT Barnes, RC Hunter, ... PLoS genetics 13 (7), e1006878, 2017 | 19 | 2017 |
| Cell culture bioprocessing—the road taken and the path forward SA O’Brien, WS Hu Current opinion in chemical engineering 30, 128-134, 2020 | 8 | 2020 |
| Single-cell analysis reveals that the enterococcal sex pheromone response results in expression of full-length conjugation operon transcripts in all induced cells RJB Erickson, AA Bandyopadhyay, AMT Barnes, SA O’Brien, WS Hu, ... Journal of bacteriology 202 (8), 10.1128/jb. 00685-19, 2020 | 8 | 2020 |
| Multiplexed clonality verification of cell lines for protein biologic production SA O'Brien, J Ojha, P Wu, WS Hu Biotechnology progress 36 (4), e2978, 2020 | 6 | 2020 |
| Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis. Cell Syst 3: 172–186 CL Plaisier, S O’Brien, B Bernard, S Reynolds, Z Simon, CM Toledo, ... | 5 | 2016 |
| Cell Culture bioprocess technology: biologics and beyond S O’Brien, Y Park, S Azarin, WS Hu Cell Culture Technology, 1-21, 2018 | 3 | 2018 |
| Bioreactor scale induced alteration in cell metabolic state can impact amino acid misincorporations in recombinant proteins produced in CHO cells S Boddapati, K Boone, S O’Brien, H Clarke, A Chen, JV Douglass, ... | | 2023 |
| Omics-based characterization of random transgene integration sites from CHO production cell lines S O'Brien, N Patel, J Grantham, H Clarke, J Leinas | | 2023 |
| Cell culture bioprocessing-the road taken and the path forward (vol 30, pg 128, 2020) SA O'Brien, WS Hu CURRENT OPINION IN CHEMICAL ENGINEERING 34, 2021 | | 2021 |
| Genomic analysis and engineering of Chinese Hamster Ovary cells for improved therapeutic protein production SA O'Brien University of Minnesota, 2020 | | 2020 |
| SAM Filtering Pipeline (SFP): Algorithm for the determination of integration sites from next generation sequencing data SA O'Brien, WS Hu | | 2019 |
| Assessment of the genomic instability of CHO cells for cell line development S O'Brien, A Bandyopadhyay, C O'Brien, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 255, 2018 | | 2018 |
| Integrated analysis of genomic and epigenomic instability for CHO cell line engineering S O'Brien, A Bandyopadhyay, C O’Brien, Z Lee, WS Hu | | 2018 |
| A synthetic biology based cell line engineering pipeline WS Hu, CS Stach, S O’Brien, A Bandyopadhyay, M McCann, C O’Brien, ... | | 2018 |
| Use of Site Specific Recombinases to Engineer New Cell Lines for Therapeutic Protein Biomanufacturing SA O'Brien, C Stach, K Lee, MG McCann, N Somia, M Smanski, WS Hu 2017 AIChE Annual Meeting, 2017 | | 2017 |
| Assessing stability, chromatin accessibility and transcriptional activity of the Chinese hamster ovary cell genome A Bandyoapdhyay, Z Lee, C O'Brien, M McCann, S O'Brien, WS Hu ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |
