Yousef Al-abed
Yousef Al-abed
The Feinstein Institute
Підтверджена електронна адреса в
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation
H Wang, M Yu, M Ochani, CA Amella, M Tanovic, S Susarla, JH Li, ...
Nature 421 (6921), 384-388, 2003
Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis
H Wang, H Liao, M Ochani, M Justiniani, X Lin, L Yang, Y Al-Abed, ...
Nature medicine 10 (11), 1216-1221, 2004
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release
H Yang, HS Hreggvidsdottir, K Palmblad, H Wang, M Ochani, J Li, B Lu, ...
Proceedings of the National Academy of Sciences 107 (26), 11942-11947, 2010
Tobacco smoke is a source of toxic reactive glycation products
C Cerami, H Founds, I Nicholl, T Mitsuhashi, D Giordano, S Vanpatten, ...
Proceedings of the National Academy of Sciences 94 (25), 13915-13920, 1997
Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation
RW Saeed, S Varma, T Peng-Nemeroff, B Sherry, D Balakhaneh, ...
The Journal of experimental medicine 201 (7), 1113-1123, 2005
Redox modification of cysteine residues regulates the cytokine activity of high mobility group box-1 (HMGB1).
H Yang, P Lundbäck, L Ottosson, H Erlandsson-Harris, E Venereau, ...
Molecular medicine 18 (2), 2012
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway
VA Pavlov, WR Parrish, M Rosas-Ballina, M Ochani, M Puerta, K Ochani, ...
Brain, behavior, and immunity 23 (1), 41-45, 2009
Characterization of a human RPD3 ortholog, HDAC3
S Emiliani, W Fischle, C Van Lint, Y Al-Abed, E Verdin
Proceedings of the National Academy of Sciences 95 (6), 2795-2800, 1998
Selective α7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis
VA Pavlov, M Ochani, LH Yang, M Gallowitsch-Puerta, K Ochani, X Lin, ...
Critical care medicine 35 (4), 1139-1144, 2007
The tautomerase active site of macrophage migration inhibitory factor is a potential target for discovery of novel anti-inflammatory agents
JB Lubetsky, A Dios, J Han, B Aljabari, B Ruzsicska, R Mitchell, E Lolis, ...
Journal of Biological Chemistry 277 (28), 24976-24982, 2002
ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis
Y Al-Abed, D Dabideen, B Aljabari, A Valster, D Messmer, M Ochani, ...
Journal of Biological Chemistry 280 (44), 36541-36544, 2005
Resveratrol mitigates lipopolysaccharide‐and Aβ‐mediated microglial inflammation by inhibiting the TLR4/NF‐κB/STAT signaling cascade
H Capiralla, V Vingtdeux, H Zhao, R Sankowski, Y Al‐Abed, P Davies, ...
Journal of neurochemistry 120 (3), 461-472, 2012
Central muscarinic cholinergic regulation of the systemic inflammatory response during endotoxemia
VA Pavlov, M Ochani, M Gallowitsch-Puerta, K Ochani, JM Huston, ...
Proceedings of the National Academy of Sciences 103 (13), 5219-5223, 2006
Modulation of TNF release by choline requires α7 subunit nicotinic acetylcholine receptor-mediated signaling
WR Parrish, M Rosas-Ballina, M Gallowitsch-Puerta, M Ochani, K Ochani, ...
Molecular medicine 14 (9), 567-574, 2008
An inducible gene product for 6-phosphofructo-2-kinase with an AU-rich instability element: role in tumor cell glycolysis and the Warburg effect
J Chesney, R Mitchell, F Benigni, M Bacher, L Spiegel, Y Al-Abed, JH Han, ...
Proceedings of the National Academy of Sciences 96 (6), 3047-3052, 1999
MD-2 is required for disulfide HMGB1–dependent TLR4 signaling
H Yang, H Wang, Z Ju, AA Ragab, P Lundbäck, W Long, SI Valdes-Ferrer, ...
Journal of Experimental Medicine 212 (1), 5-14, 2015
Inhibition of macrophage migration inhibitory factor (MIF) tautomerase and biological activities by acetaminophen metabolites
PD Senter, Y Al-Abed, CN Metz, F Benigni, RA Mitchell, J Chesney, J Han, ...
Proceedings of the National Academy of Sciences 99 (1), 144-149, 2002
The selective α7 agonist GTS-21 attenuates cytokine production in human whole blood and human monocytes activated by ligands for TLR2, TLR3, TLR4, TLR9, and RAGE
M Rosas-Ballina, RS Goldstein, M Gallowitsch-Puerta, L Yang, ...
Molecular Medicine 15 (7), 195-202, 2009
Identification of N2-(1-carboxyethyl) guanine (CEG) as a guanine advanced glycosylation end product
A Papoulis, Y Al-Abed, R Bucala
Biochemistry 34 (2), 648-655, 1995
Biochemical and mutational investigations of the enzymatic activity of macrophage migration inhibitory factor
K Bendrat, Y Al-Abed, DJE Callaway, T Peng, T Calandra, CN Metz, ...
Biochemistry 36 (49), 15356-15362, 1997
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