| Ubiquitin‐mediated proteolysis: biological regulation via destruction A Ciechanover, A Orian, AL Schwartz Bioessays 22 (5), 442-451, 2000 | 1096 | 2000 |
| The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation M Welcker, A Orian, J Jin, JA Grim, JW Harper, RN Eisenman, ... Proceedings of the National Academy of Sciences 101 (24), 9085-9090, 2004 | 1026 | 2004 |
| Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway. I Alkalay, A Yaron, A Hatzubai, A Orian, A Ciechanover, Y Ben-Neriah Proceedings of the National Academy of Sciences 92 (23), 10599-10603, 1995 | 624 | 1995 |
| Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor network A Orian, B Van Steensel, J Delrow, HJ Bussemaker, L Li, T Sawado, ... Genes & development 17 (9), 1101-1114, 2003 | 480 | 2003 |
| Degradation of nuclear oncoproteins by the ubiquitin system in vitro. A CIECHANovER, JA DIGIUsEPPE, B Bercovich, A Orian, JD Richter, ... Proceedings of the National Academy of Sciences 88 (1), 139-143, 1991 | 468 | 1991 |
| Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development SS Grewal, L Li, A Orian, RN Eisenman, BA Edgar Nature cell biology 7 (3), 295-302, 2005 | 457 | 2005 |
| The ubiquitin‐mediated proteolytic pathway: Mode of action and clinical implications A Ciechanover, A Orian, AL Schwartz Journal of cellular biochemistry 77 (S34), 40-51, 2000 | 394 | 2000 |
| A nucleolar isoform of the Fbw7 ubiquitin ligase regulates c-Myc and cell size M Welcker, A Orian, JA Grim, RN Eisenman, BE Clurman Current Biology 14 (20), 1852-1857, 2004 | 368 | 2004 |
| Histone deacetylase 6 binds polyubiquitin through its zinc finger (PAZ domain) and copurifies with deubiquitinating enzymes SS Hook, A Orian, SM Cowley, RN Eisenman Proceedings of the National Academy of Sciences 99 (21), 13425-13430, 2002 | 283 | 2002 |
| SCFβ‐TrCP ubiquitin ligase‐mediated processing of NF‐κB p 105 requires phosphorylation of its C‐terminus by IκB kinase A Orian, H Gonen, B Bercovich, I Fajerman, E Eytan, A Israël, F Mercurio, ... The EMBO journal, 2000 | 240 | 2000 |
| Degradation of the proto-oncogene product c-Fos by the ubiquitin proteolytic system in vivo and in vitro: identification and characterization of the conjugating enzymes I Stancovski, H Gonen, A Orian, AL Schwartz, A Ciechanover Molecular and cellular biology, 1995 | 208 | 1995 |
| Ubiquitin-mediated Processing of NF-κB Transcriptional Activator Precursor p105: RECONSTITUTION OF A CELL-FREE SYSTEM AND IDENTIFICATION OF THE UBIQUITIN-CARRIER PROTEIN, E2 … A Orian, S Whiteside, A Israël, I Stancovski, AL Schwartz, A Ciechanover Journal of Biological Chemistry 270 (37), 21707-21714, 1995 | 198 | 1995 |
| Structural motifs involved in ubiquitin-mediated processing of the NF-κB precursor p105: roles of the glycine-rich region and a downstream ubiquitination domain A Orian, AL Schwartz, A Israël, S Whiteside, C Kahana, A Ciechanover Molecular and cellular biology 19 (5), 3664-3673, 1999 | 159 | 1999 |
| Identification of the ubiquitin carrier proteins, E2s, involved in signal-induced conjugation and subsequent degradation of IκBα H Gonen, B Bercovich, A Orian, A Carrano, C Takizawa, K Yamanaka, ... Journal of biological chemistry 274 (21), 14823-14830, 1999 | 148 | 1999 |
| Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice Y Li, R Tinoco, L Elmén, I Segota, Y Xian, Y Fujita, A Sahu, R Zarecki, ... Nature communications 10 (1), 1492, 2019 | 138 | 2019 |
| Hairy Transcriptional Repression Targets and Cofactor Recruitment in Drosophila D Bianchi-Frias, A Orian, JJ Delrow, J Vazquez, AE Rosales-Nieves, ... PLoS biology 2 (7), e178, 2004 | 118 | 2004 |
| Mechanisms of ubiquitin-mediated, limited processingof the NF-κB1 precursor protein p105 A Ciechanover, H Gonen, B Bercovich, S Cohen, I Fajerman, A Israël, ... Biochimie 83 (3-4), 341-349, 2001 | 98 | 2001 |
| Degringolade, a SUMO‐targeted ubiquitin ligase, inhibits Hairy/Groucho‐mediated repression M Abed, KC Barry, D Kenyagin, B Koltun, TM Phippen, JJ Delrow, ... The EMBO journal 30 (7), 1289-1301, 2011 | 73 | 2011 |
| A Myc–Groucho complex integrates EGF and Notch signaling to regulate neural development A Orian, JJ Delrow, AE Rosales Nieves, M Abed, D Metzger, Z Paroush, ... Proceedings of the National Academy of Sciences 104 (40), 15771-15776, 2007 | 66 | 2007 |
| RNF4-dependent oncogene activation by protein stabilization JJ Thomas, M Abed, J Heuberger, R Novak, Y Zohar, APB Lopez, ... Cell reports 16 (12), 3388-3400, 2016 | 61 | 2016 |
