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Katie Ryan
Katie Ryan
Brigham and Women's Hospital/Harvard Medical School
Підтверджена електронна адреса в partners.org
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A transcriptomic atlas of aged human microglia
M Olah, E Patrick, AC Villani, J Xu, CC White, KJ Ryan, P Piehowski, ...
Nature communications 9 (1), 539, 2018
3982018
CD33 modulates TREM2: convergence of Alzheimer loci
G Chan, CC White, PA Winn, M Cimpean, JM Replogle, LR Glick, ...
Nature neuroscience 18 (11), 1556-1558, 2015
1592015
CD33: increased inclusion of exon 2 implicates the Ig V-set domain in Alzheimer's disease susceptibility
T Raj, KJ Ryan, JM Replogle, LB Chibnik, L Rosenkrantz, A Tang, ...
Human molecular genetics 23 (10), 2729-2736, 2014
1552014
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants
KJ Ryan, CC White, K Patel, J Xu, M Olah, JM Replogle, M Frangieh, ...
Science translational medicine 9 (421), eaai7635, 2017
1212017
Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex
EN McNamee, ÉW Griffin, KM Ryan, KJ Ryan, S Heffernan, A Harkin, ...
Neuropharmacology 59 (1-2), 37-48, 2010
812010
The β2-adrenoceptor agonist clenbuterol elicits neuroprotective, anti-inflammatory and neurotrophic actions in the kainic acid model of excitotoxicity
LC Gleeson, KJ Ryan, ÉW Griffin, TJ Connor, A Harkin
Brain, behavior, and immunity 24 (8), 1354-1361, 2010
722010
Noradrenaline acting at central β-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration
EN McNamee, KM Ryan, ÉW Griffin, RE González-Reyes, KJ Ryan, ...
Brain, Behavior, and Immunity 24 (4), 660-671, 2010
702010
Trans-pQTL study identifies immune crosstalk between Parkinson and Alzheimer loci
G Chan, CC White, PA Winn, M Cimpean, JM Replogle, LR Glick, ...
Neurology: Genetics 2 (4), e90, 2016
342016
Effect of body tilt angle on fatigue and EMG activities in lower limbs during cycling
M Egaña, K Ryan, SA Warmington, S Green
European journal of applied physiology 108, 649-656, 2010
322010
Stimulation of central β2-adrenoceptors suppresses NFκB activity in rat brain: a role for IκB
KJ Ryan, É Griffin, JD Yssel, KM Ryan, EN McNamee, A Harkin, ...
Neurochemistry international 63 (5), 368-378, 2013
272013
Spatial orienting of attention to social cues is modulated by cue type and gender of viewer
SM Cooney, N Brady, K Ryan
Experimental brain research 235 (5), 1481-1490, 2017
242017
A transcriptomic atlas of aged human microglia. Nat Commun 9: 539
M Olah, E Patrick, AC Villani, J Xu, CC White, KJ Ryan, P Piehowski, ...
182018
The β2-adrenoceptor agonist clenbuterol reduces the neuroinflammatory response, neutrophil infiltration and apoptosis following intra-striatal IL-1β administration …
ÉW Griffin, JD Yssel, E O’Neill, KJ Ryan, N Boyle, P Harper, A Harkin, ...
Immunopharmacology and immunotoxicology 40 (2), 99-106, 2018
152018
Complementary anti-inflammatory actions of the β2-adrenoceptor agonist clenbuterol and the glucocorticoid dexamethasone in rat brain
KJ Ryan, ÉW Griffin, TJ Connor
Journal of neuroimmunology 232 (1-2), 209-216, 2011
152011
Clenbuterol activates the central IL-1 system via the β2-adrenoceptor without provoking inflammatory response related behaviours in rats
KM Ryan, ÉW Griffin, KJ Ryan, R Tanveer, N Vanattou-Saifoudine, ...
Brain, behavior, and immunity 56, 114-129, 2016
92016
A human microglia-like cellular model for assessing the effects of neurodegenerative disease gene variants. Sci Transl Med 9: eaai7635
KJ Ryan, CC White, K Patel, J Xu, M Olah, JM Replogle, M Frangieh, ...
82017
Context-specific effects of neurodegenerative disease variants in a model of human microglia
KJ Ryan, CC White, K Patel, J Xu, M Olah, JM Replogle, M Frangieh, ...
Science translational medicine 9 (421), 2017
42017
Predictors of slowed non-culprit blood flow post thrombolysis
C McLean, M Rizzo, K Ryan, C McCabe, C Cannon, M Gibson
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 29 (2), 9463-9463, 1997
41997
GW5074 increases microglial phagocytic activities: potential therapeutic direction for Alzheimer’s disease
SM Connor, M Rashid, KJ Ryan, K Patel, JD Boyd, J Smith, W Elyaman, ...
Frontiers in Cellular Neuroscience 16, 894601, 2022
32022
Correcting the functional consequences of the CD33 Alzheimer's disease risk allele using small molecules
JD Boyd
32014
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