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Christopher Hone
Christopher Hone
Principal Scientist, Research Center Pharmaceutical Engineering GbmH
Подтвержден адрес электронной почты в домене honeonline.net
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Процитировано
Процитировано
Год
The use of molecular oxygen for liquid phase aerobic oxidations in continuous flow
CA Hone, CO Kappe
Accounts on Sustainable Flow Chemistry, 67-110, 2020
1562020
The use of molecular oxygen in pharmaceutical manufacturing: is flow the way to go?
CA Hone, DM Roberge, CO Kappe
ChemSusChem 10 (1), 32-41, 2017
1182017
Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions
P Sagmeister, JD Williams, CA Hone, CO Kappe
Reaction Chemistry & Engineering 4 (9), 1571-1578, 2019
982019
Rapid multistep kinetic model generation from transient flow data
CA Hone, N Holmes, GR Akien, RA Bourne, FL Muller
Reaction chemistry & engineering 2 (2), 103-108, 2017
932017
Towards the standardization of flow chemistry protocols for organic reactions
CA Hone, CO Kappe
Chemistry‐Methods 1 (11), 454-467, 2021
732021
Continuous Flow Synthesis of Carbonylated Heterocycles via Pd-Catalyzed Oxidative Carbonylation Using CO and O2 at Elevated Temperatures and Pressures
Y Chen, CA Hone, B Gutmann, CO Kappe
Organic Process Research & Development 21 (7), 1080-1087, 2017
402017
Scalable continuous flow process for the synthesis of eflornithine using fluoroform as difluoromethyl source
M Köckinger, CA Hone, B Gutmann, P Hanselmann, M Bersier, ...
Organic Process Research & Development 22 (11), 1553-1563, 2018
382018
Optimization and scale-up of the continuous flow acetylation and nitration of 4-Fluoro-2-methoxyaniline to prepare a key building block of Osimertinib
M Köckinger, B Wyler, C Aellig, DM Roberge, CA Hone, CO Kappe
Organic Process Research & Development 24 (10), 2217-2227, 2020
292020
Development of a continuous-flow sonogashira cross-coupling protocol using propyne gas under process intensified conditions
D Znidar, CA Hone, P Inglesby, A Boyd, CO Kappe
Organic Process Research & Development 21 (6), 878-884, 2017
272017
HCN on tap: on-demand continuous production of anhydrous HCN for organic synthesis
M Köckinger, CA Hone, CO Kappe
Organic letters 21 (13), 5326-5330, 2019
242019
A Continuous‐Flow Process for Palladium‐Catalyzed Olefin Cleavage by using Oxygen within the Explosive Regime
CA Hone, A O'Kearney‐McMullan, R Munday, CO Kappe
ChemCatChem 9 (17), 3298-3302, 2017
242017
Membrane microreactors for the on‐demand generation, separation, and reaction of gases
CA Hone, CO Kappe
Chemistry–A European Journal 26 (58), 13108-13117, 2020
232020
Definitive screening designs for multistep kinetic models in flow
CA Hone, A Boyd, A O'Kearney-McMullan, RA Bourne, FL Muller
Reaction Chemistry & Engineering 4 (9), 1565-1570, 2019
222019
Optimization and sustainability assessment of a continuous flow Ru-catalyzed ester hydrogenation for an important precursor of a β2-adrenergic receptor agonist
M Prieschl, J García-Lacuna, R Munday, K Leslie, A O'Kearney-McMullan, ...
Green chemistry 22 (17), 5762-5770, 2020
192020
Acyl azide generation and amide bond formation in continuous-flow for the synthesis of peptides
A Mata, U Weigl, O Flögel, P Baur, CA Hone, CO Kappe
Reaction Chemistry & Engineering 5 (4), 645-650, 2020
182020
Continuous‐flow synthesis of aryl aldehydes by Pd‐catalyzed formylation of aryl bromides using carbon monoxide and hydrogen
CA Hone, P Lopatka, R Munday, A O'Kearney‐McMullan, CO Kappe
ChemSusChem 12 (1), 326-337, 2019
182019
Process intensification of ozonolysis reactions using dedicated microstructured reactors
D Polterauer, DM Roberge, P Hanselmann, P Elsner, CA Hone, ...
Reaction Chemistry & Engineering 6 (12), 2253-2258, 2021
162021
Cu-catalyzed aerobic oxidation of diphenyl sulfide to diphenyl sulfoxide within a segmented flow regime: modeling of a consecutive reaction network and reactor characterization
G Vernet, MS Salehi, P Lopatka, SK Wilkinson, SK Bermingham, ...
Chemical Engineering Journal 416, 129045, 2021
152021
The Growing Impact of Continuous Flow Methods on the Twelve Principles of Green Chemistry
AJ Blacker, JR Breen, RA Bourne, CA Hone
152016
Continuous flow synthesis of aryl aldehydes by Pd-catalyzed formylation of phenol-derived aryl fluorosulfonates using syngas
M Köckinger, P Hanselmann, G Hu, CA Hone, CO Kappe
RSC advances 10 (38), 22449-22453, 2020
132020
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