IMP/GTP balance modulates cytoophidium assembly and IMPDH activity GD Keppeke, CC Chang, M Peng, LY Chen, WC Lin, LM Pai, ... Cell division 13, 1-18, 2018 | 67 | 2018 |
CTP synthase forms the cytoophidium in human hepatocellular carcinoma CC Chang, YM Jeng, M Peng, GD Keppeke, LY Sung, JL Liu Experimental Cell Research 361 (2), 292-299, 2017 | 66 | 2017 |
Longitudinal study of a human drug-induced model of autoantibody to cytoplasmic rods/rings following HCV therapy with ribavirin and interferon-α GD Keppeke, E Nunes, MLG Ferraz, EAB Silva, C Granato, EKL Chan, ... Public Library of Science 7 (9), e45392, 2012 | 60 | 2012 |
Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction GD Keppeke, SJ Calise, EKL Chan, LEC Andrade Journal of Genetics and genomics 42 (6), 287-299, 2015 | 58 | 2015 |
Interfilament interaction between IMPDH and CTPS cytoophidia CC Chang, GD Keppeke, LY Sung, JL Liu The FEBS journal 285 (20), 3753-3768, 2018 | 52 | 2018 |
Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-α/ribavirin therapy GD Keppeke, SJ Calise, EKL Chan, LEC Andrade World journal of gastroenterology 22 (6), 1966, 2016 | 43 | 2016 |
Anti-rods/rings: a human model of drug-induced autoantibody generation SJ Calise, GD Keppeke, LEC Andrade, EKL Chan Frontiers in immunology 6, 130386, 2015 | 38 | 2015 |
Temporal evolution of human autoantibody response to cytoplasmic rods and rings structure during anti-HCV therapy with ribavirin and interferon-α GD Keppeke, M Satoh, MLG Ferraz, EKL Chan, LEC Andrade Immunologic research 60, 38-49, 2014 | 29 | 2014 |
Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies GD Keppeke, MS Prado, E Nunes, SF Perazzio, SH Rodrigues, ... Clinical Immunology 173, 149-156, 2016 | 26 | 2016 |
Nasal administration of anti-CD3 monoclonal antibody (Foralumab) reduces lung inflammation and blood inflammatory biomarkers in mild to moderate COVID-19 patients: A pilot study TG Moreira, KTF Matos, GS De Paula, TMM Santana, RG Da Mata, ... Frontiers in Immunology 12, 709861, 2021 | 20 | 2021 |
Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures GD Keppeke, LEC Andrade, SS Grieshaber, EKL Chan Cell & bioscience 5, 1-11, 2015 | 20 | 2015 |
Ribavirin induces widespread accumulation of IMP dehydrogenase into rods/rings structures in multiple major mouse organs GD Keppeke, SJ Calise, EKL Chan, LEC Andrade Antiviral Research 162, 130-135, 2019 | 17 | 2019 |
Psychological characteristics of caregivers of pediatric patients with chronic rheumatic disease in relation to treatment adherence LF Keppeke, J Molina, VB Miotto e Silva, MTSLRA Terreri, GD Keppeke, ... Pediatric Rheumatology 16, 1-11, 2018 | 16 | 2018 |
Molecular crowding facilitates bundling of IMPDH polymers and cytoophidium formation CC Chang, M Peng, J Zhong, Z Zhang, GD Keppeke, LY Sung, JL Liu Cellular and Molecular Life Sciences 79 (8), 420, 2022 | 15 | 2022 |
CTPS forms the cytoophidium in zebrafish CC Chang, GD Keppeke, CL Antos, M Peng, LEC Andrade, LY Sung, ... Experimental Cell Research 405 (2), 112684, 2021 | 13 | 2021 |
IMPDH-based cytoophidium structures as potential theranostics in cancer GD Keppeke, LEC Andrade, D Barcelos, M Fernandes, G Landman Molecular Therapy 28 (7), 1557-1558, 2020 | 9 | 2020 |
IMP dehydrogenase rod/ring structures in acral melanomas GD Keppeke, D Barcelos, M Fernandes, AN Comodo, DP Guimaraes, ... Pigment Cell & Melanoma Research 33 (3), 490-497, 2020 | 9 | 2020 |
A cell-based assay for detection of anti-fibrillarin autoantibodies with performance equivalent to immunoprecipitation GD Keppeke, M Satoh, C Kayser, P Matos, T Hasegawa, S Tanaka, ... Frontiers in Immunology 13, 1011110, 2022 | 8 | 2022 |
IMPDH forms the cytoophidium in zebrafish GD Keppeke, CC Chang, CL Antos, M Peng, LY Sung, LEC Andrade, ... Developmental Biology 478, 89-101, 2021 | 7 | 2021 |
Effect on cell survival and cytoophidium assembly of the adRP-10-related IMPDH1 missense mutation Asp226Asn GD Keppeke, CC Chang, Z Zhang, JL Liu Frontiers in Cell and Developmental Biology 11, 2023 | 5 | 2023 |