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Gerson D Keppeke
Gerson D Keppeke
Підтверджена електронна адреса в unifesp.br - Домашня сторінка
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IMP/GTP balance modulates cytoophidium assembly and IMPDH activity
GD Keppeke, CC Chang, M Peng, LY Chen, WC Lin, LM Pai, ...
Cell division 13, 1-18, 2018
672018
CTP synthase forms the cytoophidium in human hepatocellular carcinoma
CC Chang, YM Jeng, M Peng, GD Keppeke, LY Sung, JL Liu
Experimental Cell Research 361 (2), 292-299, 2017
662017
Longitudinal study of a human drug-induced model of autoantibody to cytoplasmic rods/rings following HCV therapy with ribavirin and interferon-α
GD Keppeke, E Nunes, MLG Ferraz, EAB Silva, C Granato, EKL Chan, ...
Public Library of Science 7 (9), e45392, 2012
602012
Assembly of IMPDH2-based, CTPS-based, and mixed rod/ring structures is dependent on cell type and conditions of induction
GD Keppeke, SJ Calise, EKL Chan, LEC Andrade
Journal of Genetics and genomics 42 (6), 287-299, 2015
582015
Interfilament interaction between IMPDH and CTPS cytoophidia
CC Chang, GD Keppeke, LY Sung, JL Liu
The FEBS journal 285 (20), 3753-3768, 2018
522018
Anti-rods/rings autoantibody generation in hepatitis C patients during interferon-α/ribavirin therapy
GD Keppeke, SJ Calise, EKL Chan, LEC Andrade
World journal of gastroenterology 22 (6), 1966, 2016
432016
Anti-rods/rings: a human model of drug-induced autoantibody generation
SJ Calise, GD Keppeke, LEC Andrade, EKL Chan
Frontiers in immunology 6, 130386, 2015
382015
Temporal evolution of human autoantibody response to cytoplasmic rods and rings structure during anti-HCV therapy with ribavirin and interferon-α
GD Keppeke, M Satoh, MLG Ferraz, EKL Chan, LEC Andrade
Immunologic research 60, 38-49, 2014
292014
Differential capacity of therapeutic drugs to induce Rods/Rings structures in vitro and in vivo and generation of anti-Rods/Rings autoantibodies
GD Keppeke, MS Prado, E Nunes, SF Perazzio, SH Rodrigues, ...
Clinical Immunology 173, 149-156, 2016
262016
Nasal administration of anti-CD3 monoclonal antibody (Foralumab) reduces lung inflammation and blood inflammatory biomarkers in mild to moderate COVID-19 patients: A pilot study
TG Moreira, KTF Matos, GS De Paula, TMM Santana, RG Da Mata, ...
Frontiers in Immunology 12, 709861, 2021
202021
Microinjection of specific anti-IMPDH2 antibodies induces disassembly of cytoplasmic rods/rings that are primarily stationary and stable structures
GD Keppeke, LEC Andrade, SS Grieshaber, EKL Chan
Cell & bioscience 5, 1-11, 2015
202015
Ribavirin induces widespread accumulation of IMP dehydrogenase into rods/rings structures in multiple major mouse organs
GD Keppeke, SJ Calise, EKL Chan, LEC Andrade
Antiviral Research 162, 130-135, 2019
172019
Psychological characteristics of caregivers of pediatric patients with chronic rheumatic disease in relation to treatment adherence
LF Keppeke, J Molina, VB Miotto e Silva, MTSLRA Terreri, GD Keppeke, ...
Pediatric Rheumatology 16, 1-11, 2018
162018
Molecular crowding facilitates bundling of IMPDH polymers and cytoophidium formation
CC Chang, M Peng, J Zhong, Z Zhang, GD Keppeke, LY Sung, JL Liu
Cellular and Molecular Life Sciences 79 (8), 420, 2022
152022
CTPS forms the cytoophidium in zebrafish
CC Chang, GD Keppeke, CL Antos, M Peng, LEC Andrade, LY Sung, ...
Experimental Cell Research 405 (2), 112684, 2021
132021
IMPDH-based cytoophidium structures as potential theranostics in cancer
GD Keppeke, LEC Andrade, D Barcelos, M Fernandes, G Landman
Molecular Therapy 28 (7), 1557-1558, 2020
92020
IMP dehydrogenase rod/ring structures in acral melanomas
GD Keppeke, D Barcelos, M Fernandes, AN Comodo, DP Guimaraes, ...
Pigment Cell & Melanoma Research 33 (3), 490-497, 2020
92020
A cell-based assay for detection of anti-fibrillarin autoantibodies with performance equivalent to immunoprecipitation
GD Keppeke, M Satoh, C Kayser, P Matos, T Hasegawa, S Tanaka, ...
Frontiers in Immunology 13, 1011110, 2022
82022
IMPDH forms the cytoophidium in zebrafish
GD Keppeke, CC Chang, CL Antos, M Peng, LY Sung, LEC Andrade, ...
Developmental Biology 478, 89-101, 2021
72021
Effect on cell survival and cytoophidium assembly of the adRP-10-related IMPDH1 missense mutation Asp226Asn
GD Keppeke, CC Chang, Z Zhang, JL Liu
Frontiers in Cell and Developmental Biology 11, 2023
52023
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