α-Synuclein pathology in Parkinson’s disease and related α-synucleinopathies MX Henderson, JQ Trojanowski, VMY Lee Neuroscience letters 709, 134316, 2019 | 233 | 2019 |
Spread of α-synuclein pathology through the brain connectome is modulated by selective vulnerability and predicted by network analysis MX Henderson, EJ Cornblath, A Darwich, B Zhang, H Brown, ... Nature neuroscience 22 (8), 1248-1257, 2019 | 217 | 2019 |
Alzheimer’s disease tau is a prominent pathology in LRRK2 Parkinson’s disease MX Henderson, M Sengupta, JQ Trojanowski, VMY Lee Acta neuropathologica communications 7, 1-16, 2019 | 112 | 2019 |
Identification of CSPα clients reveals a role in dynamin 1 regulation YQ Zhang, MX Henderson, CM Colangelo, SD Ginsberg, C Bruce, T Wu, ... Neuron 74 (1), 136-150, 2012 | 108 | 2012 |
Glucocerebrosidase activity modulates neuronal susceptibility to pathological α-synuclein insult MX Henderson, S Sedor, I McGeary, EJ Cornblath, C Peng, DM Riddle, ... Neuron 105 (5), 822-836. e7, 2020 | 107 | 2020 |
Neuronal ceroid lipofuscinosis with DNAJC5/CSPα mutation has PPT1 pathology and exhibit aberrant protein palmitoylation MX Henderson, GS Wirak, Y Zhang, F Dai, SD Ginsberg, N Dolzhanskaya, ... Acta neuropathologica 131, 621-637, 2016 | 78 | 2016 |
Glucose sensitivity of mouse olfactory bulb neurons is conveyed by a voltage‐gated potassium channel K Tucker, S Cho, N Thiebaud, MX Henderson, DA Fadool The Journal of physiology 591 (10), 2541-2561, 2013 | 49 | 2013 |
LRRK2 inhibition does not impart protection from α-synuclein pathology and neuron death in non-transgenic mice MX Henderson, M Sengupta, I McGeary, B Zhang, MF Olufemi, H Brown, ... Acta neuropathologica communications 7, 1-12, 2019 | 45 | 2019 |
LRRK2 activity does not dramatically alter α-synuclein pathology in primary neurons MX Henderson, C Peng, JQ Trojanowski, VMY Lee Acta neuropathologica communications 6, 1-11, 2018 | 44 | 2018 |
Unbiased proteomics of early Lewy body formation model implicates active microtubule affinity-regulating kinases (MARKs) in synucleinopathies MX Henderson, CHY Chung, DM Riddle, B Zhang, RJ Gathagan, ... Journal of Neuroscience 37 (24), 5870-5884, 2017 | 38 | 2017 |
Characterization of novel conformation-selective α-synuclein antibodies as potential immunotherapeutic agents for Parkinson's disease MX Henderson, DJ Covell, CHY Chung, RM Pitkin, RM Sandler, ... Neurobiology of disease 136, 104712, 2020 | 34 | 2020 |
Computational modeling of tau pathology spread reveals patterns of regional vulnerability and the impact of a genetic risk factor EJ Cornblath, HL Li, L Changolkar, B Zhang, HJ Brown, RJ Gathagan, ... Science advances 7 (24), eabg6677, 2021 | 29 | 2021 |
The roles of connectivity and neuronal phenotype in determining the pattern of α-synuclein pathology in Parkinson's disease MX Henderson, MT Henrich, FF Geibl, WH Oertel, P Brundin, DJ Surmeier Neurobiology of disease 168, 105687, 2022 | 18 | 2022 |
Synaptic location is a determinant of the detrimental effects of α-synuclein pathology to glutamatergic transmission in the basolateral amygdala L Chen, C Nagaraja, S Daniels, ZA Fisk, R Dvorak, L Meyerdirk, ... Elife 11, e78055, 2022 | 7 | 2022 |
LRRK2 kinase activity does not alter cell-autonomous tau pathology development in primary neurons MX Henderson, L Changolkar, JQ Trojanowski, VMY Lee Journal of Parkinson's Disease 11 (3), 1187-1196, 2021 | 7 | 2021 |
Urinary tract infections trigger synucleinopathy via the innate immune response W Peelaerts, G Mercado, S George, M Villumsen, A Kasen, M Aguileta, ... Acta neuropathologica 145 (5), 541-559, 2023 | 6 | 2023 |
Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson’s disease CEG Leyns, A Prigent, B Beezhold, L Yao, NG Hatcher, P Tao, J Kang, ... npj Parkinson's Disease 9 (1), 74, 2023 | 5 | 2023 |
A novel automated morphological analysis of Iba1+ microglia using a deep learning assisted model L Stetzik, G Mercado, L Smith, S George, E Quansah, K Luda, E Schulz, ... Frontiers in cellular neuroscience 16, 944875, 2022 | 4 | 2022 |
Network models to enhance the translational impact of cross-species studies JK Brynildsen, K Rajan, MX Henderson, DS Bassett Nature Reviews Neuroscience 24 (9), 575-588, 2023 | 3 | 2023 |
A novel automated morphological analysis of microglia activation using a deep learning assisted model S Lucas, M Gabriela, S Lindsey, G Sonia, Q Emmanuel, L Katarzyna, ... bioRxiv, 2022.03. 11.483994, 2022 | 2 | 2022 |