Jurgen R Haanstra
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Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei
MA Albert, JR Haanstra, V Hannaert, J Van Roy, FR Opperdoes, ...
Journal of Biological Chemistry 280 (31), 28306-28315, 2005
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
JR Haanstra, A van Tuijl, P Kessler, W Reijnders, PAM Michels, ...
Proceedings of the National Academy of Sciences 105 (46), 17718-17723, 2008
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia
R Beekman, MG Valkhof, MA Sanders, PMH Van Strien, JR Haanstra, ...
Blood, The Journal of the American Society of Hematology 119 (22), 5071-5077, 2012
Transcriptome‐wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co‐transcriptional degradation in determining mRNA levels
A Fadda, M Ryten, D Droll, F Rojas, V Färber, JR Haanstra, C Merce, ...
Molecular microbiology 94 (2), 307-326, 2014
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites
JR Haanstra, EB González-Marcano, M Gualdrón-López, PAM Michels
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (5), 1038-1048, 2016
EVI1 is critical for the pathogenesis of a subset of MLL-AF9–rearranged AMLs
EMJ Bindels, M Havermans, S Lugthart, C Erpelinck, E Wocjtowicz, ...
Blood, The Journal of the American Society of Hematology 119 (24), 5838-5849, 2012
Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei
JR Haanstra, M Stewart, VD Luu, A van Tuijl, HV Westerhoff, C Clayton, ...
Journal of Biological Chemistry 283 (5), 2495-2507, 2008
Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event
MJH Kas, AW Bruijnzeel, JR Haanstra, VM Wiegant, RAH Adan
Journal of molecular endocrinology 35 (1), 159-164, 2005
Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors
A Wölfler, AA Danen-van Oorschot, JR Haanstra, M Valkhof, C Bodner, ...
Blood, The Journal of the American Society of Hematology 116 (20), 4116-4125, 2010
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism
S Pieretti, JR Haanstra, M Mazet, R Perozzo, C Bergamini, F Prati, R Fato, ...
PLoS neglected tropical diseases 7 (1), e2012, 2013
A domino effect in drug action: from metabolic assault towards parasite differentiation
JR Haanstra, EJ Kerkhoven, A Van Tuijl, M Blits, M Wurst, R Van Nuland, ...
Molecular microbiology 79 (1), 94-108, 2011
Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids
B Szöör, JR Haanstra, M Gualdrón-López, PAM Michels
Current opinion in microbiology 22, 79-87, 2014
Targeting pathogen metabolism without collateral damage to the host
JR Haanstra, A Gerding, AM Dolga, FJ Sorgdrager, M Buist-Homan, ...
Scientific Reports 7, 40406, 2017
Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression
EB Antwi, JR Haanstra, G Ramasamy, B Jensen, D Droll, F Rojas, I Minia, ...
BMC genomics 17 (1), 1-16, 2016
ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation
MF Alemdehy, JR Haanstra, HWJ de Looper, PMH van Strien, ...
Blood, The Journal of the American Society of Hematology 125 (25), 3937-3948, 2015
Network-based selectivity of antiparasitic inhibitors
BM Bakker, HE Assmus, F Bruggeman, JR Haanstra, E Klipp, ...
Molecular biology reports 29 (1-2), 1-5, 2002
Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes
JR Haanstra, A van Tuijl, J van Dam, W van Winden, AGM Tielens, ...
International journal for parasitology 42 (7), 667-673, 2012
Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling
AE Leroux, JR Haanstra, BM Bakker, RL Krauth-Siegel
Journal of Biological Chemistry 288 (33), 23751-23764, 2013
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux
E Bosdriesz, MT Wortel, JR Haanstra, MJ Wagner, P De La Torre Cortés, ...
Scientific reports 8 (1), 1-9, 2018
In or out? On the tightness of glycosomal compartmentalization of metabolites and enzymes in Trypanosoma brucei
JR Haanstra, BM Bakker, PAM Michels
Molecular and biochemical parasitology 198 (1), 18-28, 2014
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