| A presenilin-1/γ-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions P Marambaud, J Shioi, G Serban, A Georgakopoulos, S Sarner, V Nagy, ... The EMBO journal 21 (8), 1948-1956, 2002 | 908 | 2002 |
| Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides. NK Robakis, N Ramakrishna, G Wolfe, HM Wisniewski Proceedings of the National Academy of Sciences 84 (12), 4190-4194, 1987 | 857 | 1987 |
| A CBP binding transcriptional repressor produced by the PS1/ϵ-cleavage of N-cadherin is inhibited by PS1 FAD mutations P Marambaud, PH Wen, A Dutt, J Shioi, A Takashima, R Siman, ... Cell 114 (5), 635-645, 2003 | 597 | 2003 |
| Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide MA Pappolla, M Sos, RA Omar, RJ Bick, DLM Hickson-Bick, RJ Reiter, ... Journal of Neuroscience 17 (5), 1683-1690, 1997 | 517 | 1997 |
| Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease. MA Pappolla, RA Omar, KS Kim, NK Robakis The American journal of pathology 140 (3), 621, 1992 | 508 | 1992 |
| Inhibition of Alzheimer β-fibrillogenesis by melatonin M Pappolla, P Bozner, C Soto, H Shao, NK Robakis, M Zagorski, ... Journal of Biological Chemistry 273 (13), 7185-7188, 1998 | 450 | 1998 |
| Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome NK Robakis, HM Wisniewski, EC Jenkins, EA Devine-Gage, GE Houck, ... The Lancet 329 (8529), 384-385, 1987 | 375 | 1987 |
| Alzheimer's disease: a re-examination of the amyloid hypothesis RL Neve, NK Robakis Trends in neurosciences 21 (1), 15-19, 1998 | 370 | 1998 |
| Amyloid-independent mechanisms in Alzheimer's disease pathogenesis SW Pimplikar, RA Nixon, NK Robakis, J Shen, LH Tsai Journal of Neuroscience 30 (45), 14946-14954, 2010 | 365 | 2010 |
| PS1 activates PI3K thus inhibiting GSK‐3 activity and tau overphosphorylation: effects of FAD mutations L Baki, J Shioi, P Wen, Z Shao, A Schwarzman, M Gama‐Sosa, R Neve, ... The EMBO journal 23 (13), 2586-2596, 2004 | 354 | 2004 |
| Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells JP Anderson, FS Esch, PS Keim, K Sambamurti, I Lieberburg, NK Robakis Neuroscience letters 128 (1), 126-128, 1991 | 323 | 1991 |
| Presenilin-1 forms complexes with the cadherin/catenin cell–cell adhesion system and is recruited to intercellular and synaptic contacts A Georgakopoulos, P Marambaud, S Efthimiopoulos, J Shioi, W Cui, ... Molecular cell 4 (6), 893-902, 1999 | 275 | 1999 |
| A role for noncoding variation in schizophrenia P Roussos, AC Mitchell, G Voloudakis, JF Fullard, VM Pothula, J Tsang, ... Cell reports 9 (4), 1417-1429, 2014 | 268 | 2014 |
| Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex L Baki, P Marambaud, S Efthimiopoulos, A Georgakopoulos, P Wen, ... Proceedings of the National Academy of Sciences 98 (5), 2381-2386, 2001 | 233 | 2001 |
| The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice PH Wen, PR Hof, X Chen, K Gluck, G Austin, SG Younkin, LH Younkin, ... Experimental neurology 188 (2), 224-237, 2004 | 231 | 2004 |
| Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB‐induced Src phosphorylation and signaling A Georgakopoulos, C Litterst, E Ghersi, L Baki, CJ Xu, G Serban, ... The EMBO journal 25 (6), 1242-1252, 2006 | 211 | 2006 |
| Increased expression but reduced activity of antioxidant enzymes in Alzheimer's disease RA Omar, YJ Chyan, AC Andorn, B Poeggeler, NK Robakis, MA Pappolla Journal of Alzheimer's Disease 1 (3), 139-145, 1999 | 200 | 1999 |
| Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells K Sambamurti, J Shioi, JP Anderson, MA Pappolla, NK Robakis Journal of neuroscience research 33 (2), 319-329, 1992 | 189 | 1992 |
| Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains RJ Kascsak, R Rubenstein, PA Merz, RI Carp, NK Robakis, ... Journal of virology 59 (3), 676-683, 1986 | 182 | 1986 |
| Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase. SB Roberts, JA Ripellino, KM Ingalls, NK Robakis, KM Felsenstein Journal of Biological Chemistry 269 (4), 3111-3116, 1994 | 177 | 1994 |
