N Robakis
N Robakis
Підтверджена електронна адреса в mssm.edu
A presenilin‐1/γ‐secretase cleavage releases the E‐cadherin intracellular domain and regulates disassembly of adherens junctions
P Marambaud, J Shioi, G Serban, A Georgakopoulos, S Sarner, V Nagy, ...
The EMBO journal 21 (8), 1948-1956, 2002
Molecular cloning and characterization of a cDNA encoding the cerebrovascular and the neuritic plaque amyloid peptides
NK Robakis, N Ramakrishna, G Wolfe, HM Wisniewski
Proceedings of the National Academy of Sciences 84 (12), 4190-4194, 1987
A CBP binding transcriptional repressor produced by the PS1/ϵ-cleavage of N-cadherin is inhibited by PS1 FAD mutations
P Marambaud, PH Wen, A Dutt, J Shioi, A Takashima, R Siman, ...
Cell 114 (5), 635-645, 2003
Melatonin prevents death of neuroblastoma cells exposed to the Alzheimer amyloid peptide
MA Pappolla, M Sos, RA Omar, RJ Bick, DLM Hickson-Bick, RJ Reiter, ...
Journal of Neuroscience 17 (5), 1683-1690, 1997
Immunohistochemical evidence of oxidative [corrected] stress in Alzheimer's disease.
MA Pappolla, RA Omar, KS Kim, NK Robakis
The American journal of pathology 140 (3), 621, 1992
Inhibition of Alzheimer β-fibrillogenesis by melatonin
M Pappolla, P Bozner, C Soto, H Shao, NK Robakis, M Zagorski, ...
Journal of Biological Chemistry 273 (13), 7185-7188, 1998
Alzheimer's disease: a re-examination of the amyloid hypothesis
RL Neve, NK Robakis
Trends in neurosciences 21 (1), 15-19, 1998
Chromosome 21q21 sublocalisation of gene encoding beta-amyloid peptide in cerebral vessels and neuritic (senile) plaques of people with Alzheimer disease and Down syndrome
NK Robakis, HM Wisniewski, EC Jenkins, EA Devine-Gage, GE Houck, ...
The Lancet 329 (8529), 384-385, 1987
PS1 activates PI3K thus inhibiting GSK‐3 activity and tau overphosphorylation: effects of FAD mutations
L Baki, J Shioi, P Wen, Z Shao, A Schwarzman, M Gama‐Sosa, R Neve, ...
The EMBO journal 23 (13), 2586-2596, 2004
Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells
JP Anderson, FS Esch, PS Keim, K Sambamurti, I Lieberburg, NK Robakis
Neuroscience letters 128 (1), 126-128, 1991
Amyloid-independent mechanisms in Alzheimer's disease pathogenesis
SW Pimplikar, RA Nixon, NK Robakis, J Shen, LH Tsai
Journal of Neuroscience 30 (45), 14946-14954, 2010
Presenilin-1 forms complexes with the cadherin/catenin cell–cell adhesion system and is recruited to intercellular and synaptic contacts
A Georgakopoulos, P Marambaud, S Efthimiopoulos, J Shioi, W Cui, ...
Molecular cell 4 (6), 893-902, 1999
Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex
L Baki, P Marambaud, S Efthimiopoulos, A Georgakopoulos, P Wen, ...
Proceedings of the National Academy of Sciences 98 (5), 2381-2386, 2001
The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice
PH Wen, PR Hof, X Chen, K Gluck, G Austin, SG Younkin, LH Younkin, ...
Experimental neurology 188 (2), 224-237, 2004
A role for noncoding variation in schizophrenia
P Roussos, AC Mitchell, G Voloudakis, JF Fullard, VM Pothula, J Tsang, ...
Cell reports 9 (4), 1417-1429, 2014
Metalloproteinase/Presenilin1 processing of ephrinB regulates EphB‐induced Src phosphorylation and signaling
A Georgakopoulos, C Litterst, E Ghersi, L Baki, CJ Xu, G Serban, ...
The EMBO journal 25 (6), 1242-1252, 2006
Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells
K Sambamurti, J Shioi, JP Anderson, MA Pappolla, NK Robakis
Journal of neuroscience research 33 (2), 319-329, 1992
Immunological comparison of scrapie-associated fibrils isolated from animals infected with four different scrapie strains
RJ Kascsak, R Rubenstein, PA Merz, RI Carp, NK Robakis, ...
Journal of virology 59 (3), 676-683, 1986
Nerve and epidermal growth factors induce the release of the Alzheimer amyloid precursor from PC 12 cell cultures
LM Refolo, SRJ Salton, JP Anderson, P Mehta, NK Robakis
Biochemical and biophysical research communications 164 (2), 664-670, 1989
Non-amyloidogenic cleavage of the beta-amyloid precursor protein by an integral membrane metalloendopeptidase.
SB Roberts, JA Ripellino, KM Ingalls, NK Robakis, KM Felsenstein
Journal of Biological Chemistry 269 (4), 3111-3116, 1994
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