Alexander (Sasha) Gusev
Alexander (Sasha) Gusev
Dana-Farber Cancer Institute
Підтверджена електронна адреса в dfci.harvard.edu - Домашня сторінка
Назва
Посилання
Посилання
Рік
An atlas of genetic correlations across human diseases and traits
B Bulik-Sullivan, HK Finucane, V Anttila, A Gusev, FR Day, PR Loh, ...
Nature genetics 47 (11), 1236, 2015
1603*2015
Partitioning heritability by functional annotation using genome-wide association summary statistics
HK Finucane, B Bulik-Sullivan, A Gusev, G Trynka, Y Reshef, PR Loh, ...
Nature genetics 47 (11), 1228, 2015
9732015
Integrative approaches for large-scale transcriptome-wide association studies
A Gusev, A Ko, H Shi, G Bhatia, W Chung, B Penninx, R Jansen, E Geus, ...
Nature Genetics 48 (3), 245–252, 2016
6492016
Modeling linkage disequilibrium increases accuracy of polygenic risk scores
BJ Vilhjálmsson, J Yang, HK Finucane, A Gusev, S Lindström, S Ripke, ...
The american journal of human genetics 97 (4), 576-592, 2015
5062015
Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
A Gusev, SH Lee, G Trynka, H Finucane, BJ Vilhjálmsson, H Xu, C Zang, ...
The American Journal of Human Genetics 95 (5), 535-552, 2014
4512014
Whole population, genome-wide mapping of hidden relatedness
A Gusev, JK Lowe, M Stoffel, MJ Daly, D Altshuler, JL Breslow, ...
Genome research 19 (2), 318-326, 2009
3942009
Contrasting genetic architectures of schizophrenia and other complex diseases using fast variance-components analysis
PR Loh, G Bhatia, A Gusev, HK Finucane, BK Bulik-Sullivan, SJ Pollack, ...
Nature genetics 47 (12), 1385, 2015
2832015
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types
HK Finucane, YA Reshef, V Anttila, K Slowikowski, A Gusev, A Byrnes, ...
Nature genetics 50 (4), 621-629, 2018
2622018
Linkage disequilibrium–dependent architecture of human complex traits shows action of negative selection
S Gazal, HK Finucane, NA Furlotte, PR Loh, PF Palamara, X Liu, ...
Nature genetics 49 (10), 1421, 2017
1592017
Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
A Gusev, N Mancuso, H Won, M Kousi, HK Finucane, Y Reshef, L Song, ...
Nature genetics 50 (4), 538-548, 2018
1482018
Integrating gene expression with summary association statistics to identify genes associated with 30 complex traits
N Mancuso, H Shi, P Goddard, G Kichaev, A Gusev, B Pasaniuc
The American Journal of Human Genetics 100 (3), 473-487, 2017
1422017
Fast and accurate imputation of summary statistics enhances evidence of functional enrichment
B Pasaniuc, N Zaitlen, H Shi, G Bhatia, A Gusev, J Pickrell, J Hirschhorn, ...
Bioinformatics 30 (20), 2906-2914, 2014
1422014
Quantifying missing heritability at known GWAS loci
A Gusev, G Bhatia, N Zaitlen, BJ Vilhjalmsson, D Diogo, EA Stahl, ...
PLoS Genet 9 (12), e1003993, 2013
1182013
The architecture of long-range haplotypes shared within and across populations
A Gusev, PF Palamara, G Aponte, Z Zhuang, A Darvasi, P Gregersen, ...
Molecular biology and evolution 29 (2), 473-486, 2012
852012
DASH: a method for identical-by-descent haplotype mapping uncovers association with recent variation
A Gusev, EE Kenny, JK Lowe, J Salit, R Saxena, S Kathiresan, ...
American journal of human genetics 88 (6), 706, 2011
612011
A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
L Wu, W Shi, J Long, X Guo, K Michailidou, J Beesley, MK Bolla, XO Shu, ...
Nature genetics 50 (7), 968-978, 2018
602018
Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits
F Hormozdiari, S Gazal, B van de Geijn, HK Finucane, CJT Ju, PR Loh, ...
Nature genetics 50 (7), 1041-1047, 2018
582018
Probabilistic fine-mapping of transcriptome-wide association studies
N Mancuso, MK Freund, R Johnson, H Shi, G Kichaev, A Gusev, ...
Nature genetics 51 (4), 675-682, 2019
552019
Leveraging distant relatedness to quantify human mutation and gene-conversion rates
PF Palamara, LC Francioli, PR Wilton, G Genovese, A Gusev, ...
The American Journal of Human Genetics 97 (6), 775-789, 2015
542015
Leveraging population admixture to characterize the heritability of complex traits
N Zaitlen, B Pasaniuc, S Sankararaman, G Bhatia, J Zhang, A Gusev, ...
Nature genetics 46 (12), 1356, 2014
542014
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