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Scott D. Larsen
Scott D. Larsen
Research Professor of Medicinal Chemistry
Подтвержден адрес электронной почты в домене med.umich.edu - Главная страница
Название
Процитировано
Процитировано
Год
Aza Diels-Alder reactions in aqueous solution: cyclocondensation of dienes with simple iminium salts generated under Mannich conditions
SD Larsen, PA Grieco
Journal of the American Chemical Society 107 (6), 1768-1769, 1985
3631985
X-ray structural and biological evaluation of a series of potent and highly selective inhibitors of human coronavirus papain-like proteases
YM Báez-Santos, SJ Barraza, MW Wilson, MP Agius, AM Mielech, ...
Journal of Medicinal Chemistry 57 (6), 2393-2412, 2014
2202014
Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β–induced fibrogenesis in human colonic myofibroblasts
LA Johnson, ES Rodansky, AJ Haak, SD Larsen, RR Neubig, ...
Inflammatory bowel diseases 20 (1), 154-165, 2014
1962014
Redox modification of nuclear actin by MICAL-2 regulates SRF signaling
MR Lundquist, AJ Storaska, TC Liu, SD Larsen, T Evans, RR Neubig, ...
Cell 156 (3), 563-576, 2014
1882014
Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis
TH Sisson, IO Ajayi, N Subbotina, AE Dodi, ES Rodansky, LN Chibucos, ...
The American journal of pathology 185 (4), 969-986, 2015
1672015
Investigation of potential bioisosteric replacements for the carboxyl groups of peptidomimetic inhibitors of protein tyrosine phosphatase 1B: identification of a tetrazole …
C Liljebris, SD Larsen, D Ogg, BJ Palazuk, JE Bleasdale
Journal of medicinal chemistry 45 (9), 1785-1798, 2002
1572002
Structure of methylguanidinium dihydrogen orthophosphate. Model compound for arginine-phosphate hydrogen bonding
FA Cotton, VW Day, EE Hazen, S Larsen
Journal of the American Chemical Society 95 (15), 4834-4840, 1973
1571973
Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence
H Zheng, CJ Colvin, BK Johnson, PD Kirchhoff, M Wilson, ...
Nature chemical biology 13 (2), 218-225, 2017
1532017
Hydroxylation of Enolates with Oxodiperoxymolybdenum(Pyridine)(Hexamethylphosphoric Triamide), MoO5·Py·HMPA(MoOPH): 3‐Hydroxy‐1,7,7‐Trimethylbicyclo …
E Vedejs, S Larsen
Organic Syntheses 64, 127-127, 2003
1402003
Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action
JE Bleasdale, D Ogg, BJ Palazuk, CS Jacob, ML Swanson, XY Wang, ...
Biochemistry 40 (19), 5642-5654, 2001
1232001
A pan-ALDH1A inhibitor induces necroptosis in ovarian cancer stem-like cells
I Chefetz, E Grimley, K Yang, L Hong, EV Vinogradova, R Suciu, ...
Cell reports 26 (11), 3061-3075. e6, 2019
1132019
Reactions of allylsilanes with simple iminium salts in water: A facile route to piperidines via a aminomethano desilylation-cyclization process
SD Larsen, PA Grieco, WF Fobare
Journal of the American Chemical Society 108 (12), 3512-3513, 1986
1131986
Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor–regulated gene transcription prevent fibrosis in a murine …
AJ Haak, PS Tsou, MA Amin, JH Ruth, P Campbell, DA Fox, D Khanna, ...
Journal of Pharmacology and Experimental Therapeutics 349 (3), 480-486, 2014
1092014
Aza Diels-Alder reactions in water: cyclocondensation of C-acyl iminium ions with cyclopentadiene
PA Grieco, SD Larsen, WF Fobare
Tetrahedron letters 27 (18), 1975-1978, 1986
1081986
Nonstabilized imidate ylides by the desilylation method: a route to the pyrrolizidine alkaloids retronecine and indicine
E Vedejs, S Larsen, FG West
The Journal of Organic Chemistry 50 (12), 2170-2174, 1985
1061985
Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B
SD Larsen, T Barf, C Liljebris, PD May, D Ogg, TJ O'Sullivan, BJ Palazuk, ...
Journal of medicinal chemistry 45 (3), 598-622, 2002
972002
Synthesis and biological activity of analogues of the antidiabetic/antiobesity agent 3-guanidinopropionic acid: discovery of a novel aminoguanidinoacetic acid antidiabetic agent
SD Larsen, MA Connell, MM Cudahy, BR Evans, PD May, MD Meglasson, ...
Journal of medicinal chemistry 44 (8), 1217-1230, 2001
972001
Novel Inhibitors of Staphylococcus aureus Virulence Gene Expression and Biofilm Formation
Y Ma, Y Xu, BD Yestrepsky, RJ Sorenson, M Chen, SD Larsen, H Sun
Public Library of Science 7 (10), e47255, 2012
942012
Optimization of novel nipecotic bis (amide) inhibitors of the Rho/MKL1/SRF transcriptional pathway as potential anti-metastasis agents
JL Bell, AJ Haak, SM Wade, PD Kirchhoff, RR Neubig, SD Larsen
Bioorganic & medicinal chemistry letters 23 (13), 3826-3832, 2013
862013
Biochemical importance of the binding of phosphate by arginyl groups. Model compounds containing methylguanidinium ion
FA Cotton, EE Hazen, VW Day, S Larsen, JG Norman, STK Wong, ...
Journal of the American Chemical Society 95 (7), 2367-2369, 1973
851973
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