The leptin-deficient (ob/ob) mouse: a new animal model of peripheral neuropathy of type 2 diabetes and obesity VR Drel, N Mashtalir, O Ilnytska, J Shin, F Li, VV Lyzogubov, IG Obrosova Diabetes 55 (12), 3335-3343, 2006 | 351 | 2006 |
High-fat diet–induced neuropathy of pre-diabetes and obesity: effects of “healthy” diet and aldose reductase inhibition IG Obrosova, O Ilnytska, VV Lyzogubov, IA Pavlov, N Mashtalir, JL Nadler, ... Diabetes 56 (10), 2598-2608, 2007 | 325 | 2007 |
Oxidative-nitrosative stress and poly (ADP-ribose) polymerase (PARP) activation in experimental diabetic neuropathy: the relation is revisited IG Obrosova, VR Drel, P Pacher, O Ilnytska, ZQ Wang, MJ Stevens, ... Diabetes 54 (12), 3435-3441, 2005 | 275 | 2005 |
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption M Rajesh, P Mukhopadhyay, S Bátkai, G Hasko, L Liaudet, VR Drel, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (1 …, 2007 | 249 | 2007 |
Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption M Rajesh, P Mukhopadhyay, S Bátkai, G Hasko, L Liaudet, VR Drel, ... American Journal of Physiology-Heart and Circulatory Physiology 293 (1 …, 2007 | 249 | 2007 |
Poly (ADP-ribose) polymerase inhibition alleviates experimental diabetic sensory neuropathy O Ilnytska, VV Lyzogubov, MJ Stevens, VR Drel, N Mashtalir, P Pacher, ... Diabetes 55 (6), 1686-1694, 2006 | 177 | 2006 |
Role of nitrosative stress in early neuropathy and vascular dysfunction in streptozotocin-diabetic rats IG Obrosova, VR Drel, CL Oltman, N Mashtalir, J Tibrewala, JT Groves, ... American Journal of Physiology-Endocrinology And Metabolism 293 (6), E1645-E1655, 2007 | 166 | 2007 |
A peroxynitrite decomposition catalyst counteracts sensory neuropathy in streptozotocin-diabetic mice VR Drel, P Pacher, I Vareniuk, I Pavlov, O Ilnytska, VV Lyzogubov, ... European journal of pharmacology 569 (1-2), 48-58, 2007 | 141 | 2007 |
PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy IG Obrosova, W Xu, VV Lyzogubov, O Ilnytska, N Mashtalir, I Vareniuk, ... Free Radical Biology and Medicine 44 (6), 972-981, 2008 | 132 | 2008 |
Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis VR Drel, P Pacher, TK Ali, J Shin, U Julius, AB El-Remessy, IG Obrosova International journal of molecular medicine 21 (6), 667-676, 2008 | 130 | 2008 |
Baicalein alleviates diabetic peripheral neuropathy through inhibition of oxidative–nitrosative stress and p38 MAPK activation R Stavniichuk, VR Drel, H Shevalye, Y Maksimchyk, TM Kuchmerovska, ... Experimental neurology 230 (1), 106-113, 2011 | 125 | 2011 |
Aldose reductase inhibition counteracts nitrosative stress and poly (ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells VR Drel, P Pacher, MJ Stevens, IG Obrosova Free Radical Biology and Medicine 40 (8), 1454-1465, 2006 | 121 | 2006 |
Early diabetes-induced biochemical changes in the retina: comparison of rat and mouse models IG Obrosova, VR Drel, AK Kumagai, C Szabo, P Pacher, MJ Stevens Diabetologia 49, 2525-2533, 2006 | 116 | 2006 |
Nicotinamide reverses neurological and neurovascular deficits in streptozotocin diabetic rats MJ Stevens, F Li, VR Drel, OI Abatan, H Kim, D Burnett, D Larkin, ... Journal of Pharmacology and Experimental Therapeutics 320 (1), 458-464, 2007 | 115 | 2007 |
Low-dose poly (ADP-ribose) polymerase inhibitor-containing combination therapies reverse early peripheral diabetic neuropathy F Li, VR Drel, C Szabo, MJ Stevens, IG Obrosova Diabetes 54 (5), 1514-1522, 2005 | 112 | 2005 |
New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-α VR Drel, S Lupachyk, H Shevalye, I Vareniuk, W Xu, J Zhang, ... Endocrinology 151 (6), 2547-2555, 2010 | 103 | 2010 |
PARP inhibition alleviates diabetes-induced systemic oxidative stress and neural tissue 4-hydroxynonenal adduct accumulation: correlation with peripheral nerve function S Lupachyk, H Shevalye, Y Maksimchyk, VR Drel, IG Obrosova Free Radical Biology and Medicine 50 (10), 1400-1409, 2011 | 99 | 2011 |
Nitrosative stress and peripheral diabetic neuropathy in leptin-deficient (ob/ob) mice I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, O Ilnytska, SR Bell, ... Experimental neurology 205 (2), 425-436, 2007 | 91 | 2007 |
Poly (ADP-ribose) polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats VR Drel, W Xu, J Zhang, PF Kador, TK Ali, J Shin, U Julius, B Slusher, ... Investigative ophthalmology & visual science 50 (4), 1778-1790, 2009 | 76 | 2009 |
Pathophysiology of gadolinium-associated systemic fibrosis B Wagner, V Drel, Y Gorin American Journal of Physiology-Renal Physiology 311 (1), F1-F11, 2016 | 74 | 2016 |