Підписатись
Barbara S. Slusher
Barbara S. Slusher
Professor of Neurology, Psychiatry, Neuroscience, Medicine, Oncology, Johns Hopkins University
Підтверджена електронна адреса в jhmi.edu - Домашня сторінка
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Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
SJ Dixon, DN Patel, M Welsch, R Skouta, ED Lee, M Hayano, AG Thomas, ...
elife 3, e02523, 2014
15332014
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells
A Le, AN Lane, M Hamaker, S Bose, A Gouw, J Barbi, T Tsukamoto, ...
Cell metabolism 15 (1), 110-121, 2012
11642012
HIV-associated neurocognitive disorder—pathogenesis and prospects for treatment
D Saylor, AM Dickens, N Sacktor, N Haughey, B Slusher, M Pletnikov, ...
Nature Reviews Neurology 12 (4), 234-248, 2016
9962016
Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
RD Leone, L Zhao, JM Englert, IM Sun, MH Oh, IH Sun, ML Arwood, ...
Science 366 (6468), 1013-1021, 2019
7302019
Abnormal excitatory neurotransmitter metabolism in schizophrenic brains
G Tsai, LA Passani, BS Slusher, R Carter, L Baer, JE Kleinman, JT Coyle
Archives of general psychiatry 52 (10), 829-836, 1995
6131995
Inhibition of glutaminase preferentially slows growth of glioma cells with mutant IDH1
MJ Seltzer, BD Bennett, AD Joshi, P Gao, AG Thomas, DV Ferraris, ...
Cancer research 70 (22), 8981-8987, 2010
5792010
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Y Xiang, ZE Stine, J Xia, Y Lu, RS O’Connor, BJ Altman, AL Hsieh, ...
The Journal of clinical investigation 125 (6), 2293-2306, 2015
4442015
Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury
BS Slusher, JJ Vornov, AG Thomas, PD Hurn, I Harukuni, A Bhardwaj, ...
Nature medicine 5 (12), 1396-1402, 1999
3691999
Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated α-linked acidic dipeptidase
PF Jackson, DC Cole, BS Slusher, SL Stetz, LE Ross, BA Donzanti, ...
Journal of medicinal chemistry 39 (2), 619-622, 1996
3611996
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer
JR Mesters, C Barinka, W Li, T Tsukamoto, P Majer, BS Slusher, ...
The EMBO journal 25 (6), 1375-1384, 2006
3372006
Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic …
SY Cho, KL Gage, RC Mease, S Senthamizhchelvan, DP Holt, ...
Journal of Nuclear Medicine 53 (12), 1883-1891, 2012
3292012
Palonosetron exhibits unique molecular interactions with the 5-HT3 receptor
C Rojas, M Stathis, AG Thomas, EB Massuda, J Alt, J Zhang, ...
Anesthesia & Analgesia 107 (2), 469-478, 2008
2852008
Targeting glutamine metabolism enhances tumor-specific immunity by modulating suppressive myeloid cells
MH Oh, IH Sun, L Zhao, RD Leone, IM Sun, W Xu, SL Collins, AJ Tam, ...
The Journal of clinical investigation 130 (7), 3865-3884, 2020
2542020
Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer
C Barinka, C Rojas, B Slusher, M Pomper
Current medicinal chemistry 19 (6), 856-870, 2012
2412012
Palonosetron triggers 5-HT3 receptor internalization and causes prolonged inhibition of receptor function
C Rojas, AG Thomas, J Alt, M Stathis, J Zhang, EB Rubenstein, ...
European journal of pharmacology 626 (2-3), 193-199, 2010
2312010
Design, synthesis, and pharmacological evaluation of bis-2-(5-phenylacetamido-1, 2, 4-thiadiazol-2-yl) ethyl sulfide 3 (BPTES) analogs as glutaminase inhibitors
K Shukla, DV Ferraris, AG Thomas, M Stathis, B Duvall, G Delahanty, J Alt, ...
Journal of medicinal chemistry 55 (23), 10551-10563, 2012
2282012
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer
A Elgogary, Q Xu, B Poore, J Alt, SC Zimmermann, L Zhao, J Fu, B Chen, ...
Proceedings of the National Academy of Sciences 113 (36), E5328-E5336, 2016
2152016
Preventing allograft rejection by targeting immune metabolism
CF Lee, YC Lo, CH Cheng, GJ Furtmüller, B Oh, V Andrade-Oliveira, ...
Cell reports 13 (4), 760-770, 2015
1962015
In vitro and in vivo radiosensitization of glioblastoma cells by the poly (ADP-ribose) polymerase inhibitor E7016
AL Russo, HC Kwon, WE Burgan, D Carter, K Beam, X Weizheng, ...
Clinical Cancer Research 15 (2), 607-612, 2009
1872009
Rat brain N-acetylated alpha-linked acidic dipeptidase activity. Purification and immunologic characterization.
BS Slusher, MB Robinson, G Tsai, ML Simmons, SS Richards, JT Coyle
Journal of Biological Chemistry 265 (34), 21297-21301, 1990
1851990
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