Подписаться
József Dobó
József Dobó
Institute of Enzymology, HUN-REN Research Centre for Natural Sciences, Hungarian Academy of Sciences
Подтвержден адрес электронной почты в домене ttk.mta.hu
Название
Процитировано
Процитировано
Год
Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2
D Héja, A Kocsis, J Dobó, K Szilágyi, R Szász, P Závodszky, G Pál, P Gál
Proceedings of the National Academy of Sciences 109 (26), 10498-10503, 2012
2562012
MASP-1, a promiscuous complement protease: structure of its catalytic region reveals the basis of its broad specificity
J Dobó, V Harmat, L Beinrohr, E Sebestyén, P Závodszky, P Gál
The Journal of Immunology 183 (2), 1207-1214, 2009
1592009
Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of α1-proteinase inhibitor with porcine pancreatic elastase
A Dementiev, J Dobó, PGW Gettins
Journal of Biological Chemistry 281 (6), 3452-3457, 2006
1592006
C1 inhibitor serpin domain structure reveals the likely mechanism of heparin potentiation and conformational disease
L Beinrohr, V Harmat, J Dobó, Z Loörincz, P Gál, P Závodszky
Journal of Biological Chemistry 282 (29), 21100-21109, 2007
1332007
Effects of MASP-1 of the complement system on activation of coagulation factors and plasma clot formation
K Hess, R Ajjan, F Phoenix, J Dobó, P Gál, V Schroeder
PloS one 7 (4), e35690, 2012
1312012
Early complement proteases: C1r, C1s and MASPs. A structural insight into activation and functions
P Gál, J Dobó, P Závodszky, RBM Sim
Molecular immunology 46 (14), 2745-2752, 2009
1312009
MASP-3 is the exclusive pro-factor D activator in resting blood: the lectin and the alternative complement pathways are fundamentally linked
J Dobó, D Szakács, G Oroszlán, E Kortvely, B Kiss, E Boros, R Szász, ...
Scientific reports 6 (1), 31877, 2016
1262016
Cleavage of kininogen and subsequent bradykinin release by the complement component: mannose-binding lectin-associated serine protease (MASP)-1
J Dobó, B Major, KA Kékesi, I Szabó, M Megyeri, K Hajela, G Juhász, ...
PloS one 6 (5), e20036, 2011
1222011
Structural basis for activation of the complement system by component C4 cleavage
RT Kidmose, NS Laursen, J Dobó, TR Kjaer, S Sirotkina, L Yatime, ...
Proceedings of the National Academy of Sciences 109 (38), 15425-15430, 2012
1212012
C1, MBL–MASPs and C1-inhibitor: novel approaches for targeting complement-mediated inflammation
L Beinrohr, J Dobó, P Závodszky, P Gál
Trends in molecular medicine 14 (12), 511-521, 2008
1162008
Multiple roles of complement MASP-1 at the interface of innate immune response and coagulation
J Dobó, V Schroeder, L Jenny, L Cervenak, P Závodszky, P Gál
Molecular immunology 61 (2), 69-78, 2014
1102014
Biological variations of MASP-3 and MAp44, two splice products of the MASP1 gene involved in regulation of the complement system
SE Degn, L Jensen, P Gál, J Dobó, SH Holmvad, JC Jensenius, S Thiel
Journal of immunological methods 361 (1-2), 37-50, 2010
1082010
The emerging roles of mannose‐binding lectin‐associated serine proteases (MASP s) in the lectin pathway of complement and beyond
J Dobó, G Pál, L Cervenak, P Gál
Immunological reviews 274 (1), 98-111, 2016
1002016
Mannan-binding lectin (MBL)-associated serine protease-1 (MASP-1), a serine protease associated with humoral pattern-recognition molecules: normal and acute-phase levels in …
S Thiel, L Jensen, SE Degn, HJ Nielsen, P Gál, J Dobó, JC Jensenius
Clinical & Experimental Immunology 169 (1), 38-48, 2012
982012
Monospecific inhibitors show that both mannan-binding lectin-associated serine protease-1 (MASP-1) and-2 are essential for lectin pathway activation and reveal structural …
D Héja, V Harmat, K Fodor, M Wilmanns, J Dobó, KA Kékesi, P Závodszky, ...
Journal of Biological Chemistry 287 (24), 20290-20300, 2012
982012
Activities of the MBL-associated serine proteases (MASPs) and their regulation by natural inhibitors
NKH Wong, M Kojima, J Dobo, G Ambrus, RB Sim
Molecular immunology 36 (13-14), 853-861, 1999
981999
The control of the complement lectin pathway activation revisited: both C1-inhibitor and antithrombin are likely physiological inhibitors, while α2-macroglobulin is not
K Paréj, J Dobó, P Závodszky, P Gál
Molecular immunology 54 (3-4), 415-422, 2013
932013
Selective inhibition of the lectin pathway of complement with phage display selected peptides against mannose-binding lectin-associated serine protease (MASP)-1 and-2 …
A Kocsis, KA Kékesi, R Szász, BM Végh, J Balczer, J Dobó, P Závodszky, ...
The Journal of Immunology 185 (7), 4169-4178, 2010
892010
Quantitative characterization of the activation steps of mannan-binding lectin (MBL)-associated serine proteases (MASPs) points to the central role of MASP-1 in the initiation …
M Megyeri, V Harmat, B Major, Á Végh, J Balczer, D Héja, K Szilágyi, ...
Journal of Biological Chemistry 288 (13), 8922-8934, 2013
792013
Be on target: strategies of targeting alternative and lectin pathway components in complement-mediated diseases
J Dobó, A Kocsis, P Gál
Frontiers in Immunology 9, 402108, 2018
742018
В данный момент система не может выполнить эту операцию. Повторите попытку позднее.
Статьи 1–20