Single atom substitution in mouse protein kinase G eliminates oxidant sensing to cause hypertension O Prysyazhna, O Rudyk, P Eaton Nature medicine 18 (2), 286-290, 2012 | 192 | 2012 |
Biochemical methods for monitoring protein thiol redox states in biological systems O Rudyk, P Eaton Redox biology 2, 803-813, 2014 | 142 | 2014 |
Protection from hypertension in mice by the Mediterranean diet is mediated by nitro fatty acid inhibition of soluble epoxide hydrolase RL Charles, O Rudyk, O Prysyazhna, A Kamynina, J Yang, C Morisseau, ... Proceedings of the National Academy of Sciences 111 (22), 8167-8172, 2014 | 108 | 2014 |
Protein kinase G Iα oxidation paradoxically underlies blood pressure lowering by the reductant hydrogen sulfide D Stubbert, O Prysyazhna, O Rudyk, J Scotcher, JR Burgoyne, P Eaton Hypertension 64 (6), 1344-1351, 2014 | 105 | 2014 |
cGMP-dependent activation of protein kinase G precludes disulfide activation: implications for blood pressure control JR Burgoyne, O Prysyazhna, O Rudyk, P Eaton Hypertension 60 (5), 1301-1308, 2012 | 91 | 2012 |
Protein kinase G oxidation is a major cause of injury during sepsis O Rudyk, A Phinikaridou, O Prysyazhna, JR Burgoyne, RM Botnar, ... Proceedings of the National Academy of Sciences 110 (24), 9909-9913, 2013 | 64 | 2013 |
Experimental hyperleptinemia in neonatal rats leads to selective leptin responsiveness, hypertension, and altered myocardial function AM Samuelsson, J Clark, O Rudyk, MJ Shattock, SE Bae, T South, ... Hypertension 62 (3), 627-633, 2013 | 62 | 2013 |
Nitroglycerin fails to lower blood pressure in redox-dead Cys42Ser PKG1α knock-in mouse O Rudyk, O Prysyazhna, JR Burgoyne, P Eaton Circulation 126 (3), 287-295, 2012 | 60 | 2012 |
Deficient angiogenesis in redox-dead Cys17Ser PKARIα knock-in mice JR Burgoyne, O Rudyk, H Cho, O Prysyazhna, N Hathaway, A Weeks, ... Nature communications 6 (1), 7920, 2015 | 53 | 2015 |
Disulfide-activated protein kinase G Iα regulates cardiac diastolic relaxation and fine-tunes the Frank–Starling response J Scotcher, O Prysyazhna, A Boguslavskyi, K Kistamas, N Hadgraft, ... Nature communications 7 (1), 13187, 2016 | 52 | 2016 |
Aging-related increase of sensitivity of the mitochondrial permeability transition pore to inductors in the rat heart VF Sahach, HL Vavilova, NA Strutyns' ka, OV Rudyk Fiziolohichnyi Zhurnal (Kiev, Ukraine: 1994) 50 (2), 49-63, 2004 | 32 | 2004 |
Quantification of microcirculatory blood flow: a sensitive and clinically relevant prognostic marker in murine models of sepsis CA Sand, A Starr, CDE Wilder, O Rudyk, D Spina, C Thiemermann, ... Journal of Applied Physiology 118 (3), 344-354, 2015 | 31 | 2015 |
Redox-dependent dimerization of p38α mitogen-activated protein kinase with mitogen-activated protein kinase kinase 3 R Bassi, JR Burgoyne, GF DeNicola, O Rudyk, V DeSantis, RL Charles, ... Journal of biological chemistry 292 (39), 16161-16173, 2017 | 29 | 2017 |
Increased cardiovascular reactivity to acute stress and salt-loading in adult male offspring of fat fed non-obese rats O Rudyk, P Makra, E Jansen, MJ Shattock, L Poston, PD Taylor PloS one 6 (10), e25250, 2011 | 28 | 2011 |
Nitrosative protein oxidation is modulated during early endotoxemia JR Burgoyne, O Rudyk, M Mayr, P Eaton Nitric Oxide 25 (2), 118-124, 2011 | 23 | 2011 |
Oxidation of PKGIα mediates an endogenous adaptation to pulmonary hypertension O Rudyk, A Rowan, O Prysyazhna, S Krasemann, K Hartmann, M Zhang, ... Proceedings of the National Academy of Sciences 116 (26), 13016-13025, 2019 | 21 | 2019 |
Anti-proliferative actions of T-type calcium channel inhibition in Thy1 nephritis A Cove-Smith, CJ Mulgrew, O Rudyk, N Dutt, LM McLatchie, MJ Shattock, ... The American journal of pathology 183 (2), 391-401, 2013 | 21 | 2013 |
Melatonin recovers ischemic tolerance and decreases the sensitivity of mitochondrial permeability transition pore opening in the heart of aging rats VF Sahach, OV Rudyk, HL Vavilova, AV Kotsiuruba, T IuP Fiziolohichnyi Zhurnal (Kiev, Ukraine: 1994) 52 (3), 3-14, 2006 | 19 | 2006 |
Inhibition of mitochondrial permeability transition pore is one of the mechanisms of cardioprotective effect of coenzyme Q10 VF Sahach, HL Vavilova, OV Rudyk, FV Dobrovol's' kyĭ, TV Shymans' ka, ... Fiziolohichnyi Zhurnal (Kiev, Ukraine: 1994) 53 (4), 35-42, 2007 | 18 | 2007 |
Phospholemman phosphorylation regulates vascular tone, blood pressure, and hypertension in mice and humans A Boguslavskyi, S Tokar, O Prysyazhna, O Rudyk, D Sanchez-Tatay, ... Circulation 143 (11), 1123-1138, 2021 | 14 | 2021 |