Continuous‐flow technology—a tool for the safe manufacturing of active pharmaceutical ingredients B Gutmann, D Cantillo, CO Kappe Angewandte Chemie International Edition 54 (23), 6688-6728, 2015 | 1379 | 2015 |
Microwave chemistry in silicon carbide reaction vials: separating thermal from nonthermal effects D Obermayer, B Gutmann, CO Kappe Angewandte Chemie International Edition 48 (44), 8321-8324, 2009 | 325 | 2009 |
Synthesis of 5‐Substituted 1H‐Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High‐Temperature Microreactor Approach B Gutmann, JP Roduit, D Roberge, CO Kappe Angewandte Chemie International Edition 49 (39), 7101-7105, 2010 | 234 | 2010 |
Continuous flow generation and reactions of anhydrous diazomethane using a teflon AF-2400 tube-in-tube reactor F Mastronardi, B Gutmann, CO Kappe Organic letters 15 (21), 5590-5593, 2013 | 210 | 2013 |
Kontinuierliche Durchflussverfahren: ein Werkzeug für die sichere Synthese von pharmazeutischen Wirkstoffen B Gutmann, D Cantillo, CO Kappe Angewandte Chemie 127 (23), 6788-6832, 2015 | 154 | 2015 |
Mechanistic insights on azide− nitrile cycloadditions: on the dialkyltin oxide− trimethylsilyl azide route and a new Vilsmeier− Haack-type organocatalyst D Cantillo, B Gutmann, CO Kappe Journal of the American Chemical Society 133 (12), 4465-4475, 2011 | 132 | 2011 |
Sintered Silicon Carbide: A New Ceramic Vessel Material for Microwave Chemistry in Single‐Mode Reactors B Gutmann, D Obermayer, B Reichart, B Prekodravac, M Irfan, ... Chemistry–A European Journal 16 (40), 12182-12194, 2010 | 124 | 2010 |
Straightforward strategies for the preparation of NH-sulfoximines: a serendipitous story JA Bull, L Degennaro, R Luisi Synlett 28 (19), 2525-2538, 2017 | 122 | 2017 |
The concept of chemical generators: on-site on-demand production of hazardous reagents in continuous flow D Dallinger, B Gutmann, CO Kappe Accounts of chemical research 53 (7), 1330-1341, 2020 | 121 | 2020 |
Continuous flow synthesis of α-halo ketones: essential building blocks of antiretroviral agents VD Pinho, B Gutmann, LSM Miranda, ROMA De Souza, CO Kappe The Journal of Organic Chemistry 79 (4), 1555-1562, 2014 | 115 | 2014 |
Activation and deactivation of a chemical transformation by an electromagnetic field: evidence for specific microwave effects in the formation of Grignard reagents B Gutmann, AM Schwan, B Reichart, C Gspan, F Hofer, CO Kappe Angewandte Chemie 33 (123), 7778-7782, 2011 | 107 | 2011 |
Forbidden chemistries—paths to a sustainable future engaging continuous processing B Gutmann, CO Kappe Journal of Flow Chemistry 7 (3-4), 65-71, 2017 | 99 | 2017 |
Characterization of Microwave‐Induced Electric Discharge Phenomena in Metal–Solvent Mixtures W Chen, B Gutmann, CO Kappe ChemistryOpen 1 (1), 39-48, 2012 | 92 | 2012 |
Design and 3D printing of a stainless steel reactor for continuous difluoromethylations using fluoroform B Gutmann, M Köckinger, G Glotz, T Ciaglia, E Slama, M Zadravec, ... Reaction Chemistry & Engineering 2 (6), 919-927, 2017 | 90 | 2017 |
Homogeneous liquid-phase oxidation of ethylbenzene to acetophenone in continuous flow mode B Gutmann, P Elsner, D Roberge, CO Kappe Acs Catalysis 3 (12), 2669-2676, 2013 | 72 | 2013 |
Laboratory-scale membrane reactor for the generation of anhydrous diazomethane D Dallinger, VD Pinho, B Gutmann, CO Kappe The Journal of Organic Chemistry 81 (14), 5814-5823, 2016 | 63 | 2016 |
Development of a continuous flow sulfoxide imidation protocol using azide sources under superacidic conditions B Gutmann, P Elsner, A O’Kearney-McMullan, W Goundry, DM Roberge, ... Organic Process Research & Development 19 (8), 1062-1067, 2015 | 60 | 2015 |
Continuous-flow synthesis of adipic acid from cyclohexene using hydrogen peroxide in high-temperature explosive regimes. M Damm, B Gutmann, CO Kappe ChemSusChem 6 (6), 2013 | 60 | 2013 |
Continuous flow synthesis of β-amino acids from α-amino acids via Arndt–Eistert homologation VD Pinho, B Gutmann, CO Kappe RSC advances 4 (70), 37419-37422, 2014 | 59 | 2014 |
Toward the Synthesis of Noroxymorphone via Aerobic Palladium-Catalyzed Continuous Flow N-Demethylation Strategies B Gutmann, P Elsner, DP Cox, U Weigl, DM Roberge, CO Kappe ACS Sustainable Chemistry & Engineering 4 (11), 6048-6061, 2016 | 48 | 2016 |