|Smad regulation in TGF-β signal transduction|
A Moustakas, S Souchelnytskyi, CH Heldin
Journal of cell science 114 (24), 4359-4369, 2001
|TGF‐β receptor‐mediated signalling through Smad2, Smad3 and Smad4|
A Nakao, T Imamura, S Souchelnytskyi, M Kawabata, A Ishisaki, E Oeda, ...
The EMBO journal 16 (17), 5353-5362, 1997
|Phosphorylation of Ser465 and Ser467 in the C terminus of Smad2 mediates interaction with Smad4 and is required for transforming growth factor-β signaling|
S Souchelnytskyi, K Tamaki, U Engström, C Wernstedt, P ten Dijke, ...
Journal of Biological Chemistry 272 (44), 28107-28115, 1997
|The L45 loop in type I receptors for TGF‐β family members is a critical determinant in specifying Smad isoform activation|
U Persson, H Izumi, S Souchelnytskyi, S Itoh, S Grimsby, U Engström, ...
FEBS letters 434 (1-2), 83-87, 1998
|Regulation of Smad signaling by protein kinase C|
I Yakymovych, P ten Dijke, CH Heldin, S Souchelnytskyi
The FASEB Journal 15 (3), 553-555, 2001
|Identification of Smad2, a human Mad-related protein in the transforming growth factor β signaling pathway|
A Nakao, E Röijer, T Imamura, S Souchelnytskyi, G Stenman, CH Heldin, ...
Journal of Biological Chemistry 272 (5), 2896-2900, 1997
|Physical and Functional Interaction of Murine andXenopus Smad7 with Bone Morphogenetic Protein Receptors and Transforming Growth Factor-β Receptors|
S Souchelnytskyi, T Nakayama, A Nakao, A Morén, CH Heldin, ...
Journal of Biological Chemistry 273 (39), 25364-25370, 1998
|Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site|
Y Wallez, F Cand, F Cruzalegui, C Wernstedt, S Souchelnytskyi, I Vilgrain, ...
Oncogene 26 (7), 1067-1077, 2007
|Phosphorylation of Ser165 in TGF‐beta type I receptor modulates TGF‐beta1‐induced cellular responses.|
S Souchelnytskyi, P Ten Dijke, K Miyazono, CH Heldin
The EMBO journal 15 (22), 6231-6240, 1996
|Frequent loss of SMAD4/DPC4 protein in colorectal cancers|
R Salovaara, S Roth, A Loukola, V Launonen, P Sistonen, E Avizienyte, ...
Gut 51 (1), 56-59, 2002
|Functional proteomics of transforming growth factor‐β1‐stimulated Mv1Lu epithelial cells: Rad51 as a target of TGFβ1‐dependent regulation of DNA repair|
T Kanamoto, U Hellman, CH Heldin, S Souchelnytskyi
The EMBO journal 21 (5), 1219-1230, 2002
|Expression of Smad proteins in human colorectal cancer|
O Korchynskyi, M Landström, R Stoika, K Funa, CH Heldin, P ten Dijke, ...
International journal of cancer 82 (2), 197-202, 1999
|Proteins associated with type II bone morphogenetic protein receptor (BMPR‐II) and identified by two‐dimensional gel electrophoresis and mass spectrometry|
S Hassel, A Eichner, M Yakymovych, U Hellman, P Knaus, ...
Proteomics 4 (5), 1346-1358, 2004
|Cancer biomarker discovery: current status and future perspectives|
K Mäbert, M Cojoc, C Peitzsch, I Kurth, S Souchelnytskyi, A Dubrovska
International journal of radiation biology 90 (8), 659-677, 2014
|Monoclonal antibody MX35 detects the membrane transporter NaPi2b (SLC34A2) in human carcinomas|
BWT Yin, R Kiyamova, R Chua, OL Caballero, I Gout, V Gryshkova, ...
Cancer Immunity: a Journal of the Academy of Cancer Immunology 8, 2008
|Intracellular signaling of osteogenic protein‐1 through Smad5 activation|
K Tamaki, S Souchelnytskyi, S Itoh, A Nakao, K Sampath, CH Heldin, ...
Journal of cellular physiology 177 (2), 355-363, 1998
|Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients|
M Lomnytska, A Dubrovska, U Hellman, N Volodko, S Souchelnytskyi
International journal of cancer 118 (2), 412-421, 2006
|Efficient enrichment of intact phosphorylated proteins by modified immobilized metal‐affinity chromatography|
A Dubrovska, S Souchelnytskyi
Proteomics 5 (18), 4678-4683, 2005
|Bridging proteomics and systems biology: what are the roads to be traveled?|
Proteomics 5 (16), 4123-4137, 2005
|Proteomics‐based identification of proteins interacting with Smad3: SREBP‐2 forms a complex with Smad3 and inhibits its transcriptional activity|
S Grimsby, H Jaensson, A Dubrovska, M Lomnytska, U Hellman, ...
FEBS letters 577 (1-2), 93-100, 2004