| Principles of bioactive lipid signalling: lessons from sphingolipids YA Hannun, LM Obeid Nature reviews Molecular cell biology 9 (2), 139-150, 2008 | 3708 | 2008 |
| Programmed cell death induced by ceramide LM Obeid, CM Linardic, LA Karolak, YA Hannun Science 259 (5102), 1769-1771, 1993 | 2233 | 1993 |
| Sphingolipids and their metabolism in physiology and disease YA Hannun, LM Obeid Nature reviews Molecular cell biology 19 (3), 175-191, 2018 | 1448 | 2018 |
| An overview of sphingolipid metabolism: from synthesis to breakdown CR Gault, LM Obeid, YA Hannun Sphingolipids as signaling and regulatory molecules, 1-23, 2010 | 1209 | 2010 |
| The ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind YA Hannun, LM Obeid Journal of Biological Chemistry 277 (29), 25847-25850, 2002 | 1134 | 2002 |
| Ceramide: an intracellular signal for apoptosis YA Hannun, LM Obeid Trends in biochemical sciences 20 (2), 73-77, 1995 | 792 | 1995 |
| Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation. MY Kim, C Linardic, L Obeid, Y Hannun Journal of Biological Chemistry 266 (1), 484-489, 1991 | 779 | 1991 |
| Many ceramides YA Hannun, LM Obeid Journal of Biological Chemistry 286 (32), 27855-27862, 2011 | 641 | 2011 |
| Role for Ceramide in Cell Cycle Arrest (∗) S Jayadev, B Liu, AE Bielawska, JY Lee, F Nazaire, MY Pushkareva, ... Journal of Biological Chemistry 270 (5), 2047-2052, 1995 | 607 | 1995 |
| Role of ceramide in cellular senescence (∗) ME Venable, JY Lee, MJ Smyth, A Bielawska, LM Obeid Journal of Biological Chemistry 270 (51), 30701-30708, 1995 | 601 | 1995 |
| Ceramide synthases at the centre of sphingolipid metabolism and biology TD Mullen, YA Hannun, LM Obeid Biochemical Journal 441 (3), 789-802, 2012 | 541 | 2012 |
| Sphingolipid metabolism cooperates with BAK and BAX to promote the mitochondrial pathway of apoptosis JE Chipuk, GP McStay, A Bharti, T Kuwana, CJ Clarke, LJ Siskind, ... Cell 148 (5), 988-1000, 2012 | 468 | 2012 |
| Ceramidases: regulators of cellular responses mediated by ceramide, sphingosine, and sphingosine-1-phosphate C Mao, LM Obeid Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2008 | 466 | 2008 |
| Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2 P Zhang, B Liu, MS Seo, SG Rhee, LM Obeid Journal of biological chemistry 272 (49), 30615-30618, 1997 | 460 | 1997 |
| Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-α-induced cell death B Liu, N Andrieu-Abadie, T Levade, P Zhang, LM Obeid, YA Hannun Journal of Biological Chemistry 273 (18), 11313-11320, 1998 | 419 | 1998 |
| De Novo Ceramide Regulates the Alternative Splicing of Caspase 9 and Bcl-x in A549 Lung Adenocarcinoma Cells: DEPENDENCE ON PROTEIN PHOSPHATASE-1∗ CE Chalfant, K Rathman, RL Pinkerman, RE Wood, LM Obeid, ... Journal of Biological Chemistry 277 (15), 12587-12595, 2002 | 409 | 2002 |
| The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE2 production in response to TNF‐α BJ Pettus, J Bielawski, AM Porcelli, DL Reames, KR Johnson, J Morrow, ... The FASEB Journal 17 (11), 1411-1421, 2003 | 405 | 2003 |
| Selectivity of ceramide-mediated biology. Lack of activity of erythro-dihydroceramide. A Bielawska, HM Crane, D Liotta, LM Obeid, YA Hannun Journal of Biological Chemistry 268 (35), 26226-26232, 1993 | 402 | 1993 |
| Bcl-2 interrupts the ceramide-mediated pathway of cell death. J Zhang, N Alter, JC Reed, C Borner, LM Obeid, YA Hannun Proceedings of the National Academy of Sciences 93 (11), 5325-5328, 1996 | 385 | 1996 |
| Regulation of protein kinase C and role in cancer biology GC Blobe, LM Obeid, YA Hannun Cancer and Metastasis Reviews 13, 411-431, 1994 | 383 | 1994 |
