Лега Дмитро Олександрович, Лега Дмитрий Александрович, Lega Dmitry Alexandrovich ORCID 000-0002-4505
Лега Дмитро Олександрович, Лега Дмитрий Александрович, Lega Dmitry Alexandrovich ORCID 000-0002-4505
National University of Pharmacy
Verified email at nuph.edu.ua
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Year
Peculiarities of 2-amino-3-R-4-aryl-4 H-pyranes multicomponent synthesis derived from 1 H-2, 1-benzothiazin-4 (3 H)-one 2, 2-dioxide
DA Lega, NY Gorobets, VP Chernykh, SV Shishkina, LA Shemchuk
RSC advances 6 (19), 16087-16099, 2016
182016
An efficient, three-component synthesis and molecular structure of derivatives of 2-amino-3-R-6-ethyl-4,6-dihydropyrano[3,2-c][2,1]benzothiazine-5,5-dioxide …
LA Shemchuk, DA Lega, RG Redkin, VP Chernykh, OV Shishkin, ...
Tetrahedron 70 (44), 8348-8353, 2014
162014
The study of the three-component interaction between 1-ethyl-1H-2, 1-benzothiazin-4 (3H)-one 2, 2-dioxide, heterylcarbaldehydes and active methylene nitriles
DA Lega, VP Chernykh, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 14 (1 (53)), 6-16, 2016
92016
Synthesis of 1-ethyl-1H-2,1-benzothiazine 2,2-dioxide derivatives using cycloalkanecarbaldehydes and evaluation of their antimicrobial activity
DA Lega, VP Chernykh, L Zaprutko, AK Gzella, LA Shemchuk
Chemistry of Heterocyclic Compounds 53 (2), 219-229, 2017
82017
1, 2-Benzoxathiin-4 (3 H)-one 2, 2-dioxide–new enol nucleophile in three-component interaction with benzaldehydes and active methylene nitriles
GV Grygoriv, DA Lega, VP Chernykh, L Zaprutko, AK Gzella, A Pawełczyk, ...
RSC advances 8 (65), 37295-37302, 2018
62018
The synthesis, anti-inflammatory, analgesic and antimicrobial activities of ethyl 2-amino-4-alkyl-4, 6-dihydropyrano [3, 2c][2, 1] benzothiazin-3-carboxylate 5, 5-dioxides and …
DA Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ...
Journal of Organic and Pharmaceutical Chemistry 14 (4 (56)), 3-11, 2016
62016
Antimicrobial, anti-inflammatory and analgesic activities of 2-amino-6-ethyl-4, 6-dihydropyrano| 3, 2-c|| 2, 1| benzothiazine 5, 5-dioxides and triethylammonium 3-| 1-(4 …
DO Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ...
Вісник фармації, 61-69, 2016
42016
Synthesis of novel spiro-condensed 2-amino-4 H-pyrans based on 1, 2-benzoxathiin-4 (3 H)-one 2, 2-dioxide
GV Grygoriv, DA Lega, L Zaprutko, AK Gzella, E Wieczorek-Dziurla, ...
Chemistry of Heterocyclic Compounds 55 (3), 254-260, 2019
32019
Synthesis of 1, 2-benzoxathiine 2, 2-dioxide derivatives using aliphatic aldehydes and assessment of their antimicrobial activity
GV Grygoriv, DO Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
32017
Domino-reactions of 1, 2-benzoxathiin-4 (3H)-one 2, 2-dioxide, hetarenecarbaldehydes and active methylene nitriles in the construction of new 2-amino-4H-pyrans and the study of …
GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
22018
The use of aliphatic aldehydes in the synthesis of new pyran annulated derivatives of 1h-2, 1-benzothiazin-4-one 2, 2-dioxide via domino-type interactions. The antimicrobial …
DA Lega, NI Filimonova, OG Geyderikh, VP Chernykh, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 14 (2 (54)), 29-40, 2016
22016
Spiro [benzo [е] pyrano [3, 2-c][1, 2] oxathiin-4, 3’-indolil]-3-carbonitrile 5, 5-dioxides: synthesis and the biological activity study
GV Grygoriv, DA Lega, IA Zupanets, SK Shebeko, SM Zimin, ...
12019
The synthesis of 2-amino-4-aryl-4H-pyrano| 3, 2-c|| 1, 2| benzoxathiine-3-carbonitrile 5, 5-dioxides and the study of their effect on the blood coagulation process
GV Grygoriv, DA Lega, LM Shemchuk, LM Maloshtan, GS Kalenichenko, ...
Вісник фармації, 3-8, 2018
12018
Cycloalkanecarbaldehydes in synthesis of novel 1, 2-benzoxathiin-4 (3H)-on 2, 2-dioxide derivatives and study of the antimicrobial activity of synthesized compounds
GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
12017
In vitro antimicrobial activity evaluation of 2-amino-3-r-6-ethyl-4, 6-dihydropyrano [3, 2-c][2, 1] benzothiazine 5, 5-dioxides with 4-aryl substituent and spirofused with 2 …
DA Lega, NI Filimonova, HM Dikaya, VP Chernykh, LA Shemchuk
Ukrainian biopharmaceutical journal, 24-32, 2016
12016
The synthesis and antiviral activity against yellow fewer virus of 2-(4, 6-di (pyrrolidin-1-yl)-1, 3, 5-triazin-2-yl)-N-(alkyl, aryl) hydrazine-1-carbothioamides
V Moskalenko, OI Barchina, SA Tsyhankov, DA Lega, YA Fedchenkova, ...
Journal of Organic and Pharmaceutical Chemistry 19 (2 (74)), 36-43, 2021
2021
1, 2-Benzoxathiin-4 (3H)-one 2, 2-dioxide–an underinvestigated building block with a high synthetic and pharmacological potential: synthesis, chemical properties, biological …
HV Hryhoriv, DA Lega, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 19 (2 (74)), 4-28, 2021
2021
2-Amino-4-(4-chloro-1-ethyl-2, 2-dioxo-1H-benzo [c][1, 2] thiazin-3-yl)-7, 7-dimethyl-5-oxo-5, 6, 7, 8-tetrahydro-4H-chromene-3-carbonitrile: single-crystal X-ray diffraction …
MO Shyshkina, DA Lega, VD Goryachiy, LM Shemchuk, DV Levashov, ...
Acta Crystallographica Section E: Crystallographic Communications 77 (3 …, 2021
2021
The synthesis of new heterocyclic assembly comprising powerful Pharmacophoric moieties of 2-amino-4H-pyran, 1H-2, 1-benzothiazine 2, 2-dioxide and quinolin-2 (1H)-one
TI Kolodiazhna, DA Lega, KM Sytnik, LA Shemchuk
2021
Synthesis of bis-condensed 1, 4-dihydropyridines containing 2H-chromen-2-one and 2, 1-benzothiazine 2, 2-dioxide moieties
DA Lega, KM Sytnik, TV Spychak, LA Shemchuk
НФаУ, 2021
2021
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