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Лега Дмитро Олександрович, Лега Дмитрий Александрович, Lega Dmitry Alexandrovich ORCID 000-0002-4505
Лега Дмитро Олександрович, Лега Дмитрий Александрович, Lega Dmitry Alexandrovich ORCID 000-0002-4505
National University of Pharmacy
Подтвержден адрес электронной почты в домене nuph.edu.ua
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Год
Peculiarities of 2-amino-3-R-4-aryl-4 H-pyranes multicomponent synthesis derived from 1 H-2, 1-benzothiazin-4 (3 H)-one 2, 2-dioxide
DA Lega, NY Gorobets, VP Chernykh, SV Shishkina, LA Shemchuk
RSC advances 6 (19), 16087-16099, 2016
192016
An efficient, three-component synthesis and molecular structure of derivatives of 2-amino-3-R-6-ethyl-4,6-dihydropyrano[3,2-c][2,1]benzothiazine-5,5-dioxide …
LA Shemchuk, DA Lega, RG Redkin, VP Chernykh, OV Shishkin, ...
Tetrahedron 70 (44), 8348-8353, 2014
172014
The study of the three-component interaction between 1-ethyl-1H-2, 1-benzothiazin-4 (3H)-one 2, 2-dioxide, heterylcarbaldehydes and active methylene nitriles
DA Lega, VP Chernykh, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 14 (1 (53)), 6-16, 2016
102016
Synthesis of 1-ethyl-1H-2, 1-benzothiazine 2, 2-dioxide derivatives using cycloalkanecarbaldehydes and evaluation of their antimicrobial activity
DA Lega, VP Chernykh, L Zaprutko, AK Gzella, LA Shemchuk
Chemistry of Heterocyclic Compounds 53 (2), 219-229, 2017
92017
1, 2-Benzoxathiin-4 (3 H)-one 2, 2-dioxide–new enol nucleophile in three-component interaction with benzaldehydes and active methylene nitriles
GV Grygoriv, DA Lega, VP Chernykh, L Zaprutko, AK Gzella, A Pawełczyk, ...
RSC advances 8 (65), 37295-37302, 2018
82018
The synthesis, anti-inflammatory, analgesic and antimicrobial activities of ethyl 2-amino-4-alkyl-4, 6-dihydropyrano [3, 2c][2, 1] benzothiazin-3-carboxylate 5, 5-dioxides and …
DA Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ...
Journal of Organic and Pharmaceutical Chemistry 14 (4 (56)), 3-11, 2016
62016
Synthesis of novel spiro-condensed 2-amino-4H-pyrans based on 1, 2-benzoxathiin-4 (3H)-one 2, 2-dioxide
GV Grygoriv, DA Lega, L Zaprutko, AK Gzella, E Wieczorek-Dziurla, ...
Chemistry of Heterocyclic Compounds 55 (3), 254-260, 2019
52019
Antimicrobial, anti-inflammatory and analgesic activities of 2-amino-6-ethyl-4, 6-dihydropyrano| 3, 2-c|| 2, 1| benzothiazine 5, 5-dioxides and triethylammonium 3-| 1-(4 …
DO Lega, NI Filimonova, IA Zupanets, SK Shebeko, VP Chernykh, ...
Вісник фармації, 61-69, 2016
42016
Synthesis of 1, 2-benzoxathiine 2, 2-dioxide derivatives using aliphatic aldehydes and assessment of their antimicrobial activity
GV Grygoriv, DO Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
32017
The use of aliphatic aldehydes in the synthesis of new pyran annulated derivatives of 1h-2, 1-benzothiazin-4-one 2, 2-dioxide via domino-type interactions. The antimicrobial …
DA Lega, NI Filimonova, OG Geyderikh, VP Chernykh, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 14 (2 (54)), 29-40, 2016
32016
Domino-reactions of 1, 2-benzoxathiin-4 (3H)-one 2, 2-dioxide, hetarenecarbaldehydes and active methylene nitriles in the construction of new 2-amino-4H-pyrans and the study of …
GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
22018
Spiro [benzo [е] pyrano [3, 2-c][1, 2] oxathiin-4, 3’-indolil]-3-carbonitrile 5, 5-dioxides: synthesis and the biological activity study
GV Grygoriv, DA Lega, IA Zupanets, SK Shebeko, SM Zimin, ...
12019
The synthesis of 2-amino-4-aryl-4H-pyrano [3, 2-c][1, 2] benzoxathiine-3-carbonitrile 5, 5-dioxides and the study of their effect on the blood coagulation process
GV Grygoriv, DA Lega, LM Shemchuk, LM Maloshtan, GS Kalenichenko, ...
News of Pharmacy, 3-8, 2018
12018
Cycloalkanecarbaldehydes in synthesis of novel 1, 2-benzoxathiin-4 (3H)-on 2, 2-dioxide derivatives and study of the antimicrobial activity of synthesized compounds
GV Grygoriv, DA Lega, VP Chernykh, TP Osolodchenko, LA Shemchuk
12017
In vitro antimicrobial activity evaluation of 2-amino-3-r-6-ethyl-4, 6-dihydropyrano [3, 2-c][2, 1] benzothiazine 5, 5-dioxides with 4-aryl substituent and spirofused with 2 …
DA Lega, NI Filimonova, HM Dikaya, VP Chernykh, LA Shemchuk
Ukrainian biopharmaceutical journal, 24-32, 2016
12016
Possible outcomes of 4-chloro-1-ethyl-1H-benzo [C][1, 2] thiazine-3-carbaldehyde 2, 2-dioxide interaction with 1, 2-dihydro-3H-pyrazol-3-ones
TI Kolodyazhna, DA Lega, LA Shemchuk
2022
Some Aspects of 4H‐Pyrans Synthesis Based on 4‐Chloro‐1‐ethyl‐1H‐benzo[c][1,2]thiazine‐3‐carbaldehyde 2,2‐dioxide: Antimicrobial Activity of the …
TI Kolodyazhna, DA Lega, SY Suikov, AA Kyrylchuk, MV Vovk, ...
ChemistrySelect 6 (48), 14005-14012, 2021
2021
1, 2-Benzoxathiin-4 (3H)-one 2, 2-dioxide–an underinvestigated building block with a high synthetic and pharmacological potential: synthesis, chemical properties, biological …
HV Hryhoriv, DA Lega, LA Shemchuk
Journal of Organic and Pharmaceutical Chemistry 19 (2 (74)), 4-28, 2021
2021
2-Amino-4-(4-chloro-1-ethyl-2, 2-dioxo-1H-benzo [c][1, 2] thiazin-3-yl)-7, 7-dimethyl-5-oxo-5, 6, 7, 8-tetrahydro-4H-chromene-3-carbonitrile: single-crystal X-ray diffraction …
MO Shyshkina, DA Lega, VD Goryachiy, LM Shemchuk, DV Levashov, ...
Acta Crystallographica Section E: Crystallographic Communications 77 (3 …, 2021
2021
1, 2-Benzoxathiin-4 (3H)-one 2, 2-dioxide hydrazones: synthesis and antimicrobial activity
D Lega, H Hryhoriv, A Gzella, L Shemchuk
2021
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