ClC‐7 is a slowly voltage‐gated 2Cl−/1H+‐exchanger and requires Ostm1 for transport activity L Leisle, CF Ludwig, FA Wagner, TJ Jentsch, T Stauber The EMBO Journal 30 (11), 2140-2152, 2011 | 227 | 2011 |
Incorporation of non-canonical amino acids L Leisle, F Valiyaveetil, RA Mehl, CA Ahern Novel Chemical Tools to Study Ion Channel Biology, 119-151, 2015 | 47 | 2015 |
Recurrent Stroke Due to a Novel Voltage Sensor Mutation in Cav2.1 Responds to Verapamil E Knierim, L Leisle, C Wagner, B Weschke, B Lucke, G Bohner, JP Dreier, ... Stroke 42 (2), e14-e17, 2011 | 47 | 2011 |
Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl−/1H+ exchanger ClC-7/Ostm1 CF Ludwig, F Ullrich, L Leisle, T Stauber, TJ Jentsch Journal of Biological Chemistry 288 (40), 28611-28619, 2013 | 42 | 2013 |
Atomic determinants of BK channel activation by polyunsaturated fatty acids Y Tian, M Aursnes, TV Hansen, JE Tungen, JD Galpin, L Leisle, CA Ahern, ... Proceedings of the National Academy of Sciences 113 (48), 13905-13910, 2016 | 38 | 2016 |
Angiotensin-converting enzyme as a GPIase: a critical reevaluation L Leisle, ET Parkin, AJ Turner, NM Hooper Nature medicine 11 (11), 1139-1140, 2005 | 38 | 2005 |
Differential effects of N-glycans on surface expression suggest structural differences between the acid-sensing ion channel (ASIC) 1a and ASIC1b I Kadurin, A Golubovic, L Leisle, H Schindelin, S Gründer Biochemical Journal 412 (3), 469-475, 2008 | 33 | 2008 |
Analysis of CLCN2 as Candidate Gene for Megalencephalic Leukoencephalopathy with Subcortical Cysts GC Scheper, CGM van Berkel, L Leisle, KE de Groot, A Errami, TJ Jentsch, ... Genetic testing and molecular biomarkers 14 (2), 255-257, 2010 | 30 | 2010 |
Cellular encoding of Cy dyes for single-molecule imaging L Leisle, R Chadda, JD Lueck, DT Infield, JD Galpin, V Krishnamani, ... Elife 5, e19088, 2016 | 27 | 2016 |
Probing the conformation of a conserved glutamic acid within the Cl− pathway of a CLC H+/Cl− exchanger M Vien, D Basilio, L Leisle, A Accardi Journal of General Physiology 149 (4), 523-529, 2017 | 21 | 2017 |
Divergent Cl- and H+ pathways underlie transport coupling and gating in CLC exchangers and channels L Leisle, Y Xu, E Fortea, S Lee, JD Galpin, M Vien, CA Ahern, A Accardi, ... Elife 9, e51224, 2020 | 17 | 2020 |
SUPPLEMENTARY INFORMATION TO L Leisle, CF Ludwig, FA Wagner, TJ Jentsch, T Stauber | 16 | 2022 |
Cross-kingdom auxiliary subunit modulation of a voltage-gated sodium channel S Molinarolo, S Lee, L Leisle, JD Lueck, D Granata, V Carnevale, ... Journal of Biological Chemistry 293 (14), 4981-4992, 2018 | 10 | 2018 |
Dynorphin neuropeptides decrease apparent proton affinity of ASIC1a by occluding the acidic pocket L Leisle, M Margreiter, A Ortega-Ramírez, E Cleuvers, M Bachmann, ... Journal of medicinal chemistry 64 (18), 13299-13311, 2021 | 8 | 2021 |
Backbone amides are determinants of Cl− selectivity in CLC ion channels L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, JD Galpin, ... Nature communications 13 (1), 7508, 2022 | 2 | 2022 |
Efficient expression of a cnidarian peptide-gated ion channel in mammalian cells M Bachmann, A Ortega-Ramírez, L Leisle, S Gründer Channels 15 (1), 273-283, 2021 | 2 | 2021 |
Backbone amides are key determinants of Cl− selectivity in CLC ion channels L Leisle, K Lam, S Dehghani-Ghahnaviyeh, E Fortea, J Galpin, CA Ahern, ... bioRxiv, 2022.07. 01.498497, 2022 | | 2022 |
Mapping the binding site of the opioid neuropeptide Big Dynorphin on ASIC1a L Leisle, MA Margreiter, G Rossetti, S Gruender ACTA PHYSIOLOGICA 227, 2019 | | 2019 |
Backbone Amide Nitrogen Atoms are Key Determinants of Inter-Anion Discrimination in CLCs L Leisle, E Fortea, J Galpin, C Ahern, A Accardi Biophysical Journal 114 (3), 493a, 2018 | | 2018 |
Genetically Encoding Single-Molecule Fluorophores into Ion Channels in Living Cells L Leisle, R Chadda, JD Galpin, JL Robertson, CA Ahern Biophysical journal 110 (3), 34a, 2016 | | 2016 |