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David Habiel
David Habiel
Principal Scientist, Type II Immunity and Fibrosis, I&I, Sanofi
Підтверджена електронна адреса в sanofi.com - Домашня сторінка
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Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism
S Parathath, SL Mick, JE Feig, V Joaquin, L Grauer, DM Habiel, ...
Circulation research 109 (10), 1141-1152, 2011
1822011
Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo
MS Hohmann, DM Habiel, AL Coelho, WA Verri Jr, CM Hogaboam
American journal of respiratory cell and molecular biology 60 (1), 28-40, 2019
1562019
Innate immunity of the lung: from basic mechanisms to translational medicine
D Hartl, R Tirouvanziam, J Laval, CM Greene, D Habiel, L Sharma, ...
Journal of innate immunity 10 (5-6), 487-501, 2018
1372018
Inhibitor of NF-κB kinases α and β are both essential for high mobility group box 1-mediated chemotaxis
M Penzo, R Molteni, T Suda, S Samaniego, A Raucci, DM Habiel, F Miller, ...
The Journal of Immunology 184 (8), 4497-4509, 2010
1302010
Inhibitor of NF-κB kinases α and β are both essential for high mobility group box 1-mediated chemotaxis
M Penzo, R Molteni, T Suda, S Samaniego, A Raucci, DM Habiel, F Miller, ...
The Journal of Immunology 184 (8), 4497-4509, 2010
1302010
PD-L1 on invasive fibroblasts drives fibrosis in a humanized model of idiopathic pulmonary fibrosis
Y Geng, X Liu, J Liang, DM Habiel, V Kulur, AL Coelho, N Deng, T Xie, ...
Jci Insight 4 (6), 2019
1002019
The IKKα-dependent NF-κB p52/RelB noncanonical pathway is essential to sustain a CXCL12 autocrine loop in cells migrating in response to HMGB1
RR Kew, M Penzo, DM Habiel, KB Marcu
The Journal of Immunology 188 (5), 2380-2386, 2012
882012
Heterogeneity of fibroblasts and myofibroblasts in pulmonary fibrosis
DM Habiel, CM Hogaboam
Current pathobiology reports 5, 101-110, 2017
872017
The Hsp110 molecular chaperone stabilizes apolipoprotein B from endoplasmic reticulum-associated degradation (ERAD)
SL Hrizo, V Gusarova, DM Habiel, JL Goeckeler, EA Fisher, JL Brodsky
Journal of biological chemistry 282 (45), 32665-32675, 2007
862007
Targeting of TAM receptors ameliorates fibrotic mechanisms in idiopathic pulmonary fibrosis
MS Espindola, DM Habiel, R Narayanan, I Jones, AL Coelho, LA Murray, ...
American journal of respiratory and critical care medicine 197 (11), 1443-1456, 2018
822018
Heterogeneity in fibroblast proliferation and survival in idiopathic pulmonary fibrosis
DM Habiel, C Hogaboam
Frontiers in pharmacology 5, 75001, 2014
712014
Syndecan-1 promotes lung fibrosis by regulating epithelial reprogramming through extracellular vesicles
T Parimon, C Yao, DM Habiel, L Ge, SA Bora, R Brauer, CM Evans, T Xie, ...
JCI insight 4 (17), 2019
682019
Antifibrotic role of vascular endothelial growth factor in pulmonary fibrosis
LA Murray, DM Habiel, M Hohmann, A Camelo, H Shang, Y Zhou, ...
JCI insight 2 (16), 2017
672017
Axl receptor blockade ameliorates pulmonary pathology resulting from primary viral infection and viral exacerbation of asthma
T Shibata, DM Habiel, AL Coelho, SL Kunkel, NW Lukacs, CM Hogaboam
The Journal of Immunology 192 (8), 3569-3581, 2014
632014
Neutrophil recruitment to the lung in both C5a-and CXCL1-induced alveolitis is impaired in vitamin D–binding protein–deficient mice
G Trujillo, DM Habiel, L Ge, M Ramadass, NE Cooke, RR Kew
The Journal of Immunology 191 (2), 848-856, 2013
592013
Anti-fibrotic effects of CXCR4-targeting i-body AD-114 in preclinical models of pulmonary fibrosis
K Griffiths, DM Habiel, J Jaffar, U Binder, WG Darby, CG Hosking, ...
Scientific reports 8 (1), 3212, 2018
512018
Identification of two distinct cell binding sequences in the vitamin D binding protein
J Zhang, DM Habiel, M Ramadass, RR Kew
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803 (5), 623-629, 2010
502010
miR-323a-3p regulates lung fibrosis by targeting multiple profibrotic pathways
L Ge, DM Habiel, PM Hansbro, RY Kim, SA Gharib, JD Edelman, ...
JCI insight 1 (20), 2016
482016
Toll like receptor 3 plays a critical role in the progression and severity of acetaminophen-induced hepatotoxicity
KA Cavassani, AP Moreira, D Habiel, T Ito, AL Coelho, RM Allen, B Hu, ...
PLoS One 8 (6), e65899, 2013
482013
Syndecan-1 controls lung tumorigenesis by regulating miRNAs packaged in exosomes
T Parimon, R Brauer, SY Schlesinger, T Xie, D Jiang, L Ge, Y Huang, ...
The American journal of pathology 188 (4), 1094-1103, 2018
462018
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