Mitochondrial dysfunction during brain aging: role of oxidative stress and modulation by antioxidant supplementation S Chakrabarti, S Munshi, K Banerjee, IG Thakurta, M Sinha, MB Bagh Aging and disease 2 (3), 242, 2011 | 158 | 2011 |
Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth … E Kong, S Peng, G Chandra, C Sarkar, Z Zhang, MB Bagh, AB Mukherjee Journal of Biological Chemistry 288 (13), 9112-9125, 2013 | 153 | 2013 |
Misrouting of v-ATPase subunit V0a1 dysregulates lysosomal acidification in a neurodegenerative lysosomal storage disease model MB Bagh, S Peng, G Chandra, Z Zhang, SP Singh, N Pattabiraman, A Liu, ... Nature communications 8 (1), 14612, 2017 | 134 | 2017 |
Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses AB Mukherjee, AP Appu, T Sadhukhan, S Casey, A Mondal, Z Zhang, ... Molecular neurodegeneration 14, 1-23, 2019 | 85 | 2019 |
Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in … MB Bagh, AK Maiti, S Jana, K Banerjee, A Roy, S Chakrabarti Free radical research 42 (6), 574-581, 2008 | 50 | 2008 |
Dopamine but not 3, 4-dihydroxy phenylacetic acid (DOPAC) inhibits brain respiratory chain activity by autoxidation and mitochondria catalyzed oxidation to quinone products … S Jana, AK Maiti, MB Bagh, K Banerjee, A Das, A Roy, S Chakrabarti Brain Research 1139, 195-200, 2007 | 47 | 2007 |
Age-related oxidative decline of mitochondrial functions in rat brain is prevented by long term oral antioxidant supplementation MB Bagh, IG Thakurta, M Biswas, P Behera, S Chakrabarti Biogerontology 12, 119-131, 2011 | 43 | 2011 |
Combination of N-acetylcysteine, α-lipoic acid and α-tocopherol substantially prevents the brain synaptosomal alterations and memory and learning deficits of aged rats IG Thakurta, P Banerjee, MB Bagh, A Ghosh, A Sahoo, S Chattopadhyay, ... Experimental gerontology 50, 19-25, 2014 | 35 | 2014 |
Cln1 gene disruption in mice reveals a common pathogenic link between two of the most lethal childhood neurodegenerative lysosomal storage disorders G Chandra, MB Bagh, S Peng, A Saha, C Sarkar, M Moralle, Z Zhang, ... Human molecular genetics 24 (19), 5416-5432, 2015 | 31 | 2015 |
Cln3‐mutations underlying juvenile neuronal ceroid lipofuscinosis cause significantly reduced levels of Palmitoyl‐protein thioesterases‐1 (Ppt1)‐protein and Ppt1 … AP Appu, MB Bagh, T Sadhukhan, A Mondal, S Casey, AB Mukherjee Journal of Inherited Metabolic Disease 42 (5), 944-954, 2019 | 21 | 2019 |
Dietary supplementation with N-acetylcysteine, α-tocopherol and α-lipoic acid prevents age related decline in Na+,K+-ATPase activity and associated … MB Bagh, AK Maiti, A Roy, S Chakrabarti Biogerontology 9, 421-428, 2008 | 21 | 2008 |
Cln1‐mutations suppress Rab7‐RILP interaction and impair autophagy contributing to neuropathology in a mouse model of infantile neuronal ceroid lipofuscinosis C Sarkar, T Sadhukhan, MB Bagh, AP Appu, G Chandra, A Mondal, ... Journal of inherited metabolic disease 43 (5), 1082-1101, 2020 | 18 | 2020 |
Suppression of agrin‐22 production and synaptic dysfunction in Cln1−/− mice S Peng, J Xu, KA Pelkey, G Chandra, Z Zhang, MB Bagh, X Yuan, LG Wu, ... Annals of clinical and translational neurology 2 (12), 1085-1104, 2015 | 16 | 2015 |
In a mouse model of INCL reduced S‐palmitoylation of cytosolic thioesterase APT1 contributes to microglia proliferation and neuroinflammation T Sadhukhan, MB Bagh, AP Appu, A Mondal, W Zhang, A Liu, ... Journal of Inherited Metabolic Disease 44 (4), 1051-1069, 2021 | 15 | 2021 |
Ppt1‐deficiency dysregulates lysosomal Ca++ homeostasis contributing to pathogenesis in a mouse model of CLN1 disease A Mondal, AP Appu, T Sadhukhan, MB Bagh, RM Previde, S Sadhukhan, ... Journal of inherited metabolic disease 45 (3), 635-656, 2022 | 6 | 2022 |
A lysosomal targeting defect of V0a1 suppresses V‐ATPase activity elevating lysosomal pH in Ppt1‐/‐ mice: amelioration by NtBuHA M Bagh, G Chandra, S Peng, Z Zhang, A Mukherjee The FASEB Journal 29, 570.6, 2015 | 3 | 2015 |
Ablation of microRNA-155 and neuroinflammation in a mouse model of CLN1-disease T Sadhukhan, MB Bagh, S Sadhukhan, AP Appu, A Mondal, J Iben, T Li, ... Biochemical and Biophysical Research Communications 571, 137-144, 2021 | 1 | 2021 |
Dysregulation of V‐ATPase Function Impairs Lysosomal Acidification in a Mouse Model of a Rare Lysosomal Storage Disease, INCL MB Bagh, S Peng, G Chandra, Z Zhang, AB Mukherjee The FASEB Journal 30, 879.1-879.1, 2016 | 1 | 2016 |
Disruption of lysosomal nutrient sensing scaffold contributes to pathogenesis of a fatal neurodegenerative lysosomal storage disease MB Bagh, AP Appu, T Sadhukhan, A Mondal, N Plavelil, M Raghavankutty, ... Journal of Biological Chemistry 300 (2), 2024 | | 2024 |
Disruption of lysosomal nutrient sensing scaffold hyperactivates mTORC1 contributing to pathogenesis of a fatal neurodegenerative disease. MB Bagh, AP Appu, T Sadhukhan, A Mondal, N Plavelil, M Raghavankutty, ... The Journal of Biological Chemistry, 105641-105641, 2024 | | 2024 |