Підписатись
Avinashnarayan Venkatanarayan
Avinashnarayan Venkatanarayan
Research Investigator II, Bristol-Myers and Squibb
Підтверджена електронна адреса в bms.com - Домашня сторінка
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IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo
A Venkatanarayan, P Raulji, W Norton, D Chakravarti, C Coarfa, X Su, ...
Nature 517 (7536), 626-630, 2015
1322015
Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma
MM Singh, B Johnson, A Venkatarayan, ER Flores, J Zhang, X Su, ...
Neuro-oncology 17 (11), 1463-1473, 2015
822015
Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8
D Chakravarti, X Su, MS Cho, NHB Bui, C Coarfa, A Venkatanarayan, ...
Proceedings of the National Academy of Sciences 111 (5), E572-E581, 2014
792014
ARAF mutations confer resistance to the RAF inhibitor belvarafenib in melanoma
I Yen, F Shanahan, J Lee, YS Hong, SJ Shin, AR Moore, J Sudhamsu, ...
Nature 594 (7863), 418-423, 2021
762021
Pharmacological induction of RAS-GTP confers RAF inhibitor sensitivity in KRAS mutant tumors
I Yen, F Shanahan, M Merchant, C Orr, T Hunsaker, M Durk, H La, ...
Cancer Cell 34 (4), 611-625. e7, 2018
742018
Copy number gain of hsa-miR-569 at 3q26. 2 leads to loss of TP53INP1 and aggressiveness of epithelial cancers
P Chaluvally-Raghavan, F Zhang, S Pradeep, MP Hamilton, X Zhao, ...
Cancer Cell 26 (6), 863-879, 2014
532014
Noxa couples lysosomal membrane permeabilization and apoptosis during oxidative stress
CO Eno, G Zhao, A Venkatanarayan, B Wang, ER Flores, C Li
Free radical Biology and Medicine 65, 26-37, 2013
512013
TAp63 suppresses mammary tumorigenesis through regulation of the Hippo pathway
X Su, M Napoli, HA Abbas, A Venkatanarayan, NHB Bui, C Coarfa, YJ Gi, ...
Oncogene 36 (17), 2377-2393, 2017
422017
ΔNp63/DGCR8-dependent microRNAs mediate therapeutic efficacy of HDAC inhibitors in cancer
M Napoli, A Venkatanarayan, P Raulji, BA Meyers, W Norton, LS Mangala, ...
Cancer cell 29 (6), 874-888, 2016
412016
Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73
A Venkatanarayan, P Raulji, W Norton, ER Flores
Cell Cycle 15 (2), 164-171, 2016
372016
Dimerization induced by C-terminal 14–3–3 binding is sufficient for BRAF kinase activation
NPD Liau, A Venkatanarayan, JG Quinn, W Phung, S Malek, ...
Biochemistry 59 (41), 3982-3992, 2020
322020
CRAF dimerization with ARAF regulates KRAS-driven tumor growth
A Venkatanarayan, J Liang, I Yen, F Shanahan, B Haley, L Phu, ...
Cell reports 38 (6), 2022
202022
Activating p53 family member TAp63: a novel therapeutic strategy for targeting p53‐altered tumors
PH Gunaratne, Y Pan, AK Rao, C Lin, A Hernandez‐Herrera, K Liang, ...
Cancer 125 (14), 2409-2422, 2019
202019
NRG1 is a critical regulator of differentiation in TP63-driven squamous cell carcinoma
GV Hegde, C de la Cruz, JM Giltnane, L Crocker, A Venkatanarayan, ...
Elife 8, e46551, 2019
102019
ARID1A mutations confer intrinsic and acquired resistance to cetuximab treatment in colorectal cancer
RM Johnson, X Qu, CF Lin, LY Huw, A Venkatanarayan, E Sokol, FS Ou, ...
Nature communications 13 (1), 5478, 2022
92022
Zfh-2 facilitates Notch-induced apoptosis in the CNS and appendages of Drosophila melanogaster
AR Guntur, A Venkatanarayan, S Gangula, MJ Lundell
Developmental Biology 475, 65-79, 2021
82021
Hunchback prevents notch-induced apoptosis in the serotonergic lineage of Drosophila Melanogaster
E Pérez, A Venkatanarayan, MJ Lundell
Developmental biology 486, 109-120, 2022
42022
Partners in Crime: Clandestine Operations among RAS-RAF Accomplices in Promoting Tumorigenesis
A Venkatanarayan, S Malek
Molecular cell 76 (6), 853-855, 2019
12019
CRAF-mediated inactivation of epigenetic repressor complexes promotes KRAS-driven tumorigenesis.
A Venkatanarayan, C Klijn, S Malek
MOLECULAR CANCER RESEARCH 18 (5), 60-60, 2020
2020
Abstract B14: CRAF-mediated inactivation of epigenetic repressor complexes promotes KRAS-driven tumorigenesis
A Venkatanarayan, C Klijn, S Malek
Molecular Cancer Research 18 (5_Supplement), B14-B14, 2020
2020
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