Підписатись
Shunqi Yan, Ph.D.
Shunqi Yan, Ph.D.
Arthrosi Therapeutics, Inc.
Підтверджена електронна адреса в arthrosi.com
Назва
Посилання
Посилання
Рік
Targeted inhibition of mutant IDH2 in leukemia cells induces cellular differentiation
F Wang, J Travins, B DeLaBarre, V Penard-Lacronique, S Schalm, ...
Science 340 (6132), 622-626, 2013
9312013
Structural identification of two metabolites of catechins and their kinetics in human urine and blood after tea ingestion
C Li, MJ Lee, S Sheng, X Meng, S Prabhu, B Winnik, B Huang, JY Chung, ...
Chemical research in toxicology 13 (3), 177-184, 2000
3592000
Acquired resistance to the TRK inhibitor entrectinib in colorectal cancer
M Russo, S Misale, G Wei, G Siravegna, G Crisafulli, L Lazzari, G Corti, ...
Cancer discovery 6 (1), 36-44, 2016
2942016
Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo
J Popovici-Muller, JO Saunders, FG Salituro, JM Travins, S Yan, F Zhao, ...
ACS Medicinal Chemistry Letters 3 (10), 850-855, 2012
2392012
Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents
J Zhu, X Song, HP Lin, DC Young, S Yan, VE Marquez, CS Chen
Journal of the National Cancer Institute 94 (23), 1745-1757, 2002
2152002
Identification and structure–activity relationships of substituted pyridones as inhibitors of Pim-1 kinase
IW Cheney, S Yan, T Appleby, H Walker, T Vo, N Yao, R Hamatake, ...
Bioorganic & medicinal chemistry letters 17 (6), 1679-1683, 2007
2022007
Small molecule activation of PKM2 in cancer cells induces serine auxotrophy
C Kung, J Hixon, S Choe, K Marks, S Gross, E Murphy, B DeLaBarre, ...
Chemistry & biology 19 (9), 1187-1198, 2012
1922012
Structure–activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors
F Rong, S Chow, S Yan, G Larson, Z Hong, J Wu
Bioorganic & Medicinal Chemistry Letters 17 (6), 1663-1666, 2007
1362007
Isothiazoles as active-site inhibitors of HCV NS5B polymerase
S Yan, T Appleby, E Gunic, JH Shim, T Tasu, H Kim, F Rong, H Chen, ...
Bioorganic & Medicinal Chemistry Letters 17 (1), 28-33, 2007
792007
Novel thiazolones as HCV NS5B polymerase allosteric inhibitors: Further designs, SAR, and X-ray complex structure
S Yan, G Larson, JZ Wu, T Appleby, Y Ding, R Hamatake, Z Hong, N Yao
Bioorganic & Medicinal Chemistry Letters 17 (1), 63-67, 2007
792007
Piperazine compounds as pyruvate kinase M2 modulators and their preparation, compositions and use in the treatment of cancer
FG Salituro, JO Saunders, S Yan
US Patent 8,889,667, 2014
75*2014
Therapeutically active compounds and their methods of use
G Cianchetta, B Delabarre, J Popovici-Muller, FG Salituro, JO Saunders, ...
US Patent 9,732,062, 2017
732017
Preparation of purinone compounds as kinase inhibitors
S Yan, L Wang, LL Frye, W Chen, DJ Loury
US Patent 8,501,724, 2013
73*2013
Compounds, their pharmaceutical compositions and their uses as IDH1 mutants inhibitors for treating cancers
S Cao, J Popovici-Muller, FG Salituro, J Saunders, X Tan, J Travins, ...
732012
Thiazolone-acylsulfonamides as novel HCV NS5B polymerase allosteric inhibitors: convergence of structure-based drug design and X-ray crystallographic study
S Yan, T Appleby, G Larson, JZ Wu, RK Hamatake, Z Hong, N Yao
Bioorganic & medicinal chemistry letters 17 (7), 1991-1995, 2007
722007
Structure-based design of a novel thiazolone scaffold as HCV NS5B polymerase allosteric inhibitors
S Yan, T Appleby, G Larson, JZ Wu, R Hamatake, Z Hong, N Yao
Bioorganic & medicinal chemistry letters 16 (22), 5888-5891, 2006
702006
Modulation of Carbenic Reactivity by π-Complexation to Aromatics
RA Moss, S Yan, K Krogh-Jespersen
Journal of the American Chemical Society 120 (5), 1088-1089, 1998
541998
Ab Initio Electronic Structure Calculations on Chlorocarbene− Ethylene and Chlorocarbene− Benzene Complexes
K Krogh-Jespersen, S Yan, RA Moss
Journal of the American Chemical Society 121 (26), 6269-6274, 1999
511999
Preparation of purinone compounds as kinase inhibitors
S Yan, L Wang, LL Frye, W Chen, DJ Loury
US Patent 9,469,642, 2016
48*2016
Therapeutically active compositions and their methods of use
J Popovici-Muller, FG Salituro, J Saunders, J Travins, S Yan
US Patent App. 13/810,410, 2013
482013
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