| Recent advances in the discovery of small-molecule inhibitors of HIV-1 integrase E Choi, JR Mallareddy, D Lu, S Kolluru Future Science OA 4 (9), FSO338, 2018 | 43 | 2018 |
| Aminopyrazole based CDK9 PROTAC sensitizes pancreatic cancer cells to venetoclax HM King, S Rana, SP Kubica, JR Mallareddy, S Kizhake, EL Ezell, ... Bioorganic & medicinal chemistry letters 43, 128061, 2021 | 37 | 2021 |
| Design, synthesis, pharmacological evaluation, and structure− activity study of novel endomorphin analogues with multiple structural modifications JR Mallareddy, A Borics, A Keresztes, KE Kövér, D Tourwé, G Tóth Journal of Medicinal Chemistry 54 (5), 1462-1472, 2011 | 37 | 2011 |
| Identification of potential binding pocket on viral oncoprotein HPV16 E6: a promising anti-cancer target for small molecule drug discovery S Kolluru, R Momoh, L Lin, JR Mallareddy, JL Krstenansky BMC Molecular and Cell Biology 20 (1), 1-11, 2019 | 25 | 2019 |
| Synthesis and pharmacological evaluation of [3H] HS665, a novel, highly selective radioligand for the kappa opioid receptor E Guerrieri, JR Mallareddy, G Tóth, H Schmidhammer, M Spetea ACS Chemical Neuroscience 6 (3), 456-463, 2015 | 24 | 2015 |
| Inhibitors, PROTACs and molecular glues as diverse therapeutic modalities to target cyclin-dependent kinase S Rana, JR Mallareddy, S Singh, L Boghean, A Natarajan Cancers 13 (21), 5506, 2021 | 23 | 2021 |
| [3H] IVDE77, a novel radioligand with high affinity and selectivity for the insulin-regulated aminopeptidase A Nikolaou, I Van Den Eynde, D Tourwé, G Vauquelin, G Tóth, ... European Journal of Pharmacology 702 (1-3), 93-102, 2013 | 23 | 2013 |
| The effect of Pro2 modifications on the structural and pharmacological properties of endomorphin-2 A Borics, JR Mallareddy, I Timári, KE Kövér, A Keresztes, G Tóth Journal of Medicinal Chemistry 55 (19), 8418-8428, 2012 | 18 | 2012 |
| Synthesis and pharmacological characterization of ethylenediamine synthetic opioids in human μ‐opiate receptor 1 (OPRM1) expressing cells T Hsu, JR Mallareddy, K Yoshida, V Bustamante, T Lee, JL Krstenansky, ... Pharmacology Research & Perspectives 7 (5), e00511, 2019 | 15 | 2019 |
| Effects of synthetic analogues of human opiorphin on rat brain opioid receptors Z Benyhe, G Toth, M Wollemann, A Borsodi, Z Helyes, C Rougeot, ... Journal of Physiology and Pharmacology 65, 525-530, 2014 | 12 | 2014 |
| Transport Characteristics of Endomorphin‐2 Analogues in Brain Capillary Endothelial Cells JR Mallareddy, G Tóth, C Fazakas, J Molnár, P Nagyőszi, AW Lipkowski, ... Chemical Biology & Drug Design 79 (4), 507-513, 2012 | 12 | 2012 |
| Radiotracers, tritium labelling of neuropeptides G Tóth, JR Mallareddy, F Tóth, AW Lipkowski, D Tourwé Arkivoc 2012 (v) 163-174, 2012 | 12 | 2012 |
| Tritiated opioid receptor ligands as radiotracers G Toth, J Reddy Mallareddy Current Pharmaceutical Design 19 (42), 7461-7472, 2013 | 10 | 2013 |
| Asymmetric Synthesis and Conformational Analysis by NMR Spectroscopy and MD of Aba‐and α‐MeAba‐Containing Dermorphin Analogues B Vandormael, R De Wachter, JC Martins, PMS Hendrickx, A Keresztes, ... ChemMedChem 6 (11), 2035-2047, 2011 | 9 | 2011 |
| Structure activity relationship (SAR) study identifies a quinoxaline urea analog that modulates IKKβ phosphorylation for pancreatic cancer therapy S Sagar#, S Singh#, JR Mallareddy#, YA Sonawane#, ... European Journal of Medicinal Chemistry, 113579, 2021 | 8 | 2021 |
| Stereoselective analysis of endomorphin diastereomers: Resolution of biologically active analogues by capillary electrophoresis applying cyclodextrins as mobile phase additives K Németh, JR Mallareddy, C Domonkos, J Visy, G Tóth, A Péter Journal of Pharmaceutical and Biomedical Analysis 70, 32-39, 2012 | 8 | 2012 |
| Systemic administration of a brain permeable Cdk5 inhibitor alters neurobehavior A Umfress, S Singh, KJ Ryan, A Chakraborti, F Plattner, Y Sonawane, ... Frontiers in pharmacology 13, 863762, 2022 | 7 | 2022 |
| Characterization of antinociceptive potency of endomorphin-2 derivatives with unnatural amino acids in rats G Kovács, Z Petrovszki, J Mallareddy, G Tóth, G Benedek, G Horváth Acta Physiologica Hungarica 99 (3), 353-363, 2012 | 7 | 2012 |
| Small-molecule IKKβ activation modulator (IKAM) targets MAP3K1 and inhibits pancreatic tumor growth JV Napoleon, S Sagar, SP Kubica, L Boghean, S Kour, HM King, ... Proceedings of the National Academy of Sciences 119 (18), e2115071119, 2022 | 6 | 2022 |
| Selective CDK9 degradation using a proteolysis-targeting chimera (PROTAC) strategy JR Mallareddy, S Singh, L Boghean, A Natarajan Future Medicinal Chemistry 14 (3), 131-134, 2022 | 6 | 2022 |
