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Patrick Hwu
Patrick Hwu
President and CEO, The Moffitt Cancer Center, Tampa, FL
Подтвержден адрес электронной почты в домене moffitt.org
Название
Процитировано
Процитировано
Год
Safety and activity of anti–PD-L1 antibody in patients with advanced cancer
JR Brahmer, SS Tykodi, LQM Chow, WJ Hwu, SL Topalian, P Hwu, ...
New England Journal of Medicine 366 (26), 2455-2465, 2012
86982012
Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
V Gopalakrishnan, CN Spencer, L Nezi, A Reuben, MC Andrews, ...
Science 359 (6371), 97-103, 2018
37812018
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytes
ME Dudley, JR Wunderlich, PF Robbins, JC Yang, P Hwu, ...
Science 298 (5594), 850-854, 2002
37212002
A randomized trial of bevacizumab, an anti–vascular endothelial growth factor antibody, for metastatic renal cancer
JC Yang, L Haworth, RM Sherry, P Hwu, DJ Schwartzentruber, ...
New England Journal of Medicine 349 (5), 427-434, 2003
35572003
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
SA Rosenberg, JC Yang, DJ Schwartzentruber, P Hwu, FM Marincola, ...
Nature medicine 4 (3), 321-327, 1998
22321998
Chimeric antigen receptor T-cell therapy—assessment and management of toxicities
SS Neelapu, S Tummala, P Kebriaei, W Wierda, C Gutierrez, FL Locke, ...
Nature reviews Clinical oncology 15 (1), 47-62, 2018
20232018
Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
GQ Phan, JC Yang, RM Sherry, P Hwu, SL Topalian, ...
Proceedings of the National Academy of Sciences 100 (14), 8372-8377, 2003
19272003
B cells and tertiary lymphoid structures promote immunotherapy response
BA Helmink, SM Reddy, J Gao, S Zhang, R Basar, R Thakur, K Yizhak, ...
Nature 577 (7791), 549-555, 2020
16312020
A phase I study on adoptive immunotherapy using gene-modified T cells for ovarian cancer
MH Kershaw, JA Westwood, LL Parker, G Wang, Z Eshhar, ...
Clinical cancer research 12 (20), 6106-6115, 2006
14432006
Loss of PTEN promotes resistance to T cell–mediated immunotherapy
W Peng, JQ Chen, C Liu, S Malu, C Creasy, MT Tetzlaff, C Xu, ...
Cancer discovery 6 (2), 202-216, 2016
13622016
PD-L1 expression in triple-negative breast cancer
EA Mittendorf, AV Philips, F Meric-Bernstam, N Qiao, Y Wu, S Harrington, ...
Cancer immunology research 2 (4), 361-370, 2014
12892014
Loss of IFN-γ pathway genes in tumor cells as a mechanism of resistance to anti-CTLA-4 therapy
J Gao, LZ Shi, H Zhao, J Chen, L Xiong, Q He, T Chen, J Roszik, ...
Cell 167 (2), 397-404. e9, 2016
11812016
gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
DJ Schwartzentruber, DH Lawson, JM Richards, RM Conry, DM Miller, ...
New England Journal of Medicine 364 (22), 2119-2127, 2011
10832011
Randomized study of high-dose and low-dose inter leukin-2 in patients with metastatic renal cancer
JC Yang, RM Sherry, SM Steinberg, SL Topalian, DJ Schwartzentruber, ...
Journal of clinical oncology: official journal of the American Society of …, 2003
10052003
A cancer cell program promotes T cell exclusion and resistance to checkpoint blockade
L Jerby-Arnon, P Shah, MS Cuoco, C Rodman, MJ Su, JC Melms, ...
Cell 175 (4), 984-997. e24, 2018
9972018
BRAF inhibition is associated with enhanced melanoma antigen expression and a more favorable tumor microenvironment in patients with metastatic melanoma
DT Frederick, A Piris, AP Cogdill, ZA Cooper, C Lezcano, CR Ferrone, ...
Clinical cancer research 19 (5), 1225-1231, 2013
9872013
Indoleamine 2, 3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation
P Hwu, MX Du, R Lapointe, M Do, MW Taylor, HA Young
The Journal of Immunology 164 (7), 3596-3599, 2000
9472000
T helper 17 cells promote cytotoxic T cell activation in tumor immunity
N Martin-Orozco, P Muranski, Y Chung, XO Yang, T Yamazaki, S Lu, ...
Immunity 31 (5), 787-798, 2009
9422009
Analysis of immune signatures in longitudinal tumor samples yields insight into biomarkers of response and mechanisms of resistance to immune checkpoint blockade
PL Chen, W Roh, A Reuben, ZA Cooper, CN Spencer, PA Prieto, JP Miller, ...
Cancer discovery 6 (8), 827-837, 2016
9112016
Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma
JF Toso, VJ Gill, P Hwu, FM Marincola, NP Restifo, DJ Schwartzentruber, ...
Journal of clinical oncology: official journal of the American Society of …, 2002
8292002
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