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Barbara Bryant
Barbara Bryant
Constellation Pharmaceuticals
Подтвержден адрес электронной почты в домене constellationpharma.com
Название
Процитировано
Процитировано
Год
Targeting MYC dependence in cancer by inhibiting BET bromodomains
JA Mertz, AR Conery, BM Bryant, P Sandy, S Balasubramanian, DA Mele, ...
Proceedings of the National Academy of Sciences 108 (40), 16669-16674, 2011
12802011
Promiscuous mutations activate the noncanonical NF-κB pathway in multiple myeloma
JJ Keats, R Fonseca, M Chesi, R Schop, A Baker, WJ Chng, S Van Wier, ...
Cancer cell 12 (2), 131-144, 2007
12122007
Characterizing gene sets with FuncAssociate
GF Berriz, OD King, B Bryant, C Sander, FP Roth
Bioinformatics 19 (18), 2502-2504, 2003
5972003
Gene expression profiling and correlation with outcome in clinical trials of the proteasome inhibitor bortezomib
G Mulligan, C Mitsiades, B Bryant, F Zhan, WJ Chng, S Roels, E Koenig, ...
Hematology 63, 2005
4612005
Mapping of a gene for type 2 diabetes associated with an insulin secretion defect by a genome scan in Finnish families
MM Mahtani, E Widén, M Lehto, J Thomas, M McCarthy, J Brayer, ...
Nature genetics 14 (1), 90-94, 1996
4191996
Molecular dissection of hyperdiploid multiple myeloma by gene expression profiling
WJ Chng, S Kumar, S VanWier, G Ahmann, T Price-Troska, K Henderson, ...
Cancer research 67 (7), 2982-2989, 2007
3102007
ART 1 and pattern clustering
B Moore
Proceedings of the 1988 connectionist models summer school, 174-185, 1989
2991989
BET bromodomain inhibition suppresses TH17-mediated pathology
DA Mele, A Salmeron, S Ghosh, HR Huang, BM Bryant, JM Lora
Journal of experimental medicine 210 (11), 2181-2190, 2013
2542013
AACR-FDA-NCI Cancer Biomarkers Collaborative consensus report: advancing the use of biomarkers in cancer drug development
SN Khleif, JH Doroshow, WN Hait
Clinical Cancer Research 16 (13), 3299-3318, 2010
2302010
Identification of cervical cancer markers by cDNA and tissue microarrays
Y Chen, C Miller, R Mosher, X Zhao, J Deeds, M Morrissey, B Bryant, ...
Cancer research 63 (8), 1927, 2003
2142003
EZH2 inhibitor efficacy in non-Hodgkin’s lymphoma does not require suppression of H3K27 monomethylation
WD Bradley, S Arora, J Busby, S Balasubramanian, VS Gehling, ...
Chemistry & biology 21 (11), 1463-1475, 2014
1642014
A quantitative atlas of histone modification signatures from human cancer cells
G LeRoy, PA DiMaggio, EY Chan, BM Zee, MA Blanco, B Bryant, ...
Epigenetics & chromatin 6, 1-14, 2013
1512013
The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition
WJ Chng, E Braggio, G Mulligan, B Bryant, E Remstein, R Valdez, ...
Blood, The Journal of the American Society of Hematology 111 (3), 1603-1609, 2008
1452008
An alternative approach to ChIP-Seq normalization enables detection of genome-wide changes in histone H3 lysine 27 trimethylation upon EZH2 inhibition
B Egan, CC Yuan, ML Craske, P Labhart, GD Guler, D Arnott, TM Maile, ...
PloS one 11 (11), e0166438, 2016
1402016
Discovery, design, and optimization of isoxazole azepine BET inhibitors
VS Gehling, MC Hewitt, RG Vaswani, Y Leblanc, A Côté, CG Nasveschuk, ...
ACS medicinal chemistry letters 4 (9), 835-840, 2013
1242013
Methods for the identification, assessment, and treatment of patients with cancer therapy
BM Bryant, AI Damokosh, G Mulligan
US Patent 8,278,038, 2012
123*2012
Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
AR Conery, RC Centore, A Neiss, PJ Keller, S Joshi, KL Spillane, ...
Elife 5, e10483, 2016
1132016
Pharmacological inhibition of the histone lysine demethylase KDM1A suppresses the growth of multiple acute myeloid leukemia subtypes
JP McGrath, KE Williamson, S Balasubramanian, S Odate, S Arora, ...
Cancer research 76 (7), 1975-1988, 2016
1032016
High-risk myeloma: A gene expression–based risk-stratification model for newly diagnosed multiple myeloma treated with high-dose therapy is predictive of outcome in relapsed …
F Zhan, B Barlogie, G Mulligan, JD Shaughnessy Jr, B Bryant
Blood 111 (2), 968-969, 2008
832008
Assessment of chromosomal alterations to predict clinical outcome of bortezomib treatment
BM Bryant, H Danaee, GJ Mulligan
US Patent App. 12/454,944, 2010
772010
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