Synthesis and biological evaluation of substituted (thieno [2, 3-d] pyrimidin-4-ylthio) carboxylic acids as inhibitors of human protein kinase CK2 AG Golub, VG Bdzhola, NV Briukhovetska, AO Balanda, OP Kukharenko, ... European journal of medicinal chemistry 46 (3), 870-876, 2011 | 83 | 2011 |
Discovery and characterization of synthetic 4′-hydroxyflavones—New CK2 inhibitors from flavone family AG Golub, VG Bdzhola, OV Ostrynska, IV Kyshenia, VM Sapelkin, ... Bioorganic & medicinal chemistry 21 (21), 6681-6689, 2013 | 37 | 2013 |
Structure-based discovery of novel flavonol inhibitors of human protein kinase CK2 AG Golub, VG Bdzhola, YV Kyshenia, VM Sapelkin, AO Prykhod’ko, ... Molecular and cellular biochemistry 356, 107-115, 2011 | 35 | 2011 |
Design, synthesis and evaluation of 3-quinoline carboxylic acids as new inhibitors of protein kinase CK2 AR Syniugin, OV Ostrynska, MO Chekanov, GP Volynets, SA Starosyla, ... Journal of Enzyme Inhibition and Medicinal Chemistry 31 (sup4), 160-169, 2016 | 30 | 2016 |
Design and synthesis of novel protein kinase CK2 inhibitors on the base of 4-aminothieno [2, 3-d] pyrimidines OV Ostrynska, AO Balanda, VG Bdzhola, AG Golub, IM Kotey, ... European Journal of Medicinal Chemistry 115, 148-160, 2016 | 26 | 2016 |
Dihydrobenzo[4,5]imidazo[1,2-a]pyrimidine-4-ones as a new class of CK2 inhibitors MV Protopopov, OV Ostrynska, SA Starosyla, MA Vodolazhenko, ... Molecular Diversity 22, 991-998, 2018 | 7 | 2018 |
Design, synthesis and biological evaluation of 2-aminopyrimidinones and their 6-aza-analogs as a new class of CK2 inhibitors MO Chekanov, OV Ostrynska, SS Tarnavskyi, AR Synyugin, ... Journal of Enzyme Inhibition and Medicinal Chemistry 29 (5), 639-646, 2014 | 6 | 2014 |
Design, synthesis and evaluation of 2-phenylisothiazolidin-3-one-1, 1-dioxides as a new class of human protein kinase CK2 inhibitors MO Chekanov, OV Ostrynska, AR Synyugin, VG Bdzhola, SM Yarmoluk Journal of Enzyme Inhibition and Medicinal Chemistry 29 (3), 338-343, 2014 | 5 | 2014 |
Search of protein kinase CK2 inhibitors based on purine-2, 6-diones derivatives MV Protopopov, OV Ostrynska, DH Ivanchenko, SA Starosyla, ... The Ukrainian Biochemical Journal, 32-39, 2017 | 4 | 2017 |
The synthesis of 5-hetarylamino-3-aryl-1H-indazoles as inhibitors of protein kinase CK2 MV Protopopov, VS Vdovin, SS Lukashov, OV Ostrynska, IP Borysenko, ... Biopolymers & Cell 36 (6), 466, 2020 | 3 | 2020 |
Evaluation of in vitro activity and SAR study of the novel hetarylamino-3-aryl-1H-indazole derivatives as inhibitors of protein kinase CK2 MV Protopopov, VS Vdovin, SS Lukashov, OV Ostrynska, IP Borysenko, ... Biopolymers and Cell 37 (1), 62-72, 2021 | 1 | 2021 |
Âèçíà÷åííÿ àêòèâíîñò³ in vitro òà àíàë³ç ñï³ââ³äíîøåííÿ ñòðóêòóðà-àêòèâí³ñòü íîâèõ ãåòåðîöèêë³÷íèõ ïîõ³äíèõ 5-àì³íî-3-àðèë-1H-³íäàçîëó ÿê ³íã³á³òîð³â ïðîòå¿íê³íàçè CK2 Ì Ïðîòîïîïîâ, ÂÑ Âäîâ³í, ÑÑ Ëóêàøîâ, ΠÎñòðèíñüêà, ... Biopolymers and Cell 37 (1), 62-72, 2021 | | 2021 |
Ñèíòåç 5-ãåòàðèëàì³íî-3-àðèë-1H-³íäàçîë³â ÿê ³íã³á³òîð³â ïðîòå¿íê³íàçè CK2 Ì Ïðîòîïîïîâ, ÂÑ Âäîâ³í, ÑÑ Ëóêàøîâ, ΠÎñòðèíñüêà, ... Biopolymers and Cell 36 (6), 466-476, 2020 | | 2020 |
Õ³ì³÷íà îïòèì³çàö³ÿ àì³ä³â 3 êàðáîêñèõ³íîë³íó ÿê ³íã³á³òîð³â ïðîòå¿íê³íàçè ÑÊ2 ΠÎñòðèíñüêà, ÀÐ Ñèíþã³í, ÌÎ ×åêàíîâ, Ì Ïðîòîïîïîâ, ... Ukrainica Bioorganica Acta 1, 38-45, 2016 | | 2016 |
Search of new inhibitors of protein kinase CK2 among 2-pyridone derivatives. OV Ostrynska, IV Ukrainets, LV Sidorenko, YA Starosyla, MV Protopopov, ... Ukrainica Bioorganica Acta 13 (2), 2015 | | 2015 |
Cytotoxicity of 1-benzyl-3-chloro-4-anilino-2, 5-dihydropyrrole-2, 5-dione derivatives. SS Tarnavskyi, OV Ostrynska, GP Volynets, KV Kotsarenko, YA Starosyla, ... Ukrainica Bioorganica Acta 13 (2), 2015 | | 2015 |
EFFECT OF INHIBITORS OF PROTEIN KINASE CK2 ON THE ACTIVITY ITS CATALYTIC SUBUNITS CÊ2α AND CÊ2α OV Ostrynska, OP Kukharenko, VG Bdzhola, SM Yarmoluk Biotechnologia 7 (6), 2014 | | 2014 |
Ñèíòåç 1 àëê³ë, 1 àðèë 2 áåíç³ì³äàçîëîí³â òà àì³ä³â 2 îêñîáåíç³ì³äàçîë 5 êàðáîíîâî¿ êèñëîòè ÂÌ Íàóì÷óê, ÑÑ Ëóêàøîâ, ΠÎñòðèíñüêà, ²Ï Áîðèñåíêî, ²Ì Ôåñóí, ... Ukrainica Bioorganica Acta 2, 40-46, 2014 | | 2014 |
Effect of inhibitors of protein kinase CK2 on the activity its catalytic subunits ñê2α and ñê2α OV Ostrynska, OP Kukharenko, VG Bdzhola, SM Yarmoluk Biotechnologia Acta 7 (6), 29-39, 2014 | | 2014 |
Ïîøóê íîâèõ íèçüêîìîëåêóëÿðíèõ ³íã³á³òîð³â ïðîòå¿íê³íàçè ÑÊ2 ñåðåä ïîõ³äíèõ 3, 4, 5, 6 òåòðàã³äðîò³îï³ðàíî [2, 3 d] ò³àçîëó ΠÎñòðèíñüêà, Âà Áäæîëà, ÎÏ Êóõàðåíêî, ÑÌ ßðìîëþê Ukrainica Bioorganica Acta 2, 25-29, 2012 | | 2012 |