| Phosphatidylinositol-3-OH kinase direct target of Ras P Rodriguez-Viciana, PH Warne, R Dhand, B Vanhaesebroeck, I Gout, ... Nature 370 (6490), 527-532, 1994 | 2670 | 1994 |
| The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins LS Harrington, GM Findlay, A Gray, T Tolkacheva, S Wigfield, H Rebholz, ... The Journal of cell biology 166 (2), 213-223, 2004 | 1381 | 2004 |
| A survey of the humoral immune response of cancer patients to a panel of human tumor antigens E Stockert, E Jäger, YT Chen, MJ Scanlan, I Gout, J Karbach, M Arand, ... The Journal of experimental medicine 187 (8), 1349-1354, 1998 | 909 | 1998 |
| Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit ID Hiles, M Otsu, S Volinia, MJ Fry, I Gout, R Dhand, G Panayotou, ... Cell 70 (3), 419-429, 1992 | 907 | 1992 |
| Characterization of two 85 kd proteins that associate with receptor tyrosine kinases, middle-T/pp60c-src complexes, and PI3-kinase M Otsu, I Hiles, I Gout, MJ Fry, F Ruiz-Larrea, G Panayotou, A Thompson, ... Cell 65 (1), 91-104, 1991 | 907 | 1991 |
| Phospholipase D: a downstream effector of ARF in granulocytes S Cockcroft, GMH Thomas, A Fensome, B Geny, E Cunningham, I Gout, ... Science 263 (5146), 523-526, 1994 | 800 | 1994 |
| Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase. K Salim, MJ Bottomley, E Querfurth, MJ Zvelebil, I Gout, R Scaife, ... The EMBO journal 15 (22), 6241-6250, 1996 | 730 | 1996 |
| The GTPase dynamin binds to and is activated by a subset of SH3 domains I Gout, R Dhand, ID Hiles, MJ Fry, G Panayotou, P Das, O Truong, ... Cell 75 (1), 25-36, 1993 | 693 | 1993 |
| PI 3‐kinase is a dual specificity enzyme: autoregulation by an intrinsic protein‐serine kinase activity. R Dhand, I Hiles, G Panayotou, S Roche, MJ Fry, I Gout, NF Totty, ... The EMBO journal 13 (3), 522-533, 1994 | 607 | 1994 |
| Phosphatidylinositol-3, 4, 5-trisphosphate (PtdIns-3, 4, 5-P3)/Tec kinase-dependent calcium signaling pathway: a target for SHIP-mediated inhibitory signals AM Scharenberg, O El-Hillal, DA Fruman, LO Beitz, Z Li, S Lin, I Gout, ... The EMBO journal 17 (7), 1961-1972, 1998 | 549 | 1998 |
| PI 3‐kinase: structural and functional analysis of intersubunit interactions. R Dhand, K Hara, I Hiles, B Bax, I Gout, G Panayotou, MJ Fry, ... The EMBO journal 13 (3), 511-521, 1994 | 433 | 1994 |
| Functions and regulation of the 70 kDa ribosomal S6 kinases TR Fenton, IT Gout The international journal of biochemistry & cell biology 43 (1), 47-59, 2011 | 395 | 2011 |
| Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression MJ Scanlan, I Gout, CM Gordon, B Williamson, E Stockert, AO Gure, ... Cancer Immunity 1 (1), 2001 | 278 | 2001 |
| Solution structure and ligand-binding site of the SH3 domain of the p85α subunit of phosphatidylinositol 3-kinase GW Booker, I Gout, A Kristina, PC Driscoll, J Boyd, MD Waterfield, ... Cell 73 (4), 813-822, 1993 | 234 | 1993 |
| FGF‐2 protects small cell lung cancer cells from apoptosis through a complex involving PKCε, B‐Raf and S6K2 OE Pardo, C Wellbrock, UK Khanzada, M Aubert, I Arozarena, S Davidson, ... The EMBO journal 25 (13), 3078-3088, 2006 | 229 | 2006 |
| Structure of an SH2 domain of the p85α subunit of phosphatidylinositol-3-OH kinase GW Booker, AL Breeze, AK Downing, G Panayotou, I Gout, MD Waterfield, ... Nature 358 (6388), 684-687, 1992 | 214 | 1992 |
| Human phosphoinositide 3-kinase C2β, the role of calcium and the C2 domain in enzyme activity A Arcaro, S Volinia, MJ Zvelebil, R Stein, SJ Watton, MJ Layton, I Gout, ... Journal of Biological Chemistry 273 (49), 33082-33090, 1998 | 205 | 1998 |
| Exome sequence reveals mutations in CoA synthase as a cause of neurodegeneration with brain iron accumulation S Dusi, L Valletta, TB Haack, Y Tsuchiya, P Venco, S Pasqualato, ... The American Journal of Human Genetics 94 (1), 11-22, 2014 | 200 | 2014 |
| Interactions between SH2 domains and tyrosine-phosphorylated platelet-derived growth factor β-receptor sequences: analysis of kinetic parameters by a novel biosensor-based approach G Panayotou, G Gish, P End, O Truong, I Gout, R Dhand, MJ Fry, I Hiles, ... Molecular and Cellular Biology 13 (6), 3567-3576, 1993 | 194 | 1993 |
| An SH3 domain and proline-rich sequence mediate an interaction between two components of the phagocyte NADPH oxidase complex. P Finan, Y Shimizu, I Gout, J Hsuan, O Truong, C Butcher, P Bennett, ... Journal of Biological Chemistry 269 (19), 13752-13755, 1994 | 191 | 1994 |
