Alejandro Schaffer
Alejandro Schaffer
Computer Scientist, National Institutes of Health
Verified email at helix.nih.gov - Homepage
TitleCited byYear
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
SF Altschul, TL Madden, AA Schäffer, J Zhang, Z Zhang, W Miller, ...
Nucleic acids research 25 (17), 3389-3402, 1997
724061997
Faster sequential genetic linkage computations.
RW Cottingham Jr, RM Idury, AA Schäffer
American journal of human genetics 53 (1), 252, 1993
15091993
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
AA Schäffer, L Aravind, TL Madden, S Shavirin, JL Spouge, YI Wolf, ...
Nucleic acids research 29 (14), 2994-3005, 2001
13682001
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
EO Glocker, D Kotlarz, K Boztug, EM Gertz, AA Schäffer, F Noyan, M Perro, ...
New England Journal of Medicine 361 (21), 2033-2045, 2009
11402009
STAT3 mutations in the hyper-IgE syndrome
SM Holland, FR DeLeo, HZ Elloumi, AP Hsu, G Uzel, N Brodsky, ...
New England Journal of Medicine 357 (16), 1608-1619, 2007
10232007
Mapping of a gene for Parkinson's disease to chromosome 4q21-q23
MH Polymeropoulos, JJ Higgins, LI Golbe, WG Johnson, SE Ide, ...
Science 274 (5290), 1197-1199, 1996
8881996
Protein database searches using compositionally adjusted substitution matrices
SF Altschul, JC Wootton, EM Gertz, R Agarwala, A Morgulis, AA Schäffer, ...
The FEBS journal 272 (20), 5101-5109, 2005
8572005
Avoiding recomputation in linkage analysis
AA Schaeffer, SK Gupta, K Shriram, RW Cottingham Jr
Human heredity 44 (4), 225-237, 1994
7341994
Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency
B Grimbacher, A Hutloff, M Schlesier, E Glocker, K Warnatz, R Dräger, ...
Nature immunology 4 (3), 261-268, 2003
7192003
Database indexing for production MegaBLAST searches
A Morgulis, G Coulouris, Y Raytselis, TL Madden, R Agarwala, ...
Bioinformatics 24 (16), 1757-1764, 2008
6922008
A homozygous CARD9 mutation in a family with susceptibility to fungal infections
EO Glocker, A Hennigs, M Nabavi, AA Schäffer, C Woellner, U Salzer, ...
New England Journal of Medicine 361 (18), 1727-1735, 2009
6452009
Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans
U Salzer, HM Chapel, ADB Webster, Q Pan-Hammarström, ...
Nature genetics 37 (8), 820-828, 2005
6212005
Graph spanners
D Peleg, AA Schäffer
Journal of graph theory 13 (1), 99-116, 1989
5861989
Domain enhanced lookup time accelerated BLAST
GM Boratyn, AA Schäffer, R Agarwala, SF Altschul, DJ Lipman, ...
Biology direct 7 (1), 12, 2012
4782012
A genetic linkage map of microsatellites in the domestic cat (Felis catus)
M Menotti-Raymond, VA David, LA Lyons, AA Schäffer, JF Tomlin, ...
Genomics 57 (1), 9-23, 1999
4621999
Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer
T Kuukasjärvi, R Karhu, M Tanner, M Kähkönen, A Schäffer, N Nupponen, ...
Cancer research 57 (8), 1597-1604, 1997
4511997
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations
D Schubert, C Bode, R Kenefeck, TZ Hou, JB Wing, A Kennedy, ...
Nature medicine 20 (12), 1410, 2014
4452014
Localization of a gene for an autosomal recessive form of juvenile Parkinsonism to chromosome 6q25. 2-27.
H Matsumine, M Saito, S Shimoda-Matsubayashi, H Tanaka, A Ishikawa, ...
American journal of human genetics 60 (3), 588, 1997
4431997
HAX1 deficiency causes autosomal recessive severe congenital neutropenia (Kostmann disease)
C Klein, M Grudzien, G Appaswamy, M Germeshausen, I Sandrock, ...
Nature genetics 39 (1), 86-92, 2007
4412007
Genetic linkage of hyper-IgE syndrome to chromosome 4
B Grimbacher, AA Schäffer, SM Holland, J Davis, JI Gallin, HL Malech, ...
The American Journal of Human Genetics 65 (3), 735-744, 1999
3681999
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Articles 1–20